2026

最新文章

• Reversible suppression of autophagy in a mouse model reveals neuronal resilience AI翻译
  作者：Eguchi, Tomoya; Abe, Manabu; Tomita, Takuya; Morishita, Hideaki; Saeki, Yasushi; Sakimura, Kenji; Tanaka, Kenji F.; Mizushima, Noboru
  作者单位：University of Tokyo; Niigata University; Niigata University; University of Tokyo; Keio University; University of Tokyo; Kyushu University
  摘要：Impairments in intracellular quality-control mechanisms, including autophagy, affect neuronal integrity and function. Despite numerous studies aimed at slowing neuronal deterioration, it remains unclear whether neuronal function and intracellular quality can be restored once impaired. We developed a mouse model in which autophagy could be rapidly and reversibly regulated to investigate the reversibility of such defects. Suppressing autophagy led to proteome and transcriptome changes, inclusion...
• Recognizing my worth AI翻译
  作者：Fransen, Job
  作者单位：Charles Sturt University
• Diversification of angiosperm reproductive strategies predated the end-Cretaceous extinction AI翻译
  作者：Lee, Jaemin; Contreras, Dori L.; Saulsbury, James G.; Upchurch, Garland R.; Looy, Cindy V.
  作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of Kansas; University of Colorado System; University of Colorado Boulder
  摘要：Angiosperm reproductive evolution is traditionally linked to the end-Cretaceous biotic crisis and subsequent ecological restructuring. Here, we report diverse and unexpectedly large diaspores (dispersal units) from an in situ late Campanian (74.6 million years ago) tropical forest from the Jose Creek Formation in New Mexico. Nearly 80 distinct diaspore morphotypes demonstrate that the flora had increased morphological specialization and an exceptionally large average and range of diaspore volu...
• A bright, sun-splashed future for renewable energy AI翻译
  作者：Wright, Matthew E.
• NIH scientists charged with smuggling viruses into US AI翻译
  作者：Cohen, Jon
• Shifting currents AI翻译
  作者：Voosen, Paul
• Spontaneous problem-solving in bumble bees AI翻译
  作者：Bhambore, Akshaye A.; Akmese, Ece N.; Hakkinen, Emma; Jussila, Milla K.; Kantola, Juha-Heikki; Loukola, Olli J.
  作者单位：University of Oulu; University of Oulu
  摘要：Problem-solving using novel solutions without explicit training is often considered a hallmark of cognitive flexibility. We investigated whether bumble bees (Bombus terrestris) could solve a novel object manipulation task spontaneously. Bees trained to associate a blue ring (flower) on the floor with a reward successfully moved a ball underneath a flower relocated to the ceiling to reach the flower. In control experiments in which the flower was out of sight when ball movement began and remain...
• Believing I belong AI翻译
  作者：Ghai, Sakshi
  作者单位：University of London; London School Economics & Political Science
• Unexpected expansion and regrowth in Earth's mangrove forests over the past four decades AI翻译
  作者：Zhang, Zhen; Murray, Nicholas J.; Song, Xiao-Peng; Bunting, Pete; Worthington, Thomas A.; Fatoyinbo, Lola; Mao, Dehua; Jia, Mingming; Arifanti, Virni Budi; Aung, Toh; San Htay, San; Friess, Daniel A.
  作者单位：Tulane University; James Cook University; University System of Maryland; University of Maryland College Park; Aberystwyth University; University of Cambridge; Massachusetts Institute of Technology (MIT); National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Chinese Academy of Sciences; Northeast Institute of Geography & Agroecology, CAS; National Research & Innovation Agency of Indonesia (BRIN)
  摘要：Global mangrove forests have disappeared rapidly because of deforestation but have also regrown through natural regeneration and restoration. Yet their long-term trends in extent and canopy cover remain poorly quantified. By developing a global dataset of annual mangrove extent and canopy cover, we show that losses (long-term conversion) and degradation (canopy thinning) have both reduced since the 1980s and have been largely offset by regeneration and seaward expansion in the past decade. Con...
• Reward magnitude determines reinforcement learning efficiency AI翻译
  作者：Gong, Sheng; Martell, Alyssa; Dudman, Joshua T.; Coddington, Luke T.
  作者单位：Howard Hughes Medical Institute
  摘要：INTRODUCTION Across different disciplines that share an interest in learning, from artifical intelligence (AI) to experimental psychology, it has long been assumed that there is a free parameter, the learning rate, that determines individual variance in learning efficiency and is relatively independent of the magnitude of reward. This suggests that learning depends primarily on the amount of experience (number of rewards). However, recent theoretical work mapping dopamine (DA) function onto re...