2025

最新文章

• Young people are crucial to research - how can they be paid fairly? AI翻译
  作者：D'souza, Nicole Anne; Tisdall, E. Kay M.; Battaglia, Silvia Maria; Ruiz-Casares, Monica
  作者单位：University of Toronto; University of Edinburgh; Toronto Metropolitan University; Toronto Metropolitan University; McGill University
• Africa can't wait for pandemic preparedness AI翻译
  作者：Ndembi, Nicaise; Folayan, Morenike Oluwatoyin
  作者单位：Obafemi Awolowo University
• The new science of menopause: these emerging therapies could change women's health AI翻译
  作者：Peeples, Lynne
• Long-lived entanglement of molecules in magic-wavelength optical tweezers AI翻译
  作者：Ruttley, Daniel K.; Hepworth, Tom R.; Guttridge, Alexander; Cornish, Simon L.
  作者单位：Durham University; Durham University
  摘要：Realizing quantum control and entanglement of particles is crucial for advancing both quantum technologies and fundamental science. Substantial developments in this domain have been achieved in a variety of systems1, 2, 3, 4-5. In this context, ultracold polar molecules offer new and unique opportunities because of their more complex internal structure associated with vibration and rotation, coupled with the existence of long-range interactions6,7. However, the same properties make molecules h...
• All-solid-state Li-S batteries with fast solid-solid sulfur reaction AI翻译
  作者：Song, Huimin; Muench, Konrad; Liu, Xu; Shen, Kaier; Zhang, Ruizhuo; Weintraut, Timo; Yusim, Yuriy; Jiang, Dequan; Hong, Xufeng; Meng, Jiashen; Liu, Yatao; He, Mengxue; Li, Yitao; Henkel, Philip; Brezesinski, Torsten; Janek, Juergen; Pang, Quanquan
  作者单位：Peking University; Justus Liebig University Giessen; Justus Liebig University Giessen; Helmholtz Association; Karlsruhe Institute of Technology
  摘要：With promises for high specific energy, high safety and low cost, the all-solid-state lithium-sulfur battery (ASSLSB) is ideal for next-generation energy storage1, 2, 3, 4-5. However, the poor rate performance and short cycle life caused by the sluggish solid-solid sulfur redox reaction (SSSRR) at the three-phase boundaries remain to be solved. Here we demonstrate a fast SSSRR enabled by lithium thioborophosphate iodide (LBPSI) glass-phase solid electrolytes (GSEs). On the basis of the reversi...
• Structural basis for the conformational protection of nitrogenase from O2 AI翻译
  作者：Narehood, Sarah M.; Cook, Brian D.; Srisantitham, Suppachai; Eng, Vanessa H.; Shiau, Angela A.; Mcguire, Kelly L.; Britt, R. David; Herzik Jr, Mark A.; Tezcan, F. Akif
  作者单位：University of California System; University of California San Diego; University of California System; University of California Davis
  摘要：The low reduction potentials required for the reduction of dinitrogen (N2) render metal-based nitrogen-fixation catalysts vulnerable to irreversible damage by dioxygen (O2)1, 2-3. Such O2 sensitivity represents a major conundrum for the enzyme nitrogenase, as a large fraction of nitrogen-fixing organisms are either obligate aerobes or closely associated with O2-respiring organisms to support the high energy demand of catalytic N2 reduction4. To counter O2 damage to nitrogenase, diazotrophs use...
• Entanglement and iSWAP gate between molecular qubits AI翻译
  作者：Picard, Lewis R. B.; Park, Annie J.; Patenotte, Gabriel E.; Gebretsadkan, Samuel; Wellnitz, David; Rey, Ana Maria; Ni, Kang-Kuen
  作者单位：Harvard University; Harvard University; Harvard University; National Institute of Standards & Technology (NIST) - USA; University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder
  摘要：Quantum computation and simulation rely on long-lived qubits with controllable interactions. Trapped polar molecules have been proposed as a promising quantum computing platform, offering scalability and single-particle addressability while still leveraging inherent complexity and strong couplings of molecules1-5. Recent progress in the single quantum state preparation and coherence of the hyperfine-rotational states of individually trapped molecules allows them to serve as promising qubits6-1...
• Meta AI creates speech-to-speech translator that works in dozens of languages AI翻译
  作者：Castelvecchi, Davide
• Build a DNA database to help identify children stolen in conflicts AI翻译
  作者：Huston, Sara
  作者单位：Ann & Robert H. Lurie Children's Hospital of Chicago
• Engineered extrachromosomal oncogene amplifications promote tumorigenesis AI翻译
  作者：Pradella, Davide; Zhang, Minsi; Gao, Rui; Yao, Melissa A.; Gluchowska, Katarzyna M.; Cendon-Florez, Ylenia; Mishra, Tanmay; La Rocca, Gaspare; Weigl, Moritz; Jiao, Ziqi; Nguyen, Hieu H. M.; Lisi, Marta; Ozimek, Mateusz M.; Mastroleo, Chiara; Chen, Kevin; Grimm, Felix; Luebeck, Jens; Zhang, Shu; Zolli, Andrea Alice; Sun, Eric G.; Dameracharla, Bhargavi; Zhao, Zhengqiao; Pritykin, Yuri; Sigel, Carlie; Chang, Howard Y.; Mischel, Paul S.; Bafna, Vineet; Antonescu, Cristina R.; Ventura, Andrea
  作者单位：Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; University of California System; University of California San Diego; Stanford University; Stanford University; Stanford University; Stanford University; Memorial Sloan Kettering Cancer Center; Rockefeller University; Cornell University; Weill Cornell Medicine; Princeton University; Princeton University; Memorial Sloan Kettering Cancer Center; Howard Hughes Medical Institute; Stanford University; University of California System; University of California San Diego
  摘要：Focal gene amplifications are among the most common cancer-associated mutations1 but have proven challenging to engineer in primary cells and model organisms. Here we describe a general strategy to engineer large (more than 1 Mbp) focal amplifications mediated by extrachromosomal DNAs (ecDNAs)2 in a spatiotemporally controlled manner in cells and in mice. By coupling ecDNA formation with expression of selectable markers, we track the dynamics of ecDNA-containing cells under physiological condi...