作者：Beltran, Antoni; Jiang, Xiang'er; Shen, Yue; Lehner, Ben
作者单位：Barcelona Institute of Science & Technology; Pompeu Fabra University; Centre de Regulacio Genomica (CRG); Beijing Genomics Institute (BGI); Beijing Genomics Institute (BGI); Pompeu Fabra University; ICREA; Wellcome Trust Sanger Institute
摘要：Missense variants that change the amino acid sequences of proteins cause one-third of human genetic diseases1. Tens of millions of missense variants exist in the current human population, and the vast majority of these have unknown functional consequences. Here we present a large-scale experimental analysis of human missense variants across many different proteins. Using DNA synthesis and cellular selection experiments we quantify the effect of more than 500,000 variants on the abundance of mo...
作者：Bromley-Trujillo, Rebecca
作者单位：Christopher Newport University
作者：Guo, Yinjie; Pack, Jordan; Swann, Joshua; Holtzman, Luke; Cothrine, Matthew; Watanabe, Kenji; Taniguchi, Takashi; Mandrus, David G.; Barmak, Katayun; Hone, James; Millis, Andrew J.; Pasupathy, Abhay; Dean, Cory R.
作者单位：Columbia University; Columbia University; University of Tennessee System; University of Tennessee Knoxville; National Institute for Materials Science; National Institute for Materials Science; United States Department of Energy (DOE); Oak Ridge National Laboratory; Columbia University; Simons Foundation; Flatiron Institute; United States Department of Energy (DOE); Brookhaven National Laboratory
摘要：The discovery of superconductivity in twisted bilayer and trilayer graphene1, 2, 3, 4-5 has generated tremendous interest. The key feature of these systems is an interplay between interlayer coupling and a moir & eacute; superlattice that gives rise to low-energy flat bands with strong correlations6. Flat bands can also be induced by moir & eacute; patterns in lattice-mismatched and/or twisted heterostructures of other two-dimensional materials, such as transition metal dichalcogenides (TMDs)7...
