2024

最新文章

• Spatially restricted immune and microbiota-driven adaptation of the gut AI翻译
  作者：Mayassi, Toufic; Li, Chenhao; Segerstolpe, Asa; Brown, Eric M.; Weisberg, Rebecca; Nakata, Toru; Yano, Hiroshi; Herbst, Paula; Artis, David; Graham, Daniel B.; Xavier, Ramnik J.
  作者单位：Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine
  摘要：The intestine is characterized by an environment in which host requirements for nutrient and water absorption are consequently paired with the requirements to establish tolerance to the outside environment. To better understand how the intestine functions in health and disease, large efforts have been made to characterize the identity and composition of cells from different intestinal regions(1-8). However, the robustness, nature of adaptability and extent of resilience of the transcriptional ...
• CRISPR patent problems harm Indian farmers AI翻译
  作者：Chaurasia, Anurag
  作者单位：Indian Council of Agricultural Research (ICAR); ICAR - Indian Institute of Vegetable Research
• Claims that dam removals were to blame for Valencia floods are false AI翻译
  作者：de Leaniz, Carlos Garcia; Mouchlianitis, Foivos A.
  作者单位：Universidade de Vigo
• Meet the Latina scientists advancing health and policy AI翻译
  作者：Rodrigues, Meghie
  摘要：Four Latin American researchers reflect on their experiences bridging the gap between science and policy in the region.
• Richard Dawkins's book of the dead is haunted by ghosts of past works AI翻译
  作者：Comfort, Nathaniel
  作者单位：University of California System; University of California Berkeley; Johns Hopkins University
• COFFEE CULTURE: FREQUENT BREWS ALTER GUT MICROBES AI翻译
  作者：[Anonymous]
• Multiple mechanisms for licensing human replication origins AI翻译
  作者：Yang, Ran; Hunker, Olivia; Wise, Marleigh; Bleichert, Franziska
  作者单位：Yale University
  摘要：Loading of replicative helicases is obligatory for the assembly of DNA replication machineries. The eukaryotic MCM2-7 replicative helicase motor is deposited onto DNA by the origin recognition complex (ORC) and co-loader proteins as a head-to-head double hexamer to license replication origins. Although extensively studied in budding yeast(1-4), the mechanisms of origin licensing in multicellular eukaryotes remain poorly defined. Here we use biochemical reconstitution and electron microscopy to...
• Climate and health needs are driving materials advances AI翻译
  作者：Baker, Simon
  摘要：Many of the solutions to global challenges are coming from this expanding field.
• Why Asia is leading the field in green materials AI翻译
  作者：Crow, James Mitchell
  摘要：Finding answers to climate problems - and the financial benefits this might bring - is driving advances.
• Sacrificial capillary pumps to engineer multiscalar biological forms AI翻译
  作者：Sundaram, Subramanian; Lee, Joshua H.; Bjorge, Isabel M.; Michas, Christos; Kim, Sudong; Lammers, Alex; Mano, Joao F.; Eyckmans, Jeroen; White, Alice E.; Chen, Christopher S.
  作者单位：Boston University; Boston University; Harvard University; Universidade de Aveiro; Boston University; Boston University; Boston University
  摘要：Natural tissues are composed of diverse cells and extracellular materials whose arrangements across several length scales-from subcellular lengths(1) (micrometre) to the organ scale(2) (centimetre)-regulate biological functions. Tissue-fabrication methods have progressed to large constructs, for example, through stereolithography(3) and nozzle-based bioprinting(4,5), and subcellular resolution through subtractive photoablation(6-8). However, additive bioprinting struggles with sub-nozzle/voxel...