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作者:Parreno, V.; Loubiere, V.; Schuettengruber, B.; Fritsch, L.; Rawal, C. C.; Erokhin, M.; Gyorffy, B.; Normanno, D.; Di Stefano, M.; Moreaux, J.; Butova, N. L.; Chiolo, I.; Chetverina, D.; Martinez, A-M; Cavalli, G.
作者单位:Universite de Montpellier; Centre National de la Recherche Scientifique (CNRS); Vienna Biocenter (VBC); Research Institute of Molecular Pathology (IMP); University of Southern California; Russian Academy of Sciences; Institute of Gene Biology (IGB) of Russian Academy of Sciences; Semmelweis University; University of Pecs; Universite de Montpellier; CHU de Montpellier; Universite de Montpellier
摘要:Although cancer initiation and progression are generally associated with the accumulation of somatic mutations(1,2), substantial epigenomic alterations underlie many aspects of tumorigenesis and cancer susceptibility(36) , suggesting that genetic mechanisms might not be the only drivers of malignant transformation(7). However, whether purely non-genetic mechanisms are sufcient to initiate tumorigenesis irrespective of mutations has been unknown. Here, we show that a transient perturbation of t...
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作者:Swain, Anshuman; Woodhouse, Adam; Fagan, William F.; Fraass, Andrew J.; Lowery, Christopher M.
作者单位:Harvard University; Harvard University; Smithsonian Institution; Smithsonian National Museum of Natural History; University System of Maryland; University of Maryland College Park; University of Texas System; University of Texas Austin; University of Bristol; University of Victoria
摘要:In palaeontological studies, groups with consistent ecological and morphological traits across a clade's history (functional groups)(1) afford different perspectives on biodiversity dynamics than do species and genera(2,3), which are evolutionarily ephemeral. Here we analyse Triton, a global dataset of Cenozoic macroperforate planktonic foraminiferal occurrences(4), to contextualize changes in latitudinal equitability gradients(1), functional diversity, palaeolatitudinal specialization and com...
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作者:Karamlou, Amir H.; Rosen, Ilan T.; Muschinske, Sarah E.; Barrett, Cora N.; Di Paolo, Agustin; Ding, Leon; Harrington, Patrick M.; Hays, Max; Das, Rabindra; Kim, David K.; Niedzielski, Bethany M.; Schuldt, Meghan; Serniak, Kyle; Schwartz, Mollie E.; Yoder, Jonilyn L.; Gustavsson, Simon; Yanay, Yariv; Grover, Jeffrey A.; Oliver, William D.
作者单位:Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Wellesley College; Massachusetts Institute of Technology (MIT); Lincoln Laboratory
摘要:Entanglement and its propagation are central to understanding many physical properties of quantum systems(1-3). Notably, within closed quantum many-body systems, entanglement is believed to yield emergent thermodynamic behaviour(4-7). However, a universal understanding remains challenging owing to the non-integrability and computational intractability of most large-scale quantum systems. Quantum hardware platforms provide a means to study the formation and scaling of entanglement in interactin...
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作者:Reardon, Sara
摘要:Scientists worry that the H5N1 strain of avian influenza will become endemic in cattle, which would aid its spread in people.
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作者:Kozlov, Max
摘要:New policy on high-risk biology studies aims to address criticism that previous rules were too vague.
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作者:Brlik, Vojtech
作者单位:Charles University Prague
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作者:Argaw-Denboba, Ayele; Schmidt, Thomas S. B.; Di Giacomo, Monica; Ranjan, Bobby; Devendran, Saravanan; Mastrorilli, Eleonora; Lloyd, Catrin T.; Pugliese, Danilo; Paribeni, Violetta; Dabin, Juliette; Pisaniello, Alessandra; Espinola, Sergio; Crevenna, Alvaro; Ghosh, Subhanita; Humphreys, Neil; Boruc, Olga; Sarkies, Peter; Zimmermann, Michael; Bork, Peer; Hackett, Jamie A.
作者单位:European Molecular Biology Laboratory (EMBL); European Molecular Biology Laboratory (EMBL); University of Oxford; University of Wurzburg; Yonsei University
摘要:The gut microbiota operates at the interface of host-environment interactions to influence human homoeostasis and metabolic networks 1-4 . Environmental factors that unbalance gut microbial ecosystems can therefore shape physiological and disease-associated responses across somatic tissues 5-9 . However, the systemic impact of the gut microbiome on the germline-and consequently on the F1 offspring it gives rise to-is unexplored 10 . Here we show that the gut microbiota act as a key interface b...
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作者:Knaut, C. M.; Suleymanzade, A.; Wei, Y. -C.; Assumpcao, D. R.; Stas, P. -J.; Huan, Y. Q.; Machielse, B.; Knall, E. N.; Sutula, M.; Baranes, G.; Sinclair, N.; De-Eknamkul, C.; Levonian, D. S.; Bhaskar, M. K.; Park, H.; Loncar, M.; Lukin, M. D.
作者单位:Harvard University; Harvard University; Massachusetts Institute of Technology (MIT); Harvard University
摘要:A key challenge in realizing practical quantum networks for long-distance quantum communication involves robust entanglement between quantum memory nodes connected by fibre optical infrastructure(1-3). Here we demonstrate a two-node quantum network composed of multi-qubit registers based on silicon-vacancy (SiV) centres in nanophotonic diamond cavities integrated with a telecommunication fibre network. Remote entanglement is generated by the cavity-enhanced interactions between the electron sp...
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作者:Nordling, Linda; Tanshi, Iroro
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作者:Thomas, Philip; Ruscio, Leonardo; Morin, Olivier; Rempe, Gerhard
作者单位:Max Planck Society
摘要:Entanglement has evolved from an enigmatic concept of quantum physics to a key ingredient of quantum technology. It explains correlations between measurement outcomes that contradict classical physics and has been widely explored with small sets of individual qubits. Multi-partite entangled states build up in gate-based quantum-computing protocols and-from a broader perspective-were proposed as the main resource for measurement-based quantum-information processing(1,2). The latter requires the...