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作者:Lenharo, Mariana
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作者:Watanabe, Masahiro; Kang, Sarah M.; Collins, Matthew; Hwang, Yen-Ting; McGregor, Shayne; Stuecker, Malte F.
作者单位:University of Tokyo; Max Planck Society; University of Exeter; National Taiwan University; Monash University; University of Hawaii System; University of Hawaii Manoa; University of Hawaii System; University of Hawaii Manoa
摘要:Changes in the sea surface temperature (SST) pattern in the tropical Pacific modulate radiative feedbacks to greenhouse gas forcing, the pace of global warming and regional climate impacts. Therefore, elucidating the drivers of the pattern is critically important for reducing uncertainties in future projections. However, the causes of observed changes over recent decades, an enhancement of the zonal SST contrast coupled with a strengthening of the Walker circulation, are still debated. Here we...
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作者:[Anonymous]
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作者:Byrns, China N.; Perlegos, Alexandra E.; Miller, Karl N.; Jin, Zhecheng; Carranza, Faith R.; Manchandra, Palak; Beveridge, Connor H.; Randolph, Caitlin E.; Chaluvadi, V. Sai; Zhang, Shirley L.; Srinivasan, Ananth R.; Bennett, F. C.; Sehgal, Amita; Adams, Peter D.; Chopra, Gaurav; Bonini, Nancy M.
作者单位:University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; Sanford Burnham Prebys Medical Discovery Institute; Purdue University System; Purdue University; University of Pennsylvania; Howard Hughes Medical Institute; University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; Purdue University System; Purdue University; Purdue University System; Purdue University; Purdue University System; Purdue University; Purdue University System; Purdue University
摘要:Senescence is a cellular state linked to ageing and age-onset disease across many mammalian species(1,2). Acutely, senescent cells promote wound healing(3,4) and prevent tumour formation5; but they are also pro-inflammatory, thus chronically exacerbate tissue decline. Whereas senescent cells are active targets for anti-ageing therapy(6-11), why these cells form in vivo, how they affect tissue ageing and the effect of their elimination remain unclear(12,13). Here we identify naturally occurring...
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作者:Elvidge, Sean
作者单位:University of Birmingham
摘要:Categorizing geomagnetic storms on a scale of one to five leaves no room for once-a-century superstorms.
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作者:Zernicka-Goetz, Magdalena; Hyun, Insoo
作者单位:California Institute of Technology
摘要:Letter to the Editor
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作者:Wu, Jingjing; Deng, Jue; Theocharidis, Georgios; Sarrafian, Tiffany L.; Griffiths, Leigh G.; Bronson, Roderick T.; Veves, Aristidis; Chen, Jianzhu; Yuk, Hyunwoo; Zhao, Xuanhe
作者单位:Massachusetts Institute of Technology (MIT); Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Joslin Diabetes Center, Inc.; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Mayo Clinic; Mayo Clinic; Harvard University; Harvard Medical School; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要:Implanted biomaterials and devices face compromised functionality and efficacy in the long term owing to foreign body reactions and subsequent formation of fibrous capsules at the implant-tissue interfaces 1-4 . Here we demonstrate that an adhesive implant-tissue interface can mitigate fibrous capsule formation in diverse animal models, including rats, mice, humanized mice and pigs, by reducing the level of infiltration of inflammatory cells into the adhesive implant-tissue interface compared ...
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作者:Dolgin, Elie
摘要:The same mRNA technology that quickly brought the world a vaccine for COVID-19 is now showing promise as a bespoke therapy for cancer.
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作者:Mallapaty, Smriti
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作者:Lane, Julia; Owen-Smith, Jason; Weinberg, Bruce A.
作者单位:New York University; University of Michigan System; University of Michigan; University System of Ohio; Ohio State University
摘要:National statistics systems should recognize the researchers whose ideas drive artificial-intelligence applications, not just machines and factory outputs.