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作者:Neupane, Sujaya; Fiete, Ila; Jazayeri, Mehrdad
作者单位:Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要:A cognitive map is a suitably structured representation that enables novel computations using previous experience; for example, planning a new route in a familiar space1. Work in mammals has found direct evidence for such representations in the presence of exogenous sensory inputs in both spatial2,3 and non-spatial domains4-10. Here we tested a foundational postulate of the original cognitive map theory1,11: that cognitive maps support endogenous computations without external input. We recorde...
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作者:Garaude, Simon; Marone, Romina; Lepore, Rosalba; Devaux, Anna; Beerlage, Astrid; Seyres, Denis; Dell' Aglio, Alessandro; Juskevicius, Darius; Zuin, Jessica; Burgold, Thomas; Wang, Sisi; Katta, Varun; Manquen, Garret; Li, Yichao; Larrue, Clement; Camus, Anna; Durzynska, Izabela; Wellinger, Lisa C.; Kirby, Ian; Van Berkel, Patrick H.; Kunz, Christian; Tamburini, Jerome; Bertoni, Francesco; Widmer, Corinne C.; Tsai, Shengdar Q.; Simonetta, Federico; Urlinger, Stefanie; Jeker, Lukas T.
作者单位:University of Basel; University of Basel; University of Basel; University of Basel; University of Basel; University of Geneva; St Jude Children's Research Hospital; University of Geneva; Institute of Oncology Research (IOR); Universita della Svizzera Italiana; Institute of Oncology Research (IOR); University of Basel; Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS); Universite de Toulouse; Universite Toulouse III - Paul Sabatier
摘要:Haematopoietic stem cell (HSC) transplantation (HSCT) is the only curative treatment for a broad range of haematological malignancies, but the standard of care relies on untargeted chemotherapies and limited possibilities to treat malignant cells after HSCT without affecting the transplanted healthy cells(1). Antigen-specific cell-depleting therapies hold the promise of much more targeted elimination of diseased cells, as witnessed in the past decade by the revolution of clinical practice for ...
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作者:Verspoor, Karin
作者单位:Royal Melbourne Institute of Technology (RMIT); University of Melbourne
摘要:The number of errors produced by an LLM can be reduced by grouping its outputs into semantically similar clusters. Remarkably, this task can be performed by a second LLM, and the method's efficacy can be evaluated by a third. Confabulations detected by clustering semantically similar LLM responses.
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作者:Finkel, Yaara; Nachshon, Aharon; Aharon, Einav; Arazi, Tamar; Simonovsky, Elena; Dobesova, Martina; Saud, Zack; Gluck, Avi; Fisher, Tal; Stanton, Richard J.; Schwartz, Michal; Stern-Ginossar, Noam
作者单位:Weizmann Institute of Science; Cardiff University
摘要:Genetic screens have transformed our ability to interrogate cellular factor requirements for viral infections(1,2), but most current approaches are limited in their sensitivity, biased towards early stages of infection and provide only simplistic phenotypic information that is often based on survival of infected cells(2-4). Here, by engineering human cytomegalovirus to express single guide RNA libraries directly from the viral genome, we developed virus-encoded CRISPR-based direct readout scre...
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作者:[Anonymous]
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作者:Amontree, Jacob; Yan, Xingzhou; DiMarco, Christopher S.; Levesque, Pierre L.; Adel, Tehseen; Pack, Jordan; Holbrook, Madisen; Cupo, Christian; Wang, Zhiying; Sun, Dihao; Biacchi, Adam J.; Wilson-Stokes, Charlezetta E.; Watanabe, Kenji; Taniguchi, Takashi; Dean, Cory R.; Hight Walker, Angela R.; Barmak, Katayun; Martel, Richard; Hone, James
作者单位:Columbia University; Universite de Montreal; Universite de Montreal; National Institute of Standards & Technology (NIST) - USA; Columbia University; National Institute of Standards & Technology (NIST) - USA; Howard University; National Institute for Materials Science; Columbia University
摘要:Chemical vapour deposition (CVD) synthesis of graphene on copper has been broadly adopted since the first demonstration of this process(1). However, widespread use of CVD-grown graphene for basic science and applications has been hindered by challenges with reproducibility(2) and quality(3). Here we identify trace oxygen as a key factor determining the growth trajectory and quality for graphene grown by low-pressure CVD. Oxygen-free chemical vapour deposition (OF-CVD) synthesis is fast and hig...
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作者:Tong, J.; Fu, Y.; Domaretskiy, D.; Della Pia, F.; Dagar, P.; Powell, L.; Bahamon, D.; Huang, S.; Xin, B.; Costa Filho, R. N.; Vega, L. F.; Grigorieva, I. V.; Peeters, F. M.; Michaelides, A.; Lozada-Hidalgo, M.
作者单位:University of Manchester; University of Manchester; University of Cambridge; Khalifa University of Science & Technology; Khalifa University of Science & Technology; Khalifa University of Science & Technology; Universidade Federal do Ceara; University of Antwerp
摘要:The basal plane of graphene can function as a selective barrier that is permeable to protons 1,2 but impermeable to all ions 3,4 and gases 5,6 , stimulating its use in applications such as membranes 1,2,7,8 , catalysis 9,10 and isotope separation 11,12 . Protons can chemically adsorb on graphene and hydrogenate it 13,14 , inducing a conductor-insulator transition that has been explored intensively in graphene electronic devices 13-17 . However, both processes face energy barriers 1,12,18 and v...
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作者:Verspoor, Karin
作者单位:Royal Melbourne Institute of Technology (RMIT); University of Melbourne
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作者:Cai, Chen; Chen, Qi
作者单位:Utah System of Higher Education; University of Utah; Utah System of Higher Education; University of Utah
摘要:DNA from organelles called mitochondria is not inherited from the father. But mitochondrial RNAs that sense paternal diet and mitochondrial quality are delivered from sperm to egg, affecting offspring metabolism.
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作者:Nerini, Francesco Fuso; Mazzucato, Mariana; Rockstroem, Johan; van Asselt, Harro; Hall, Jim W.; Matos, Stelvia; Persson, Asa; Sovacool, Benjamin; Vinuesa, Ricardo; Sachs, Jeffrey
作者单位:Royal Institute of Technology; Royal Institute of Technology; University of London; University College London; University of London; University College London; Potsdam Institut fur Klimafolgenforschung; University of Cambridge; University of Oxford; University of Surrey; University of Surrey; Stockholm Environment Institute; Linkoping University; Boston University; Royal Institute of Technology; Royal Institute of Technology; Columbia University
摘要:The world should redouble its efforts on the SDGs, not abandon them. Here's how to progress the United Nations' agenda towards 2050.