2024

最新文章

• A two-site Kitaev chain in a two-dimensional electron gas AI翻译
  作者：ten Haaf, Sebastiaan L. D.; Wang, Qingzhen; Bozkurt, A. Mert; Liu, Chun-Xiao; Kulesh, Ivan; Kim, Philip; Xiao, Di; Thomas, Candice; Manfra, Michael J.; Dvir, Tom; Wimmer, Michael; Goswami, Srijit
  作者单位：Delft University of Technology; Delft University of Technology; Purdue University System; Purdue University; Purdue University System; Purdue University; Purdue University in Indianapolis; Purdue University System; Purdue University
  摘要：Artificial Kitaev chains can be used to engineer Majorana bound states (MBSs) in superconductor-semiconductor hybrids1-4. In this work, we realize a two-site Kitaev chain in a two-dimensional electron gas by coupling two quantum dots through a region proximitized by a superconductor. We demonstrate systematic control over inter-dot couplings through in-plane rotations of the magnetic field and via electrostatic gating of the proximitized region. This allows us to tune the system to sweet spots...
• Nuclear position and local acetyl-CoA production regulate chromatin state AI翻译
  作者：Willnow, Philipp; Teleman, Aurelio A.
  作者单位：Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg
  摘要：Histone acetylation regulates gene expression, cell function and cell fate(1). Here we study the pattern of histone acetylation in the epithelial tissue of the Drosophila wing disc. H3K18ac, H4K8ac and total lysine acetylation are increased in the outer rim of the disc. This acetylation pattern is controlled by nuclear position, whereby nuclei continuously move from apical to basal locations within the epithelium and exhibit high levels of H3K18ac when they are in proximity to the tissue surfa...
• IMPROVE TRAVEL GRANTS AI翻译
  作者：Carter, Laura; Wolz, Laura; Pallett, Laura J.
  作者单位：University of Leeds; University of Manchester; University of London; University College London
  摘要：Three scientist mothers call for a change in how conference childcare costs are reimbursed, drawing on their personal experiences.
• Scaling neural machine translation to 200 languages AI翻译
  作者：Costa-Jussa, Marta R.; Cross, James; Celebi, Onur; Elbayad, Maha; Heafield, Kenneth; Heffernan, Kevin; Kalbassi, Elahe; Lam, Janice; Licht, Daniel; Maillard, Jean; Sun, Anna; Wang, Skyler; Wenzek, Guillaume; Youngblood, Al; Akula, Bapi; Barrault, Loic; Gonzalez, Gabriel Mejia; Hansanti, Prangthip; Hoffman, John; Jarrett, Semarley; Sadagopan, Kaushik Ram; Rowe, Dirk; Spruit, Shannon; Tran, Chau; Andrews, Pierre; Ayan, Necip Fazil; Bhosale, Shruti; Edunov, Sergey; Fan, Angela; Gao, Cynthia; Goswami, Vedanuj; Guzman, Francisco; Koehn, Philipp; Mourachko, Alexandre; Ropers, Christophe; Saleem, Safiyyah; Schwenk, Holger; Wang, Jeff
  作者单位：University of California System; University of California Berkeley; Johns Hopkins University
  摘要：The development of neural techniques has opened up new avenues for research in machine translation. Today, neural machine translation (NMT) systems can leverage highly multilingual capacities and even perform zero-shot translation, delivering promising results in terms of language coverage and quality. However, scaling quality NMT requires large volumes of parallel bilingual data, which are not equally available for the 7,000+ languages in the world 1 . Focusing on improving the translation qu...
• Hybrid working has benefits over fully in-person working - the evidence mounts AI翻译
  作者：[Anonymous]
  摘要：Some employers are backing away from hybrid working, but research suggests that they need not be concerned. A woman works on the laptop at her desk in her home. A monitor and two plants are also seen on the desk
• The sex of organ geometry AI翻译
  作者：Blackie, Laura; Gaspar, Pedro; Mosleh, Salem; Lushchak, Oleh; Kong, Lingjin; Jin, Yuhong; Zielinska, Agata P.; Cao, Boxuan; Mineo, Alessandro; Silva, Bryon; Ameku, Tomotsune; Lim, Shu En; Mao, Yanlan; Prieto-Godino, Lucia; Schoborg, Todd; Varela, Marta; Mahadevan, L.; Miguel-Aliaga, Irene
  作者单位：Imperial College London; Francis Crick Institute; Harvard University; MRC Laboratory Molecular Biology; University of London; University College London; University of London; University College London; University of Wyoming; Imperial College London; Harvard University; University System of Maryland; University of Maryland Eastern Shore
  摘要：Organs have a distinctive yet often overlooked spatial arrangement in the body(1-5). We propose that there is a logic to the shape of an organ and its proximity to its neighbours. Here, by using volumetric scans of many Drosophila melanogaster flies, we develop methods to quantify three-dimensional features of organ shape, position and interindividual variability. We find that both the shapes of organs and their relative arrangement are consistent yet differ between the sexes, and identify une...
• Identification of SARS-CoV-2 inhibitors using lung and colonic organoids (vol 589, pg 270, 2021) AI翻译
  作者：Han, Yuling; Duan, Xiaohua; Yang, Liuliu; Nilsson-Payant, Benjamin E.; Wang, Pengfei; Duan, Fuyu; Tang, Xuming; Yaron, Tomer M.; Zhang, Tuo; Uhl, Skyler; Bram, Yaron; Richardson, Chanel; Zhu, Jiajun; Zhao, Zeping; Redmond, David; Houghton, Sean; Nguyen, Duc-Huy T.; Xu, Dong; Wang, Xing; Jessurun, Jose; Borczuk, Alain; Huang, Yaoxing; Johnson, Jared L.; Liu, Yuru; Xiang, Jenny; Wang, Hui; Cantley, Lewis C.; tenOever, Benjamin R.; Ho, David D.; Pan, Fong Cheng; Evans, Todd; Chen, Huanhuan Joyce; Schwartz, Robert E.; Chen, Shuibing
  作者单位：Cornell University; Weill Cornell Medicine; Shanghai Jiao Tong University; Icahn School of Medicine at Mount Sinai; Columbia University; University of Chicago; University of Chicago; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; Cornell University; Weill Cornell Medicine
• A molecular map of the immune response region from the major histocompatibility complex of the mouse (vol 300, pg 35, 1982) AI翻译
  作者：Steinmetz, Michael; Minard, Karyl; Horvath, Suzanna; McNicholast, Janet; Frelinger, Jeffrey; Wake, Claire; Long, Eric; Mach, Bernard; Hood, Leroy
  作者单位：California Institute of Technology; Stanford University; University of Southern California; University of Geneva
• Monolithic three-dimensional tier-by-tier integration via van der Waals lamination AI翻译
  作者：Lu, Donglin; Chen, Yang; Lu, Zheyi; Ma, Likuan; Tao, Quanyang; Li, Zhiwei; Kong, Lingan; Liu, Liting; Yang, Xiaokun; Ding, Shuimei; Liu, Xiao; Li, Yunxin; Wu, Ruixia; Wang, Yiliu; Hu, Yuanyuan; Duan, Xidong; Liao, Lei; Liu, Yuan
  作者单位：Hunan University; Hunan University; Hunan University
  摘要：Two-dimensional (2D) semiconductors have shown great potential for monolithic three-dimensional (M3D) integration due to their dangling-bonds-free surface and the ability to integrate to various substrates without the conventional constraint of lattice matching(1-10). However, with atomically thin body thickness, 2D semiconductors are not compatible with various high-energy processes in microelectronics(11-13), where the M3D integration of multiple 2D circuit tiers is challenging. Here we repo...
• Brazil's plummeting graduate enrolments hint at declining interest in academic science careers AI翻译
  作者：Andrade, Rodrigo de Oliveira
  摘要：The total number of individuals entering master's and doctoral programmes dropped 12% between 2019 and 2022, reaching the lowest level in nearly a decade.