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作者:Ibrahim, Tarhan; King, Freddie J.; Toghani, AmirAli; Wang, Luyao; Jenkins, Saskia; Yuen, Enoch Lok Him; Wang, Hung-Yu; Vuolo, Cristina; Eilmann, Nick; Adamkova, Vanda; Chia, Khong-Sam; Castel, Baptiste; Jones, Jonathan D. G.; Carella, Philip; Wu, Chih-Hang; Kourelis, Jiorgos; Kamoun, Sophien; Bozkurt, Tolga O.
作者单位:Imperial College London; University of East Anglia; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); Academia Sinica - Taiwan; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); John Innes Centre
摘要:Upon activation, plant nucleotide-binding leucine-rich repeat (NLR) immune receptors are known to assemble into oligomeric resistosomes that insert into the plasma membrane, forming calcium (Ca2+)-permeable channels and triggering immunity. Here, we found that the RPW8-like coiled-coil NLR (CCR-NLR) N requirement gene 1 (NRG1) primarily targets organelles instead of the plasma membrane. Unlike canonical CC-NLRs, activated NRG1 accumulated at the chloroplast envelope and channeled stromal Ca2+ ...
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作者:Bohm, Robert; Schneider, Alina; Betsch, Cornelia; Lilleholt, Lau
作者单位:University of Vienna; University of Innsbruck; University of Erfurt; Leibniz Association; Bundeswehrkrankenhaus Hamburg; Bernhard Nocht Institut fur Tropenmedizin; University of Copenhagen; University of Copenhagen
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作者:Zhang, Ling; Lang, Yatao; Luo, Zhen; Han, Xinlong; Zeng, Huiying; Li, Chao-Jun
作者单位:Lanzhou University; McGill University
摘要:Indole is widely present in pharmaceuticals and natural products. In this work, we report an intramolecular skeletal editing reaction of tryptamine derivatives enabled by photoreaction of a pendant amide that simultaneously achieves regioselective single-carbon replacement and substitution at the C2 position of indoles. This strategy facilitates deuteration, alkylation, arylation, and acylation at the indole C2 position while also enabling the incorporation of 13C-labeled carbon into the scaff...
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作者:Wang, Cheng; Butts, Carter T.; Hipp, John R.; Lakon, Cynthia M.
作者单位:Wayne State University; University of California System; University of California Irvine; University of California System; University of California Irvine; University of California System; University of California Irvine; University of California System; University of California Irvine
摘要:How far does peer influence spread through social networks before dissipating? This study investigates the diffusion of smoking behavior in adolescent friendship networks using longitudinal data from two schools (n = 3154 students) in the National Longitudinal Study of Adolescent to Adult Health. Using Stochastic Actor-Oriented Models, we simulate interventions targeting heavy smokers using various strategies (random, in-degree, eigenvector centrality) and coverage (10 to 100%). A new exponent...
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作者:Cho, Adrian
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作者:Pennisi, Elizabeth
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作者:Gomez-Marin, Alex
作者单位:Consejo Superior de Investigaciones Cientificas (CSIC); Universidad Miguel Hernandez de Elche; CSIC-UMH - Instituto de Neurociencias de Alicante (IN)
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作者:Jaeckel, Aline
作者单位:University of Wollongong
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作者:Majdzadeh, Reza; Farzanegan, Mohammad Reza
作者单位:University of Essex; Philipps University Marburg
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作者:Garai, Rabindranath; Metcalf, Isaac; Nandi, Nilanjana; Ahlawat, Paramvir; Reyes-Suarez, Braulio; Mandani, Faiz; Zhang, Hao; Kodalle, Tim; Irwin, Michael D.; Katan, Claudine; Sutter-Fella, Carolin M.; Kanatzidis, Mercouri G.; Reddy, G. N. Manjunatha; Even, Jacky; Mohite, Aditya D.
作者单位:Rice University; University of Cambridge; University of Cambridge; Universite de Lille; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Universite de Rennes; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Northwestern University; Northwestern University; Universite de Rennes; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute for Engineering & Systems Sciences (INSIS); Rice University
摘要:Using modeling and structural studies, we show that chloride incorporation in formamidinium lead iodide (FAPI) perovskites alters the energetics of both the formation and degradation pathways. We fabricated films with two coadditives [15 mole % FA chloride (FACl) and 0.5 mole % BA(2)PbI(4), where BA is butylammonium)], in which FACl ensures chloride incorporation and both additives collectively create a compressive lattice strain that stabilizes the FAPI black phase and bypasses the formation ...