8091期

最新文章

• Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death AI翻译
  作者：Zakharov, Pavel N.; Chowdhury, Chanchal S.; Peterson, Orion J.; Barron, Brady; Vomund, Anthony N.; Gorvel, Laurent; Unanue, Emil R.; Klechevsky, Eynav; Wan, Xiaoxiao; Ravichandran, Kodi S.
  作者单位：Washington University (WUSTL); Flanders Institute for Biotechnology (VIB); Ghent University; Ghent University
  摘要：The primary driver of type I diabetes is the autoimmune T cells that destroy insulin-producing beta-cells within the islets of Langerhans in the pancreas1. Pancreatic islet macrophages have also been variably linked to disease onset and progression. As macrophage-mediated removal of dying cells through efferocytosis regulates tissue homeostasis and immune responses2, here we investigated how efferocytosis by intra-islet macrophages influences the immune environment of pancreatic islets. Using ...
• On Natural Capital: The Value of the World Around Us AI翻译
  作者：Hochard, Jacob
• Chile must preserve international science in Antarctica AI翻译
  作者：Galban Malagon, Cristobal; Leppe, Marcelo; Chiang, Gustavo; Bahamonde, Paulina
  作者单位：Universidad Mayor; Universidad Mayor
• The oldest known lepidosaur and origins of lepidosaur feeding adaptations (10 Sept, 10.1038/s41586-025-09496-9, 2025) AI翻译
  作者：Marke, Daniel; Whiteside, David I.; Sethapanichsakul, Thitiwoot; Coram, Robert A.; Fernandez, Vincent; Liptak, Alexander; Newham, Elis; Benton, Michael J.
  作者单位：University of Bristol; University of Edinburgh; Natural History Museum London; University of London; University College London; European Synchrotron Radiation Facility (ESRF); Diamond Light Source; University of London; Queen Mary University London; University of London; Queen Mary University London
• Radiation-induced amphiregulin drives tumour metastasis (vol 643, pg 810, 2025) AI翻译
  作者：Piffko, Andras; Yang, Kaiting; Panda, Arpit; Heide, Janna; Tesak, Krystyna; Wen, Chuangyu; Zawieracz, Katarzyna; Wang, Liangliang; Naccasha, Emile Z.; Bugno, Jason; Fu, Yanbin; Chen, Dapeng; Donle, Leonhard; Lengyel, Ernst; Tilley, Douglas G.; Mack, Matthias; Rock, Ronald S.; Chmura, Steven J.; Vokes, Everett E.; He, Chuan; Pitroda, Sean P.; Liang, Hua Laura; Weichselbaum, Ralph R.
• Lack of funding is pushing research in Romania to extinction AI翻译
  作者：Pintilie, Lucian
  作者单位：National Institute of Materials Physics - Romania
• Photocatalytic oxygen-atom transmutation of oxetanes AI翻译
  作者：Zhang, Ying-Qi; Li, Shuo-Han; Zhang, Xinglong; Koh, Ming Joo
  作者单位：National University of Singapore; Chinese University of Hong Kong
  摘要：Non-aromatic heterocycles and carbocycles form the skeleton of countless bioactive and functional molecules1,2. Of note, four-membered saturated cyclic molecules such as azetidines, thietanes and cyclobutanes have garnered increasing attention in medicinal chemistry3, 4, 5, 6-7. These molecules often have physicochemical properties relevant to drug discovery: potency, stability, metabolic stability and target specificity3. The replacement of oxygen atoms in readily available oxetanes would off...
• Shadow scholars: inside Kenya's multibillion-dollar fake-essay industry AI翻译
  作者：McKie, Anna
• Don't scrap climate COPs, reform them AI翻译
  作者：Ramakrishna, Kilaparti
  作者单位：Woods Hole Oceanographic Institution
• My funding applications are taking up too much time. How can I stay focused on my research? AI翻译
  作者：You, Xiaoying