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作者:Pearson, Helen
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作者:Castelvecchi, Davide
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作者:Arezki, Rabah; Landau, Jean-Pierre; van der Ploeg, Rick
作者单位:Centre National de la Recherche Scientifique (CNRS); Harvard University; University of Oxford; University of Amsterdam; Centre for Economic Policy Research - UK
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作者:Little, Hannah
作者单位:University of Liverpool
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作者:Yang, Hong
作者单位:University of Reading
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作者:Mallapaty, Smriti
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作者:Curtius, Joachim; Heinritzi, Martin; Beck, Lisa J.; Poehlker, Mira L.; Tripathi, Nidhi; Krumm, Bianca E.; Holzbeck, Philip; Nussbaumer, Clara M.; Pardo, Lianet Hernandez; Klimach, Thomas; Barmpounis, Konstantinos; Andersen, Simone T.; Bardakov, Roman; Bohn, Birger; Cecchini, Micael A.; Chaboureau, Jean-Pierre; Dauhut, Thibaut; Dienhart, Dirk; Doerich, Raphael; Edtbauer, Achim; Giez, Andreas; Hartmann, Antonia; Holanda, Bruna A.; Joppe, Philipp; Kaiser, Katharina; Keber, Timo; Klebach, Hannah; Krueger, Ovid O.; Kuerten, Andreas; Mallaun, Christian; Marno, Daniel; Martinez, Monica; Monteiro, Carolina; Nelson, Carolina; Ort, Linda; Raj, Subha S.; Richter, Sarah; Ringsdorf, Akima; Rocha, Fabio; Simon, Mario; Sreekumar, Sreedev; Tsokankunku, Anywhere; Unfer, Gabriela R.; Valenti, Isabella D.; Wang, Nijing; Zahn, Andreas; Zauner-Wieczorek, Marcel; Albrecht, Rachel I.; Andreae, Meinrat O.; Artaxo, Paulo; Crowley, John N.; Fischer, Horst; Harder, Hartwig; Herdies, Dirceu L.; Machado, Luiz A. T.; Poehlker, Christopher; Poeschl, Ulrich; Possner, Anna; Pozzer, Andrea; Schneider, Johannes; Williams, Jonathan; Lelieveld, Jos
作者单位:Goethe University Frankfurt; Leibniz Association; Leibniz Institut fur Tropospharenforschung (TROPOS); Leipzig University; Max Planck Society; Stockholm University; Stockholm University; Helmholtz Association; Research Center Julich; Universidade de Sao Paulo; Institut de Recherche pour le Developpement (IRD); Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Centre National de la Recherche Scientifique (CNRS); LAERO; Helmholtz Association; German Aerospace Centre (DLR); Johannes Gutenberg University of Mainz; Instituto Nacional de Pesquisas Espaciais (INPE); Institute Nacional de Pesquisas da Amazonia; Helmholtz Association; Karlsruhe Institute of Technology; King Saud University; University of California System; University of California San Diego; Scripps Institution of Oceanography; Universidade de Sao Paulo; Universidade de Sao Paulo
摘要:New particle formation (NPF) in the tropical upper troposphere is a globally important source of atmospheric aerosols1, 2, 3-4. It is known to occur over the Amazon basin, but the nucleation mechanism and chemical precursors have yet to be identified2. Here we present comprehensive in situ aircraft measurements showing that extremely low-volatile oxidation products of isoprene, particularly certain organonitrates, drive NPF in the Amazonian upper troposphere. The organonitrates originate from ...
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作者:Roediger, Sven; Le Saux, Emilien; Boehm, Philip; Morandi, Bill
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich
摘要:Cross-electrophile coupling reactions have evolved into a major strategy for rapidly assembling important organic molecules1. Two readily accessible electrophiles are coupled to form new C-C bonds, providing a key advantage over traditional cross-coupling strategies that require the preformation of reactive organometallic species. Yet, the formation of C(sp3)-C(sp3) bonds that form the core of nearly all organic compounds remains highly challenging with current approaches, calling for the desi...
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作者:Vazquez, Almudena Carrera; Tornow, Caroline; Riste, Diego; Woerner, Stefan; Takita, Maika; Egger, Daniel J.
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich
摘要:Quantum computers process information with the laws of quantum mechanics. Current quantum hardware is noisy, can only store information for a short time and is limited to a few quantum bits, that is, qubits, typically arranged in a planar connectivity1. However, many applications of quantum computing require more connectivity than the planar lattice offered by the hardware on more qubits than is available on a single quantum processing unit (QPU). The community hopes to tackle these limitation...
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作者:Calabria, Andrea; Spinozzi, Giulio; Cesana, Daniela; Buscaroli, Elena; Benedicenti, Fabrizio; Pais, Giulia; Gazzo, Francesco; Scala, Serena; Lidonnici, Maria Rosa; Scaramuzza, Samantha; Albertini, Alessandra; Esposito, Simona; Tucci, Francesca; Canarutto, Daniele; Omrani, Maryam; De Mattia, Fabiola; Dionisio, Francesca; Giannelli, Stefania; Marktel, Sarah; Fumagalli, Francesca; Calbi, Valeria; Cenciarelli, Sabina; Ferrua, Francesca; Gentner, Bernhard; Caravagna, Giulio; Ciceri, Fabio; Naldini, Luigi; Ferrari, Giuliana; Aiuti, Alessandro; Montini, Eugenio
作者单位:Vita-Salute San Raffaele University; IRCCS Ospedale San Raffaele; Fondazione Telethon; San Raffaele Telethon Institute For Gene Therapy (Sr-Tiget); University of Trieste; Polytechnic University of Milan; Vita-Salute San Raffaele University; IRCCS Ospedale San Raffaele; Vita-Salute San Raffaele University
摘要:Haematopoietic stem cell (HSC) gene therapy (GT) may provide lifelong reconstitution of the haematopoietic system with gene-corrected cells1. However, the effects of underlying genetic diseases, replication stress and ageing on haematopoietic reconstitution and lineage specification remain unclear. In this study, we analysed haematopoietic reconstitution in 53 patients treated with lentiviral-HSC-GT for diverse conditions such as metachromatic leukodystrophy2,3 (MLD), Wiskott-Aldrich syndrome4...