2025

最新文章

• El Ninos that linger are becoming less of a rarity AI翻译
  作者：[Anonymous]
• Cancer vulnerabilities exposed by finding interactions among DNA repair factors AI翻译
  作者：Siegner, Sebastian M.; Fielden, John
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich
• Seismic imaging of a basaltic Lesser Antilles slab from ancient tectonics AI翻译
  作者：Yang, Xusong; Xie, Yujiang; Rychert, Catherine A.; Harmon, Nicholas; Goes, Saskia; Rietbrock, Andreas; Lynch, Lloyd
  作者单位：Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Geology & Geophysics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Southampton; University of Miami; University of Texas System; University of Texas Austin; Woods Hole Oceanographic Institution; Imperial College London; Helmholtz Association; Karlsruhe Institute of Technology; University West Indies Mona Jamaica; University West Indies Saint Augustine
  摘要：At subduction zones, lithospheric material descends through the upper mantle to the mantle transition zone (MTZ), where it may continue to sink into the lower mantle or stagnate(1,2). Several factors may be important in influencing this flow, including chemical heterogeneity(3,4,5). However, tight constraints on these mantle flows and the exact factors that affect them have proved challenging. We use P-to-S receiver functions to image the subducting slab and the MTZ beneath the Lesser Antilles...
• Are screens harming teens? What scientists can do to find answers AI翻译
  作者：[Anonymous]
• Formation and composition of Earth's Hadean protocrust AI翻译
  作者：Turner, Simon; Wood, Bernard; Johnson, Tim; O'Neill, Craig; Bourdon, Bernard
  作者单位：Macquarie University; University of Oxford; Curtin University; Queensland University of Technology (QUT); Centre National de la Recherche Scientifique (CNRS); Ecole Normale Superieure de Lyon (ENS de LYON); Universite Lyon 1
  摘要：Although Earth, together with other terrestrial planets, must have had an early-formed protocrust, the chemical composition of this crust has received little attention. The protocrust was extracted from an extensive magma ocean formed by accretion and melting of asteroidal bodies1. Both experimental and chronological data suggest that the silicate melt ascending from this magma ocean formed in equilibrium with, or after, metal was extracted to form Earth's core. Here we show that a protocrust ...
• Oxidation of retromer complex controls mitochondrial translation AI翻译
  作者：Zhang, Junbing; Ali, Md Yousuf; Chong, Harrison Byron; Tien, Pei-Chieh; Woods, James; Noble, Carolina; Vornbaumen, Tristan; Ordulu, Zehra; Possemato, Anthony P.; Harry, Stefan; Fonticella, Jay Miguel; Fellah, Lina; Harrison, Drew; Ge, Maolin; Khandelwal, Neha; Huang, Yingfei; Chauvin, Maeva; Bischof, Anica Tamara; Hambelton, Grace Marie; Gohar, Magdy Farag; Zhang, Siwen; Choi, Mingyu; Bouberhan, Sara; Oliva, Esther; Mino-Kenudson, Mari; Pavlova, Natalya N.; Lawrence, Michael; Gainor, Justin F.; Beausoleil, Sean A.; Bardeesy, Nabeel; Mostoslavsky, Raul; Pepin, David; Ott, Christopher J.; Liau, Brian; Bar-Peled, Liron
  作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Chinese Academy of Sciences; Shanghai Institute of Nutrition & Health, CAS; University of Chinese Academy of Sciences, CAS; Harvard University; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Brigham & Women's Hospital; Cell Signaling Technology; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Massachusetts Institute of Technology (MIT); Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Utah System of Higher Education; University of Utah; Huntsman Cancer Institute; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
  摘要：Reactive oxygen species (ROS) underlie human pathologies including cancer and neurodegeneration1,2. However, the proteins that sense ROS levels and regulate their production through their cysteine residues remain ill defined. Here, using systematic base-editing and computational screens, we identify cysteines in VPS35, a member of the retromer trafficking complex3, that phenocopy inhibition of mitochondrial translation when mutated. We find that VPS35 underlies a reactive metabolite-sensing pa...
• How the Atlantic jet stream has changed in 600 years - and what it means for weather AI翻译
  作者：Dannenberg, Matthew P.; Wise, Erika K.
  作者单位：University of Iowa; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine
• How the NIH dominates the world's health research - in charts AI翻译
  作者：Gaind, Nisha
• Hyperbolic phonon-polariton electroluminescence in 2D heterostructures AI翻译
  作者：Guo, Qiushi; Esin, Iliya; Li, Cheng; Chen, Chen; Han, Guanyu; Liu, Song; Edgar, James H.; Zhou, Selina; Demler, Eugene; Refael, Gil; Xia, Fengnian
  作者单位：Yale University; City University of New York (CUNY) System; City University of New York (CUNY) System; California Institute of Technology; California Institute of Technology; Bar Ilan University; Kansas State University; California Institute of Technology; Swiss Federal Institutes of Technology Domain; ETH Zurich
  摘要：Phonon polaritons are quasiparticles resulting from the coherent coupling of photons with optical phonons in polar dielectrics1. Owing to their exceptional ability to confine electric fields to deep-subwavelength scales with low loss, they are uniquely poised to enable a suite of applications beyond the reach of conventional photonics, such as subdiffraction imaging2 and near-field energy transfer3, 4-5. The conventional approach to exciting phonon polaritons through optical methods, however, ...
• Water structure and electric fields at the interface of oil droplets AI翻译
  作者：Shi, Lixue; Lacour, R. Allen; Qian, Naixin; Heindel, Joseph P.; Lang, Xiaoqi; Zhao, Ruoqi; Head-Gordon, Teresa; Min, Wei
  作者单位：Columbia University; University of California System; University of California Berkeley; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley
  摘要：Interfacial water exhibits rich and complex behaviour1, playing an important part in chemistry, biology, geology and engineering. However, there is still much debate on the fundamental properties of water at hydrophobic interfaces, such as orientational ordering, the concentration of hydronium and hydroxide, improper hydrogen bonds and the presence of large electric fields2, 3, 4-5. This controversy arises from the challenges in measuring interfacial systems, even with the most advanced experi...