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作者:Donahue, Margaret M.; Colgin, Laura Lee
作者单位:University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin
摘要:Certain neurons encode memories of events that occurred in specific physical locations known as place fields. Chickadees show patterns of neuronal activity that are specific to locations of hidden food but independent of place fields.
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作者:Han, Juntai; Liu, Ziwei; Woods, Ross; Mcvicar, Tim R.; Yang, Dawen; Wang, Taihua; Hou, Ying; Guo, Yuhan; Li, Changming; Yang, Yuting
作者单位:Tsinghua University; University of Bristol; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Environment
摘要:Climate warming induces shifts from snow to rain in cold regions1, altering snowpack dynamics with consequent impacts on streamflow that raise challenges to many aspects of ecosystem services2-4. A straightforward conceptual model states that as the fraction of precipitation falling as snow (snowfall fraction) declines, less solid water is stored over the winter and both snowmelt and streamflow shift earlier in season. Yet the responses of streamflow patterns to shifts in snowfall fraction rem...
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作者:Izzo, Franco; Myers, Robert M.; Ganesan, Saravanan; Mekerishvili, Levan; Kottapalli, Sanjay; Prieto, Tamara; Eton, Elliot O.; Botella, Theo; Dunbar, Andrew J.; Bowman, Robert L.; Sotelo, Jesus; Potenski, Catherine; Mimitou, Eleni P.; Stahl, Maximilian; El Ghaity-Beckley, Sebastian; Arandela, JoAnn; Raviram, Ramya; Choi, Daniel C.; Hoffman, Ronald; Chaligne, Ronan; Abdel-Wahab, Omar; Smibert, Peter; Ghobrial, Irene M.; Scandura, Joseph M.; Marcellino, Bridget; Levine, Ross L.; Landau, Dan A.
作者单位:Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; Cornell University; Weill Cornell Medicine; Rockefeller University; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; Icahn School of Medicine at Mount Sinai; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Icahn School of Medicine at Mount Sinai; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Memorial Sloan Kettering Cancer Center
摘要:In somatic tissue differentiation, chromatin accessibility changes govern priming and precursor commitment towards cellular fates(1-3). Therefore, somatic mutations are likely to alter chromatin accessibility patterns, as they disrupt differentiation topologies leading to abnormal clonal outgrowth. However, defining the impact of somatic mutations on the epigenome in human samples is challenging due to admixed mutated and wild-type cells. Here, to chart how somatic mutations disrupt epigenetic...
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作者:Drew, Liam
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作者:Schattner, Elaine
作者单位:Cornell University; Weill Cornell Medicine
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作者:[Anonymous]
摘要:All around the world, people are pushing back against racism, gender bias and other forms of discrimination to make a positive difference. Our series will tell their stories and highlight their achievements.
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作者:[Anonymous]
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作者:Adam, Jose M.; Makoond, Nirvan; Riveiro, Belen; Buitrago, Manuel
作者单位:Universitat Politecnica de Valencia; Universidade de Vigo
摘要:Hundreds of millions of people cross deficient bridges each day. With damage to these structures likely to intensify because of climate change and ageing, technicians and policymakers must act to make them safer.
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作者:Kozlov, Max
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作者:Govind, Bala; Tapen, Thomas; Apsel, Alyssa
作者单位:Cornell University