2024

最新文章

• China seeks global impact and recognition AI翻译
  作者：Baker, Simon
• Lack of cannabis research boosts misinformation AI翻译
  作者：Torkamaneh, Davoud
  作者单位：Laval University
• Exclusive: How NASA astronauts are training to walk on the Moon in 2026 AI翻译
  作者：Witze, Alexandra
  摘要：Simulated lunar exploration in an Arizona volcanic field this month helped astronauts to prepare for doing geology in harsh conditions at the lunar south pole. Nature joined mission control.
• Chinese science still has room to grow AI翻译
  作者：Wu, Bo; Baker, Simon; Crew, Bec; Maxwell, Tanner
• Negotiating a pandemic treaty is just the first step - how will countries comply? AI翻译
  作者：Park, Tae Jung
  作者单位：Korea Advanced Institute of Science & Technology (KAIST)
  摘要：Governments must act now on vaccine and pathogen-sample sharing, or any agreement will be a promise only on paper.
• Capturing electron-driven chiral dynamics in UV-excited molecules AI翻译
  作者：Wanie, Vincent; Bloch, Etienne; Mansson, Erik P.; Colaizzi, Lorenzo; Ryabchuk, Sergey; Saraswathula, Krishna; Ordonez, Andres F.; Ayuso, David; Smirnova, Olga; Trabattoni, Andrea; Blanchet, Valerie; Ben Amor, Nadia; Heitz, Marie-Catherine; Mairesse, Yann; Pons, Bernard; Calegari, Francesca
  作者单位：Helmholtz Association; Deutsches Elektronen-Synchrotron (DESY); Universite de Bordeaux; CEA; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Physics (INP); University of Hamburg; University of Hamburg; Imperial College London; Leibniz Association; Max Born Institute for Nonlinear Optics & Short Term Spectroscopy; Technical University of Berlin; Leibniz University Hannover; Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Centre National de la Recherche Scientifique (CNRS); Polytechnic University of Milan; University of London; Queen Mary University London
  摘要：Chiral molecules, used in applications such as enantioselective photocatalysis(1), circularly polarized light detection(2) and emission(3) and molecular switches(4,5), exist in two geometrical configurations that are non-superimposable mirror images of each other. These so-called (R) and (S) enantiomers exhibit different physical and chemical properties when interacting with other chiral entities. Attosecond technology might enable influence over such interactions, given that it can probe and ...
• An alternative cell cycle coordinates multiciliated cell differentiation AI翻译
  作者：Choksi, Semil P.; Byrnes, Lauren E.; Konjikusic, Mia J.; Tsai, Benedict W. H.; Deleon, Rachel; Lu, Quanlong; Westlake, Christopher J.; Reiter, Jeremy F.
  作者单位：University of California System; University of California San Francisco; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); Chan Zuckerberg Initiative (CZI)
  摘要：The canonical mitotic cell cycle coordinates DNA replication, centriole duplication and cytokinesis to generate two cells from one(1). Some cells, such as mammalian trophoblast giant cells, use cell cycle variants like the endocycle to bypass mitosis(2). Differentiating multiciliated cells, found in the mammalian airway, brain ventricles and reproductive tract, are post-mitotic but generate hundreds of centrioles, each of which matures into a basal body and nucleates a motile cilium(3,4). Seve...
• A whole-slide foundation model for digital pathology from real-world data AI翻译
  作者：Xu, Hanwen; Usuyama, Naoto; Bagga, Jaspreet; Zhang, Sheng; Rao, Rajesh; Naumann, Tristan; Wong, Cliff; Gero, Zelalem; Gonzalez, Javier; Gu, Yu; Xu, Yanbo; Wei, Mu; Wang, Wenhui; Ma, Shuming; Wei, Furu; Yang, Jianwei; Li, Chunyuan; Gao, Jianfeng; Rosemon, Jaylen; Bower, Tucker; Lee, Soohee; Weerasinghe, Roshanthi; Wright, Bill J.; Robicsek, Ari; Piening, Brian; Bifulco, Carlo; Wang, Sheng; Poon, Hoifung
  作者单位：Microsoft; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
  摘要：Digital pathology poses unique computational challenges, as a standard gigapixel slide may comprise tens of thousands of image tiles(1-3). Prior models have often resorted to subsampling a small portion of tiles for each slide, thus missing the important slide-level context(4). Here we present Prov-GigaPath, a whole-slide pathology foundation model pretrained on 1.3 billion 256x256 pathology image tiles in 171,189 whole slides from Providence, a large US health network comprising 28 cancer cen...
• BIZARRE BACTERIA DEFY TEXTBOOKS BY WRITING NEW GENES AI翻译
  作者：Callaway, Ewen
  摘要：Bacterial defensive systems scramble the standard workflow of life.
• Life-cycle-coupled evolution of mitosis in close relatives of animals AI翻译
  作者：Shah, Hiral; Olivetta, Marine; Bhickta, Chandni; Ronchi, Paolo; Trupinic, Monika; Tromer, Eelco C.; Tolic, Iva M.; Schwab, Yannick; Dudin, Omaya; Dey, Gautam
  作者单位：European Molecular Biology Laboratory (EMBL); Swiss Institute Experimental Cancer Research; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss School of Public Health (SSPH+); European Molecular Biology Laboratory (EMBL); University of Groningen
  摘要：Eukaryotes have evolved towards one of two extremes along a spectrum of strategies for remodelling the nuclear envelope during cell division: disassembling the nuclear envelope in an open mitosis or constructing an intranuclear spindle in a closed mitosis 1,2 . Both classes of mitotic remodelling involve key differences in the core division machinery but the evolutionary reasons for adopting a specific mechanism are unclear. Here we use an integrated comparative genomics and ultrastructural im...