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作者：Chakrabarti, Arhit; Ni, Yang; Pati, Debdeep; Mallick, Bani K.
作者单位：Texas A&M University System; Texas A&M University College Station; University of Wisconsin System; University of Wisconsin Madison
摘要：We consider the problem of clustering grouped data for which the observations may include group-specific variables in addition to the variables that are shared across groups. This type of data is common in cancer genomics where the molecular information is usually accompanied by cancer-specific clinical information. Existing grouped clustering methods only consider the shared variables, thereby ignoring valuable information from the cancer-specific variables. To allow for these cancer-specific...
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作者：Choi, Junsouk; Chapkin, Robert S.; Ni, Yang
作者单位：Korea University; Texas A&M University System; Texas A&M University College Station; University of Texas System; University of Texas Austin
摘要：Observational zero-inflated count data arise in a wide range of areas such as genomics. One of the common research questions is to identify causal relationships by learning the structure of a sparse directed acyclic graph (DAG). While structure learning of DAGs has been an active research area, existing methods do not adequately account for excessive zeros and, therefore, are not suitable for modeling zero-inflated count data. Moreover, it is often interesting to study differences in the causa...
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作者：Hu, Wei; Huang, Danyang; Zhang, Bo
作者单位：Chinese Academy of Sciences; Renmin University of China
摘要：Social network platforms today generate vast amounts of data, including network structures and a large number of user-defined tags, which reflect users' interests. The dimensionality of these personalized tags can be ultrahigh, posing challenges for model analysis in targeted preference analysis. Traditional categorical feature screening methods overlook the network structure, which can lead to incorrect feature set and suboptimal prediction accuracy. This study focuses on feature screening fo...
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作者：Liu, Xiao; Hu, Feifang; Ma, Wei
作者单位：Renmin University of China; George Washington University
摘要：In clinical trials, covariate-adaptive randomization (CAR) procedures are used to balance important covariates for more convincing results and enhanced statistical efficiency. Although most CAR procedures focus on trials with 1:1 allocation ratio, the demand for unequal allocation is growing. Therefore, this paper proposes a CAR framework that unifies numerous existing procedures and can balance general (discrete, continuous, or their combinations) covariates under any allocation ratio. To eva...
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作者：Jiang, Lei; Peng, Liang; Qin, Hongling; Yang, Bingduo
作者单位：University System of Ohio; Kent State University; Kent State University Kent; Kent State University Salem; University System of Georgia; Georgia State University; Auburn University System; Auburn University; Guangdong University of Finance & Economics
摘要：The predictability test is critical in developing momentum trading strategies. In time-series momentum (TSM) tests via linear predictive regressions, the classical and Newey-West t-tests have size distortions because of endogeneity and a lack of enough finite moments. To tackle these issues, this paper proposes a new test that features a model of the error correlations, weighted least squares estimation, and the random weighted bootstrap method. Simulations confirm its accurate size and good p...
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作者：Maier, Eva-Maria; Stoecker, Almond; Fitzenberger, Bernd; Greven, Sonja
作者单位：Humboldt University of Berlin; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; University of Erlangen Nuremberg; University of Erlangen Nuremberg
摘要：Motivated by research on gender identity norms and the distribution of the woman's share in a couple's total labor income, we consider additive regression models for densities as responses with scalar covariates. To preserve nonnegativity and integration to one under vector space operations, we formulate the model for densities in a Bayes Hilbert space, which allows to not only consider continuous densities but also, for example, discrete or mixed densities. Mixed ones occur in our application...
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作者：McKennan, Chris; Sang, Zhe; Shi, Yi
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Icahn School of Medicine at Mount Sinai
摘要：Nanobodies are small antibody fragments derived from camelids that selectively bind to antigens. These proteins have marked physicochemical properties that support advanced therapeutics, including possible treatments for SARS-CoV-2. To realize their potential, bottom-up proteomics via liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been proposed to identify antigen-specific nanobodies at the proteome scale, where a critical component of this pipeline is matching nanobody peptides...
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作者：Seymour, Rowland; Nyarko-Agyei, Albert; McCabe, Helen; Severn, Katie; Sirl, David; Kypraios, Theodore; Taylor, Adam
作者单位：University of Birmingham; University of Nottingham; University of Nottingham; University of Nottingham
摘要：Forcing someone into marriage against their will is a violation of their human rights. In 2021, the county of Nottinghamshire, U.K., launched a strategy to tackle forced marriage and violence against women and girls. We set out to map the risk of forced marriage across the county to support the strategy and enable the development of local interventions. However, there was no centralised database for forced marriage in the county and carrying out a survey using standard survey methods was unlik...
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作者：Diaz-Rodriguez, Jairo; Gomez, Juan Pablo; Orange, Jeremy P.; Burkett-Cadena, Nathan D.; Wisely, Samantha M.; Blackburn, Jason K.; Sardy, Sylvain
作者单位：York University - Canada; Universidad del Norte Colombia; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; University of Geneva
摘要：Identifying areas in a landscape where individuals have a higher likelihood of disease infection is key to managing diseases. Unlike conventional methods relying on ecological assumptions, we perform a novel epidemiological tomography for the estimation of landscape propensity to disease infection, using GPS animal tracks in a manner analogous to tomographic techniques in positron emission tomography (PET). Treating tracking data as random Radon transforms, we analyze Cervid movements in a gam...
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作者：Lee, I-Chen; Chen, Ray-Bing; Wong, Weng Kee
作者单位：National Cheng Kung University; National Tsing Hua University; University of California System; University of California Los Angeles
摘要：Polymer composite materials are widely used in industries, such as transportation and renewable energy, due to their lightweight nature, high strength, and outstanding durability. Ensuring their long-term reliability under fatigue conditions is critical for safety and performance, and this requires efficient accelerated life testing (ALT) methods. The ALT aims to provide precise lifetime predictions while minimizing costs. However, existing approaches often rely on locally optimal designs depe...
