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作者：Binietoglou, Ioannis; Allan, Oscar
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作者：Masood, Ehsan
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作者：Rath, Monalisha; Bergmann, Dominique
作者单位：Stanford University; Howard Hughes Medical Institute
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作者：Koh, Bong Ihn; Mohanakrishnan, Vishal; Jeong, Hyun-Woo; Park, Hongryeol; Kruse, Kai; Choi, Young Jun; Nieminen-Kelhae, Melina; Kumar, Rahul; Pereira, Raquel S.; Adams, Susanne; Lee, Hyuek Jong; Bixel, M. Gabriele; Vajkoczy, Peter; Krause, Daniela S.; Adams, Ralf H.
作者单位：Max Planck Society; Max Planck Society; Max Planck Society; University of Ulsan; Asan Medical Center; University of Ulsan; Asan Medical Center; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Free University of Berlin; Humboldt University of Berlin; Johannes Gutenberg University of Mainz; Goethe University Frankfurt; Institute for Basic Science - Korea (IBS)
摘要：The bone marrow microenvironment is a critical regulator of haematopoietic stem cell self-renewal and fate1. Although it is appreciated that ageing, chronic inflammation and other insults compromise bone marrow function and thereby negatively affect haematopoiesis2, it is not known whether different bone compartments exhibit distinct microenvironmental properties and functional resilience. Here we use imaging, pharmacological approaches and mouse genetics to uncover specialized properties of b...
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作者：Kosse, Christin; Ivanov, Jessica; Knight, Zachary; Pellegrino, Kyle; Friedman, Jeffrey
作者单位：Rockefeller University; Howard Hughes Medical Institute; University of California System; University of California San Francisco
摘要：The brain processes an array of stimuli, enabling the selection of appropriate behavioural responses, but the neural pathways linking interoceptive inputs to outputs for feeding are poorly understood1-3. Here we delineate a subcortical circuit in which brain-derived neurotrophic factor (BDNF)-expressing neurons in the ventromedial hypothalamus (VMH) directly connect interoceptive inputs to motor centres, controlling food consumption and jaw movements. VMHBDNF neuron inhibition increases food i...
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作者：Naddaf, Miryam
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作者：[Anonymous]
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作者：Linderholm, Anna
作者单位：Stockholm University; Swedish Museum of Natural History
摘要：Analyses of ancient DNA from aurochs - large, wild cattle that co-existed with humans for millennia - reveals how early humans tamed these beasts and bred them with domesticated cattle for strength and resilience.
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作者：Williams, Brooke A.; Beyer, Hawthorne L.; Fagan, Matthew E.; Chazdon, Robin L.; Schmoeller, Marina; Sprenkle-Hyppolite, Starry; Griscom, Bronson W.; Watson, James E. M.; Tedesco, Anazelia M.; Gonzalez-Roglich, Mariano; Daldegan, Gabriel A.; Bodin, Blaise; Celentano, Danielle; Wilson, Sarah Jane; Rhodes, Jonathan R.; Alexandre, Nikola S.; Kim, Do-Hyung; Bastos, Diego; Crouzeilles, Renato
作者单位：Queensland University of Technology (QUT); University of Queensland; University of Queensland; University System of Maryland; University of Maryland Baltimore County; University of the Sunshine Coast; Conservation International; Conservation International; University of Victoria; UNICEF
摘要：Extensive forest restoration is a key strategy to meet nature-based sustainable development goals and provide multiple social and environmental benefits1. Yet achieving forest restoration at scale requires cost-effective methods2. Tree planting in degraded landscapes is a popular but costly forest restoration method that often results in less biodiverse forests when compared to natural regeneration techniques under similar conditions3. Here we assess the current spatial distribution of pantrop...
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作者：Allan, James
作者单位：UK Research & Innovation (UKRI); Natural Environment Research Council (NERC); NERC National Centre for Atmospheric Science; University of Manchester
