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作者:Vogt, Eelco T. C.; Weckhuysen, Bert M.
作者单位:Utrecht University
摘要:Fossil fuels-coal, oil and gas-supply most of the world's energy and also form the basis of many products essential for everyday life. Their use is the largest contributor to the carbon dioxide emissions that drive global climate change, prompting joint efforts to find renewable alternatives that might enable a carbon-neutral society by as early as 2050. There are clear paths for renewable electricity to replace fossil-fuel-based energy, but the transport fuels and chemicals produced in oil re...
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作者:Kotrys, Anna V.; Durham, Timothy J.; Guo, Xiaoyan A.; Vantaku, Venkata R.; Parangi, Sareh; Mootha, Vamsi K.
作者单位:Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Massachusetts General Hospital; Howard Hughes Medical Institute; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard Medical School; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital
摘要:Heteroplasmy occurs when wild-type and mutant mitochondrial DNA (mtDNA) molecules co-exist in single cells(1). Heteroplasmy levels change dynamically in development, disease and ageing(2,3), but it is unclear whether these shifts are caused by selection or drift, and whether they occur at the level of cells or intracellularly. Here we investigate heteroplasmy dynamics in dividing cells by combining precise mtDNA base editing (DdCBE)(4) with a new method, SCI-LITE (single-cell combinatorial ind...
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作者:[Anonymous]
摘要:Fluid studded with microscopic magnetic particles can be inserted into the body and later retrieved.
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作者:Chaffin, M. S.; Cangi, E. M.; Gregory, B. S.; Yelle, R. V.; Deighan, J.; Elliott, R. D.; Groller, H.
作者单位:University of Colorado System; University of Colorado Boulder; University of Arizona
摘要:Despite its Earth-like size and source material(1,2), Venus is extremely dry(3,4), indicating near-total water loss to space by means of hydrogen outflow from an ancient, steam-dominated atmosphere(5,6). Such hydrodynamic escape likely removed most of an initial Earth-like 3-km global equivalent layer (GEL) of water but cannot deplete the atmosphere to the observed 3-cm GEL because it shuts down below about 10-100 m GEL(5,7). To complete Venus water loss, and to produce the observed bulk atmos...
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作者:Guo, Shijie; Cai, Zihan; Yang, Yanchao; Ding, Qingyuan
作者单位:Hong Kong Polytechnic University; Nanyang Technological University; North China University of Science & Technology; University of Murcia
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作者:[Anonymous]
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作者:Ide, Kazuki
作者单位:University of Osaka
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作者:Celiker, Hikmet; Dehaene, Wim; Myny, Kris
作者单位:KU Leuven; Interuniversity Microelectronics Centre
摘要:Flexible and large-area electronics rely on thin-film transistors (TFTs) to make displays(1-3), large-area image sensors(4-6), microprocessors(7-11), wearable healthcare patches(12-15), digital microfluidics(16,17) and more. Although silicon-based complementary metal-oxide-semiconductor (CMOS) chips are manufactured using several dies on a single wafer and the multi-project wafer concept enables the aggregation of various CMOS chip designs within the same die, TFT fabrication is currently lack...
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作者:Siday, T.; Hayes, J.; Schiegl, F.; Sandner, F.; Menden, P.; Bergbauer, V.; Zizlsperger, M.; Nerreter, S.; Lingl, S.; Repp, J.; Wilhelm, J.; Huber, M. A.; Gerasimenko, Y. A.; Huber, R.
作者单位:University of Regensburg; University of Regensburg
摘要:Bringing optical microscopy to the shortest possible length and time scales has been a long-sought goal, connecting nanoscopic elementary dynamics with the macroscopic functionalities of condensed matter. Super-resolution microscopy has circumvented the far-field diffraction limit by harnessing optical nonlinearities1. By exploiting linear interaction with tip-confined evanescent light fields2, near-field microscopy3,4 has reached even higher resolution, prompting a vibrant research field by e...
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作者:[Anonymous]