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作者:[Anonymous]
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作者:Hong, Jiani; Tian, Ye; Liang, Tiancheng; Liu, Xinmeng; Song, Yizhi; Guan, Dong; Yan, Zixiang; Guo, Jiadong; Tang, Binze; Cao, Duanyun; Guo, Jing; Chen, Ji; Pan, Ding; Xu, Li-Mei; Wang, En-Ge; Jiang, Ying
作者单位:Peking University; Beijing Institute of Technology; Beijing Normal University; Peking University; Peking University; Hong Kong University of Science & Technology; Hong Kong University of Science & Technology; Peking University; Tsinghua University; Collaborative Innovation Center of Quantum Matter; Peking University
摘要:Ice surfaces are closely relevant to many physical and chemical properties, such as melting, freezing, friction, gas uptake and atmospheric reaction(1-8). Despite extensive experimental and theoretical investigations(9-17), the exact atomic structures of ice interfaces remain elusive owing to the vulnerable hydrogen-bonding network and the complicated premelting process. Here we realize atomic-resolution imaging of the basal (0001) surface structure of hexagonal water ice (ice Ih) by using qPl...
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作者:[Anonymous]
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作者:Hiis, Elisabeth G.; Vick, Silas H. W.; Molstad, Lars; Rosdal, Kristine; Jonassen, Kjell Rune; Winiwarter, Wilfried; Bakken, Lars R.
作者单位:Norwegian University of Life Sciences; International Institute for Applied Systems Analysis (IIASA); University of Zielona Gora
摘要:Farmed soils contribute substantially to global warming by emitting N2O (ref. 1), and mitigation has proved difficult(2). Several microbial nitrogen transformations produce N2O, but the only biological sink for N2O is the enzyme NosZ, catalysing the reduction of N2O to N-2 (ref. 3). Although strengthening the NosZ activity in soils would reduce N2O emissions, such bioengineering of the soil microbiota is considered challenging(4,5). However, we have developed a technology to achieve this, usin...
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作者:Gibney, Elizabeth
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作者:Voloshina, Alexandra S.
作者单位:University of California System; University of California Irvine
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作者:Li, Ning; Yan, Kexin; Rukkijakan, Thanya; Liang, Jiefeng; Liu, Yuting; Wang, Zhipeng; Nie, Heran; Muangmeesri, Suthawan; Castiella-Ona, Gonzalo; Pan, Xuejun; Zhou, Qunfang; Jiang, Guibin; Zhou, Guangyuan; Ralph, John; Samec, Joseph S. M.; Wang, Feng
作者单位:Chinese Academy of Sciences; Dalian Institute of Chemical Physics, CAS; Stockholm University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Research Center for Eco-Environmental Sciences (RCEES), CAS; Shandong University; University of Wisconsin System; University of Wisconsin Madison; University of Wisconsin System; University of Wisconsin Madison
摘要:Lignocellulose is mainly composed of hydrophobic lignin and hydrophilic polysaccharide polymers, contributing to an indispensable carbon resource for green biorefineries(1,2). When chemically treated, lignin is compromised owing to detrimental intra- and intermolecular crosslinking that hampers downstream process(3,4). The current valorization paradigms aim to avoid the formation of new C-C bonds, referred to as condensation, by blocking or stabilizing the vulnerable moieties of lignin(5-7). A...
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作者:Ledford, Heidi
摘要:Researchers in India fought to develop what could have been the first therapy to use gene-editing to halt a rare neurodegenerative disease. The efforts hold lessons for the messy state of modern drug development.
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作者:Aguade-Gorgorio, Julia; Jami-Alahmadi, Yasaman; Calvanese, Vincenzo; Kardouh, Maya; Fares, Iman; Johnson, Haley; Rezek, Valerie; Ma, Feiyang; Magnusson, Mattias; Wang, Yanling; Shin, Juliana E.; Nance, Karina J.; Goodridge, Helen S.; Liebscher, Simone; Schenke-Layland, Katja; Crooks, Gay M.; Wohlschlegel, James A.; Mikkola, Hanna K. A.
作者单位:University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of London; University College London; Institut de Recerca Contra la Leucemia Josep Carreras (IJC); University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Lund University; Cedars Sinai Medical Center; Eberhard Karls University of Tubingen; Eberhard Karls University of Tubingen; UCLA Jonsson Comprehensive Cancer Center; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; Pfizer; Pfizer USA; Oakland University; University of California System; University of California San Francisco; Amgen
摘要:The processes that govern human haematopoietic stem cell (HSC) self-renewal and engraftment are poorly understood and challenging to recapitulate in culture to reliably expand functional HSCs1-3. Here we identify MYC target1 (MYCT1; also known as MTLC) as a crucial human HSC regulator that moderates endocytosis and environmental sensing in HSCs. MYCT1 is selectively expressed in undifferentiated human haematopoietic stem and progenitor cells (HSPCs) and endothelial cells but becomes markedly d...
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作者:Alexander, Denis R.; White, Robert S.
作者单位:University of Cambridge
摘要:Letter to the Editor