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作者:Adli, Mazhar; Przybyla, Laralynne; Burdett, Tony; Burridge, Paul W.; Cacheiro, Pilar; Chang, Howard Y.; Engreitz, Jesse M.; Gilbert, Luke A.; Greenleaf, William J.; Hsu, Li; Huangfu, Danwei; Hung, Ling-Hong; Kundaje, Anshul; Li, Sheng; Parkinson, Helen; Qiu, Xiaojie; Robson, Paul; Schuerer, Stephan C.; Shojaie, Ali; Skarnes, William C.; Smedley, Damian; Studer, Lorenz; Sun, Wei; Vidovic, Dusica; Vierbuchen, Thomas; White, Brian S.; Yeung, Ka Yee; Yue, Feng; Zhou, Ting; MorPhiC Consortium, Neda
作者单位:Ann & Robert H. Lurie Children's Hospital of Chicago; Robert H. Lurie Comprehensive Cancer Center; Northwestern University; Feinberg School of Medicine; University of California System; University of California San Francisco; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; Northwestern University; Feinberg School of Medicine; University of London; Queen Mary University London; Stanford University; Stanford University; Stanford University; University of California System; University of California San Francisco; Fred Hutchinson Cancer Center; Memorial Sloan Kettering Cancer Center; University of Washington; University of Washington Tacoma; Stanford University; Jackson Laboratory; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; University of Miami; University of Washington; University of Washington Seattle; Ann & Robert H. Lurie Children's Hospital of Chicago; Robert H. Lurie Comprehensive Cancer Center; Northwestern University; Feinberg School of Medicine
摘要:Recent advances in functional genomics and human cellular models have substantially enhanced our understanding of the structure and regulation of the human genome. However, our grasp of the molecular functions of human genes remains incomplete and biased towards specific gene classes. The Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Consortium aims to address this gap by creating a comprehensive catalogue of the molecular and cellular phenotypes associated with null alleles of all h...
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作者:Castelvecchi, Davide
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作者:Zhang, Wenqiang; Jiang, Hong; Liu, Yikuan; Hu, Yue; Palakkal, Athulya Surendran; Zhou, Yujie; Sun, Meng; Du, Enping; Gong, Wei; Zhang, Qun; Jiang, Jianwen; Dong, Jinqiao; Liu, Yan; Li, Dehui; Zhu, Yihan; Cui, Yong; Duan, Xiangfeng
作者单位:Shanghai Jiao Tong University; Shanghai Jiao Tong University; Zhejiang University of Technology; Zhejiang University of Technology; Huazhong University of Science & Technology; Huazhong University of Science & Technology; National University of Singapore; Chinese Academy of Sciences; University of Science & Technology of China, CAS; CAS Center for Excellence in Quantum Information & Quantum Physics; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Hefei National Laboratory; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles
摘要:The construction of superlattices with a spatial modulation of chemical compositions allows for the creation of artificial materials with tailorable periodic potential landscapes and tunable electronic and optical properties1, 2, 3, 4-5. Conventional semiconductor superlattices with designable potential modulation in one dimension has enabled high-electron-mobility transistors and quantum-cascade lasers. More recently, a diverse set of superlattices has been constructed through self-assembly o...
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作者:Kalogriopoulos, Nicholas A.; Tei, Reika; Yan, Yuqi; Klein, Peter M.; Ravalin, Matthew; Cai, Bo; Soltesz, Ivan; Li, Yulong; Ting, Alice Y.
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作者:[Anonymous]
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作者:Dowling, Quinton M.; Park, Young-Jun; Fries, Chelsea N.; Gerstenmaier, Neil C.; Ols, Sebastian; Yang, Erin C.; Wargacki, Adam J.; Dosey, Annie; Hsia, Yang; Ravichandran, Rashmi; Walkey, Carl D.; Burrell, Anika L.; Veesler, David; Baker, David; King, Neil P.
作者单位:University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; Howard Hughes Medical Institute
摘要:Discrete protein assemblies ranging from hundreds of kilodaltons to hundreds of megadaltons in size are a ubiquitous feature of biological systems and perform highly specialized functions1,2. Despite remarkable recent progress in accurately designing new self-assembling proteins, the size and complexity of these assemblies has been limited by a reliance on strict symmetry3. Here, inspired by the pseudosymmetry observed in bacterial microcompartments and viral capsids, we developed a hierarchic...
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作者:Cardini, Andrea
作者单位:Universita di Modena e Reggio Emilia
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作者:Shrikanth, Siddarth; Ermgassen, Sophus zu; Bull, Joseph W.
作者单位:University of Oxford
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作者:Brusatte, Stephen L.
作者单位:University of Edinburgh
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作者:Plackett, Benjamin