6791期

最新文章

• International conferences must include China AI翻译
  作者：Ma, Yifang; Shen, Yinan; Rao, Hai
  作者单位：Southern University of Science & Technology; Southern University of Science & Technology
• Ancient rocks reveal early plate motions: Earth had variable tectonic plate motions and a strong, stable magnetic field 3.5 billion years ago AI翻译
  作者：Nichols, Claire
  作者单位：University of Oxford
• A neuroimmune circuit links stress to skin inflammation AI翻译
  作者：Gaudenzio, Nicolas; Basso, Lilian
  作者单位：Centre National de la Recherche Scientifique (CNRS); Communaute d'universites et etablissements de Toulouse (Comue); Universite de Toulouse (EPE); Institut National de la Sante et de la Recherche Medicale (Inserm)
• Humans share acoustic preferences with other animals AI翻译
  作者：James, Logan S.; Woolley, Sarah C.; Sakata, Jon T.; Hilton, Courtney B.; Ryan, Michael J.; Mehr, Samuel A.
  作者单位：McGill University; University of Texas System; University of Texas Austin; Smithsonian Institution; Smithsonian Tropical Research Institute; Yale University; University of Melbourne; University of Auckland; Universite de Montreal
  摘要：Many animals produce courtship sounds, and receivers prefer some sounds over others. Shared ancestry and convergent evolution may generate similarities in preference across species and underlie Darwin's conjecture that some animals have nearly the same taste for the beautiful as we have. In this study, we show that humans share acoustic preferences with a range of animals, that the strength of human preferences correlates with that in other animals, and that humans respond faster when in agree...
• Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness AI翻译
  作者：Goldman, Michael A.
  作者单位：California State University System; San Francisco State University
• Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors AI翻译
  作者：Wang, Qin; Chen, Ziqi; Zhang, Guorong; Yang, Jiale; Hu, Runfan; Yao, Tongyue; Zeng, Cici; Zhang, Shugeng; Jiang, Wei; Zhu, Shu; Wang, Yucai
  作者单位：Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS
  摘要：In vivo delivery systems (IDSs) are designed to protect and transport therapeutics, but their clinical applications are hindered by low delivery efficiency. We identified gut microbiota as key regulators of efficacy of IDS-based therapies and that disrupting commensal-host interactions markedly improves drug and gene delivery. Intestinal epithelial cells sense microbial stimulation and remotely activate Kupffer cells through serotonin production, thereby driving hepatic IDS clearance. Transien...
• Cross- and branched-selective hydroalkenylation by metal hydride selection AI翻译
  作者：Li, Chunyu; Gan, Xu-cheng; Irie, Yu; Smith, Milo A.; Shenvi, Ryan A.
  作者单位：Scripps Research Institute; Scripps Research Institute; University of Tokyo; Nanjing University
  摘要：Controlled placement of branch points along carbon chains is a core capability in the synthesis of materials, agrochemicals, and pharmaceuticals. Metal hydride hydrogen atom transfer (MHAT) to alkenes represents a valuable elementary step because it accesses branched products directly from abundant alpha-olefins. MHAT catalysis can also be coupled to secondary transition metal catalytic cycles that would otherwise deliver nonbranched (linear) products. However, the hydridic reagents used in MH...
• Complex mesoscale landscapes beneath Antarctica mapped from space (Jan, 10.1126/science.aeh0795, 2026) AI翻译
  作者：Ockenden, H.
• Paleomagnetic detection of relative plate motions and an infrequently reversing core dynamo at 3.5 Ga AI翻译
  作者：Brenner, Alec R.; Fu, Roger R.; Foley, Bradford J.; Lourenco, Diogo L.; Palma-Gomez, Jasmine; Gong, Zheng; Steele, Sarah C.; Li, Joanna; Flannery, David T.; Brown, Adrian J.; Hodgin, Eben B.
  作者单位：Harvard University; Yale University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Swiss Federal Institutes of Technology Domain; ETH Zurich; Smith College; Rice University; Queensland University of Technology (QUT); Brown University
  摘要：Whether early Earth had a mobile lithosphere and plate tectonics is debated. We present paleomagnetic data quantifying differential motion between lithospheric blocks at similar to 3.48 billion years ago (Ga). This manifested as 47(-35)(+69) centimeters per year latitudinal motion of the East Pilbara Craton (Western Australia) across high latitudes, whereas the Barberton Greenstone Belt (South Africa) was stationary at low latitudes. Comparison of this plate motion with candidate analogs sugge...
• A sympathetic-eosinophil axis orchestrates psychological stress to exacerbate skin inflammation AI翻译
  作者：Tian, Jiahe; Cao, Yudian; Li, Yilei; Sun, Junlong; Zhan, Cheng; Ni, Wei; Zheng, Yongjun; Wang, Yanqing; Liu, Shenbin
  作者单位：Fudan University; Fudan University; Fudan University; Fudan University; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Fudan University
  摘要：Psychological stress is believed to exacerbate dermatitis, yet the neurobiological mechanisms linking stress to immune processes remain elusive. We identified a subset of prodynorphin-positive (Pdyn+) noradrenergic sympathetic neurons in mice that specifically innervate hairy skin, mediating stress-induced exacerbation of skin inflammation in an eosinophil-dependent manner. Genetic ablation of Pdyn+ sympathetic neurons or eosinophils mitigated stress-evoked worsening of inflammation in atopic ...