8091期

最新文章

• Operating two exchange-only qubits in parallel AI翻译
  作者：Madzik, Mateusz T.; Luthi, Florian; Guerreschi, Gian Giacomo; Mohiyaddin, Fahd A.; Borjans, Felix; Chadwick, Jason D.; Curry, Matthew J.; Ziegler, Joshua; Atanasov, Sarah; Bavdaz, Peter L.; Connors, Elliot J.; Corrigan, J.; Ercan, H. Ekmel; Flory, Robert; George, Hubert C.; Harpt, Benjamin; Henry, Eric; Islam, Mohammad M.; Khammassi, Nader; Keith, Daniel; Lampert, Lester F.; Mladenov, Todor M.; Morris, Randy W.; Nethwewala, Aditi; Neyens, Samuel; Otten, Rene; Osuna Ibarra, Linda P.; Patra, Bishnu; Pillarisetty, Ravi; Premaratne, Shavindra; Ramsey, Mick; Risinger, Andrew; Rooney, John D.; Savytskyy, Rostyslav; Watson, Thomas F.; Zietz, Otto K.; Matsuura, Anne Y.; Pellerano, Stefano; Bishop, Nathaniel C.; Roberts, Jeanette; Clarke, James S.
  作者单位：Intel Corporation; Intel USA
  摘要：Semiconductors are among the most promising platforms to implement large-scale quantum computers, as advanced manufacturing techniques allow fabrication of large quantum dot arrays1. Various qubit encodings can be used to store and manipulate quantum information on these quantum dot arrays. Regardless of qubit encoding, precise control over the exchange interaction between electrons confined in quantum dots in the array is critical. Furthermore, it is necessary to execute high-fidelity quantum...
• Proteotoxic stress response drives T cell exhaustion and immune evasion AI翻译
  作者：Wang, Yi; Ma, Anjun; Song, No-Joon; Shannon, Ariana E.; Amankwah, Yaa S.; Chen, Xingyu; Wu, Weidong; Wang, Ziyu; Saadey, Abbey A.; Yousif, Amir; Ghosh, Gautam; Mandula, Jay K.; Velegraki, Maria; Xiao, Tong; Wen, Haitao; Huang, Stanley Ching-Cheng; Wang, Ruoning; Beusch, Christian M.; Dawood, Abdelhameed S.; Gordon, David E.; Abdel-Hakeem, Mohamed S.; Ghoneim, Hazem E.; Xin, Gang; Searle, Brian C.; Li, Zihai
  作者单位：James Cancer Hospital & Solove Research Institute; University System of Ohio; Ohio State University; University System of Ohio; Ohio State University; Johns Hopkins University; University System of Ohio; Ohio State University; University System of Ohio; Ohio State University; Nationwide Childrens Hospital; Research Institute at Nationwide Children's Hospital; Center for Childhood Cancer & Blood Diseases; Emory University; Uppsala University; University System of Ohio; Ohio State University
  摘要：Chronic infections and cancer cause T cell dysfunction known as exhaustion. This cell state is caused by persistent antigen exposure, suboptimal co-stimulation and a plethora of hostile factors that dampen protective immunity and limit the efficacy of immunotherapies1, 2, 3-4. The mechanisms that underlie T cell exhaustion remain poorly understood. Here we analyse the proteome of CD8+ exhausted T (Tex) cells across multiple states of exhaustion in the context of both chronic viral infections a...
• Wildfire smoke exposure and mortality burden in the USA under climate change AI翻译
  作者：Qiu, Minghao; Li, Jessica; Gould, Carlos F.; Jing, Renzhi; Kelp, Makoto; Childs, Marissa L.; Wen, Jeff; Xie, Yuanyu; Lin, Meiyun; Kiang, Mathew V.; Heft-Neal, Sam; Diffenbaugh, Noah S.; Burke, Marshall
  作者单位：State University of New York (SUNY) System; Stony Brook University; State University of New York (SUNY) System; Stony Brook University; Stanford University; Stanford University; Stanford University; University of California System; University of California San Diego; Stanford University; Stanford University; Stanford Medicine; University of Washington; University of Washington Seattle; Princeton University; National Oceanic Atmospheric Admin (NOAA) - USA; Stanford Medicine; Stanford University; National Bureau of Economic Research
  摘要：Wildfire activity has increased in the USA and is projected to accelerate under future climate change1, 2-3. However, our understanding of the impacts of climate change on wildfire activity, smoke and health outcomes remains highly uncertain because of the difficulty of modelling the causal chain from climate to wildfire to air pollution and health. Here we quantify the mortality burden in the USA due to wildfire smoke fine particulate matter (PM2.5) under climate change. We construct an ensem...
• Universities must help students faced with the death of a supervisor AI翻译
  作者：Zarraga-Vargas, Laura
• The origin of male seahorses' brood pouch AI翻译
  作者：[Anonymous]
• Deaminative cross-coupling of amines by boryl radical β-scission AI翻译
  作者：Zhang, Zhenhua; Lonardi, Giovanni; Sephton, Thomas; Guersoy, Yusuf C.; Stavagna, Chiara; Lenardon, Giovanni V. A.; Bietti, Massimo; Leonori, Daniele
  作者单位：RWTH Aachen University; University of Rome Tor Vergata
  摘要：Amines are among the most common functional groups in biologically active molecules and pharmaceuticals1, 2-3, yet they are almost universally treated as synthetic end points4. Here we report a strategy that repositions native primary, secondary and tertiary amines as handles for cross-coupling. The platform relies on in situ activation through borane coordination and exploits a copper catalytic redox system that generates amine-ligated boryl radicals, which undergo beta-scission across the C(...
• Detection of triboelectric discharges during dust events on Mars AI翻译
  作者：Chide, Baptiste; Lorenz, Ralph D.; Montmessin, Franck; Maurice, Sylvestre; Parot, Yann; Hueso, Ricardo; Martinez, German; Vicente-Retortillo, Alvaro; Jacob, Xavier; Lemmon, Mark; Dubois, Bruno; Meslin, Pierre-Yves; Newman, Claire; Bertrand, Tanguy; Deprez, Gregoire; Toledo, Daniel; Sanchez-Lavega, Agustin; Cousin, Agnes; Wiens, Roger C.
  作者单位：Centre National de la Recherche Scientifique (CNRS); Centre National d'Etudes Spatiales (CNES); Universite de Toulouse (EPE); Communaute d'universites et etablissements de Toulouse (Comue); Johns Hopkins University; Johns Hopkins University Applied Physics Laboratory; Universite Paris Saclay; Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); University of Basque Country; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro de Astrobiologia (INTA); Communaute d'universites et etablissements de Toulouse (Comue); Centre National de la Recherche Scientifique (CNRS); Universite de Toulouse (EPE); Institut National Polytechnique de Toulouse; CNRS - Institute of Physics (INP); Universite de Toulouse (EPE); Communaute d'universites et etablissements de Toulouse (Comue); Ulster University; Sorbonne Universite; Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); CY Cergy Paris Universite; Universite PSL; Observatoire de Paris; European Space Agency; European Space Research & Technology Centre; Purdue University System; Purdue University
  摘要：Lightning is among the most energetic manifestation of electrical activity in planetary atmospheres, with documented observations not only on Earth but also on Saturn and Jupiter1. On Mars, the existence of electrical activity has long been suspected2,3 but never directly demonstrated. The dusty atmosphere of Mars undergoes aeolian processes, ranging from wind-blown dust and sand, metre-to-hundred-metre-sized dust devils to thousand-kilometre-scale dust storms4, which, in Earth's deserts, can ...
• 'Tiny' AI model beats massive LLMs at logic test AI翻译
  作者：Gibney, Elizabeth
• George Smoot obituary: Charismatic cosmologist who revealed ripples in the Big Bang's afterglow AI翻译
  作者：Scott, Douglas; Silk, Joseph; Broadhurst, Tom
  作者单位：University of British Columbia; Sorbonne Universite; Johns Hopkins University; University of Basque Country
• Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche (vol 557, pg 714, 2018) AI翻译
  作者：Baghdadi, Meryem B.; Castel, David; Machado, Leo; Fukada, So-ichiro; Birk, David E.; Relaix, Frederic; Tajbakhsh, Shahragim; Mourikis, Philippos