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作者:Ahmad, Wajeeha; Sen, Ananya; Eesley, Charles; Brynjolfsson, Erik
作者单位:Stanford University; Carnegie Mellon University; Stanford University
摘要:The financial motivation to earn advertising revenue has been widely conjectured to be pivotal for the production of online misinformation(1-4). Research aimed at mitigating misinformation has so far focused on interventions at the user level(5-8), with little emphasis on how the supply of misinformation can itself be countered. Here we show how online misinformation is largely financed by advertising, examine how financing misinformation affects the companies involved, and outline interventio...
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作者:Ulvund, Kristine; Nuwer, Rachel
作者单位:Norwegian Institute Nature Research
摘要:Over the past 25 years, Kristine Ulvund has helped to increase the species' population size from 50 or so individuals to more than 500.
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作者:Kulkarni, Sumeet
摘要:Two particular broods of the insects are popping up together for the first time in two centuries, and there's a lot we don't know about them.
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作者:Gribben, Christopher; Galanakis, Vasileios; Calderwood, Alexander; Williams, Eleanor C.; Chazarra-Gil, Ruben; Larraz, Miguel; Frau, Carla; Puengel, Tobias; Guillot, Adrien; Rouhani, Foad J.; Mahbubani, Krishnaa; Godfrey, Edmund; Davies, Susan E.; Athanasiadis, Emmanouil; Saeb-Parsy, Kourosh; Tacke, Frank; Allison, Michael; Mohorianu, Irina; Vallier, Ludovic
作者单位:University of Cambridge; University of Cambridge; Humboldt University of Berlin; Free University of Berlin; Charite Universitatsmedizin Berlin; Berlin Institute of Health; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Humboldt University of Berlin; Free University of Berlin; Charite Universitatsmedizin Berlin; Berlin Institute of Health; Francis Crick Institute; University of Cambridge; University of Cambridge; Cambridge University Hospitals NHS Foundation Trust; Addenbrooke's Hospital; University of Cambridge; Academy of Athens; University of West Attica; Max Planck Society
摘要:For many adult human organs, tissue regeneration during chronic disease remains a controversial subject. Regenerative processes are easily observed in animal models, and their underlying mechanisms are becoming well characterized(1-4), but technical challenges and ethical aspects are limiting the validation of these results in humans. We decided to address this difficulty with respect to the liver. This organ displays the remarkable ability to regenerate after acute injury, although liver rege...
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作者:Matchett, K. P.; Wilson-Kanamori, J. R.; Portman, J. R.; Kapourani, C. A.; Fercoq, F.; May, S.; Zajdel, E.; Beltran, M.; Sutherland, E. F.; Mackey, J. B. G.; Brice, M.; Wilson, G. C.; Wallace, S. J.; Kitto, L.; Younger, N. T.; Dobie, R.; Mole, D. J.; Oniscu, G. C.; Wigmore, S. J.; Ramachandran, P.; Vallejos, C. A.; Carragher, N. O.; Saeidinejad, M. M.; Quaglia, A.; Jalan, R.; Simpson, K. J.; Kendall, T. J.; Rule, J. A.; Lee, W. M.; Hoare, M.; Weston, C. J.; Marioni, J. C.; Teichmann, S. A.; Bird, T. G.; Carlin, L. M.; Henderson, N. C.
作者单位:University of Edinburgh; University of Edinburgh; University of Edinburgh; Beatson Institute; University of Edinburgh; Royal Infirmary of Edinburgh; University of Edinburgh; Karolinska Institutet; Alan Turing Institute; University of Edinburgh; University of London; University College London; University of London; University College London; Royal Free London NHS Foundation Trust; University of London; University College London; University of Edinburgh; University of Texas System; University of Texas Southwestern Medical Center; University of Cambridge; University of Cambridge; University of Birmingham; University of Birmingham; University of Birmingham; Cancer Research UK; University of Cambridge; CRUK Cambridge Institute; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; Wellcome Trust Sanger Institute; University of Cambridge; University of Glasgow; University of Edinburgh
摘要:The liver has a unique ability to regenerate(1,2); however, in the setting of acute liver failure (ALF), this regenerative capacity is often overwhelmed, leaving emergency liver transplantation as the only curative option(3-5). Here, to advance understanding of human liver regeneration, we use paired single-nucleus RNA sequencing combined with spatial profiling of healthy and ALF explant human livers to generate a single-cell, pan-lineage atlas of human liver regeneration. We uncover a novel A...
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作者:Ledford, Heidi
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作者:Plackett, Benjamin
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作者:Cui, Xi-Yang; Li, Zhu; Kong, Ziren; Liu, Yu; Meng, Hao; Wen, Zihao; Wang, Changlun; Chen, Junyi; Xu, Mengxin; Li, Yiyan; Gao, Jingyue; Zhu, Wenjia; Hao, Zhixin; Huo, Li; Liu, Shaoyan; Yang, Zhi; Liu, Zhibo
作者单位:Peking University; Changping Laboratory; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College Hospital; Peking Union Medical College; Peking University
摘要:Targeted radionuclide therapy, in which radiopharmaceuticals deliver potent radionuclides to tumours for localized irradiation, has addressed unmet clinical needs and improved outcomes for patients with cancer1-4. A therapeutic radiopharmaceutical must achieve both sustainable tumour targeting and fast clearance from healthy tissue, which remains a major challenge5,6. A targeted ligation strategy that selectively fixes the radiopharmaceutical to the target protein in the tumour would be an ide...
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作者:Maiolino, Roberto; Scholtz, Jan; Witstok, Joris; Carniani, Stefano; D'Eugenio, Francesco; de Graaff, Anna; Uebler, Hannah; Tacchella, Sandro; Curtis-Lake, Emma; Arribas, Santiago; Bunker, Andrew; Charlot, Stephane; Chevallard, Jacopo; Curti, Mirko; Looser, Tobias J.; Maseda, Michael V.; Rawle, Timothy D.; Rodriguez del Pino, Bruno; Willott, Chris J.; Egami, Eiichi; Eisenstein, Daniel J.; Hainline, Kevin N.; Robertson, Brant; Williams, Christina C.; Willmer, Christopher N. A.; Baker, William M.; Boyett, Kristan; DeCoursey, Christa; Fabian, Andrew C.; Helton, Jakob M.; Ji, Zhiyuan; Jones, Gareth C.; Kumari, Nimisha; Laporte, Nicolas; Nelson, Erica J.; Perna, Michele; Sandles, Lester; Shivaei, Irene; Sun, Fengwu
作者单位:University of Cambridge; University of Cambridge; University of London; University College London; Scuola Normale Superiore di Pisa; Max Planck Society; University of Hertfordshire; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro de Astrobiologia (INTA); University of Oxford; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; European Southern Observatory; University of Wisconsin System; University of Wisconsin Madison; Space Telescope Science Institute; National Research Council Canada; University of Arizona; Smithsonian Institution; University of California System; University of California Santa Cruz; University of Melbourne; University of Cambridge; Space Telescope Science Institute; University of Colorado System; University of Colorado Boulder
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作者:Le, Tian; Pan, Zhiming; Xu, Zhuokai; Liu, Jinjin; Wang, Jialu; Lou, Zhefeng; Yang, Xiaohui; Wang, Zhiwei; Yao, Yugui; Wu, Congjun; Lin, Xiao
作者单位:Westlake University; Westlake University; Westlake University; Westlake University; Beijing Institute of Technology; Beijing Institute of Technology; China Jiliang University; Beijing Institute of Technology; Westlake University
摘要:The interplay among frustrated lattice geometry, non-trivial band topology and correlation yields rich quantum states of matter in kagome systems(1,2). A series of recent members in this family, AV(3)Sb(5) (A=K, Rb or Cs), exhibit a cascade of symmetry-breaking transitions(3), involving the 3Q chiral charge ordering(4-8), electronic nematicity(9,10), roton pair density wave(11) and superconductivity(12). The nature of the superconducting order is yet to be resolved. Here we report an indicatio...