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作者:Zin, Isaac; China, Arnab; Khan, Krishnendu; Nag, Jeetendra K.; Vasu, Kommireddy; Deshpande, Gauravi M.; Ghosh, Prabar K.; Khan, Debjit; Ramachandiran, Iyappan; Ganguly, Shinjini; Tamagno, Ilaria; Willard, Belinda; Gogonea, Valentin; Fox, Paul L.
作者单位:Cleveland Clinic Foundation; University System of Ohio; Cleveland State University; Cleveland Clinic Foundation; Gandhi Institute of Technology & Management (GITAM); Cleveland Clinic Foundation; Cleveland Clinic Foundation
摘要:Glutamyl- prolyl-tRNA synthetase (EPRS1) is a bifunctional aminoacyl-tRNA- synthetase (aaRS) essential for decoding the genetic code. EPRS1 resides, with seven other aaRSs and three noncatalytic proteins, in the cytoplasmic multi-tRNA synthetase complex (MSC). Multiple MSC- resident aaRSs, including EPRS1, exhibit stimulus- dependent release from the MSC to perform noncanonical activities distinct from their primary function in protein synthesis. Here, we show EPRS1 is present in both cytoplas...
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作者:An, Minde; Prinn, Ronald G.; Western, Luke M.; Yao, Bo; Zhao, Xingchen; Kim, Jooil; Muehle, Jens; Chi, Wenxue; Harth, Christina M.; Hu, Jianxin; Ganesan, Anita L.; Rigby, Matthew
作者单位:Massachusetts Institute of Technology (MIT); Peking University; University of Bristol; Fudan University; Fudan University; China Meteorological Administration; Meteorological Observation Center, China Meteorological Administration; University of California System; University of California San Diego; Scripps Institution of Oceanography; University of Bristol
摘要:The perfluorocarbons tetrafluoromethane (CF4, PFC-14) and hexafluoroethane (C2F6, PFC-116) are potent greenhouse gases with near-permanent atmospheric lifetimes relative to human timescales and global warming potentials thousands of times that of CO2. Using long-term atmospheric observations from a Chinese network and an inverse modeling approach (top-down method), we determined that CF4 emissions in China increased from 4.7 (4.2-5.0, 68% uncertainty interval) Gg y(-1) in 2012 to 8.3 (7.7-8.9)...
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作者:Jegla, Timothy; Simonson, Benjamin T.; Spafford, J. David
作者单位:Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University of Waterloo
摘要:The Shaker family of voltage- gated K+ channels has been thought of as an animal- specific ion channel family that diversified in concert with nervous systems. It comprises four functionally independent gene subfamilies (Kv1-4) that encode diverse neuronal K+ currents. Comparison of animal genomes predicts that only the Kv1 subfamily was present in the animal common ancestor. Here, we show that some choanoflagellates, the closest protozoan sister lineage to animals, also have Shaker family K+ ...
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作者:Jiang, Jilian; Zou, Xinyu; Mitchell, Ross N.; Zhang, Yigang; Zhao, Yong; Yin, Qing - Zhu; Yang, Wei; Zhou, Xiqiang; Wang, Hao; Spencer, Christopher J.; Shan, Xiaocai; Wu, Shitou; Li, Guangming; Qin, Kezhang; Li, Xian - Hua
作者单位:Chinese Academy of Sciences; Institute of Geology & Geophysics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Institute of Geology & Geophysics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Institute of Geology & Geophysics, CAS; Macau University of Science & Technology; University of California System; University of California Davis; Chinese Academy of Sciences; Institute of Geology & Geophysics, CAS; Queens University - Canada
摘要:Due to the scarcity of rock samples, the Hadean Era predating 4 billion years ago (Ga) poses challenges in understanding geological processes like subaerial weathering and plate tectonics that are critical for the evolution of life. The Jack Hills zircon from Western Australia, the primary Hadean samples available, offer valuable insights into magma sources and tectonic genesis through trace element signatures. However, a consensus on these signatures has not been reached. To address this, we ...
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作者:Nelson, Randy J.; DeVries, A. Courtney; Prendergast, Brian J.
作者单位:West Virginia University; West Virginia University; University of Chicago
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作者:Wang, Guocheng; Su, Qi; Wang, Long; Plotkin, Joshua B.
作者单位:Peking University; University of Pennsylvania; Shanghai Jiao Tong University; Peking University; University of Pennsylvania
摘要:Humans update their social behavior in response to past experiences and changing environments. Behavioral decisions are further complicated by uncertainty in the outcome of social interactions. Faced with uncertainty, some individuals exhibit risk aversion while others seek risk. Attitudes toward risk may depend on socioeconomic status; and individuals may update their risk preferences over time, which will feedback on their social behavior. Here, we study how uncertainty and risk preferences ...
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作者:Zwebner, Yonat; Miller, Moses; Grobgeld, Noa; Goldenberg, Jacob; Mayo, Ruth
作者单位:Reichman University; Reichman University; Hebrew University of Jerusalem; Columbia University; Hebrew University of Jerusalem
摘要:Our given name is a social tag associated with us early in life. This study investigates the possibility of a self-fulfilling prophecy effect wherein individuals' facial appearance develops over time to resemble the social stereotypes associated with given names. Leveraging the face-name matching effect, which demonstrates an ability to match adults' names to their faces, we hypothesized that individuals would resemble their social stereotype (name) in adulthood but not in childhood. To test t...
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作者:Fiorella, Kathryn J.; Bageant, Elizabeth R.; Thilsted, Shakuntala H.; Heilpern, Sebastian A.
作者单位:Cornell University; Cornell University
摘要:The global biodiversity that underpins wild food systems-including fisheries-is rapidly declining. Yet, we often have only a limited understanding of how households use and benefit from biodiversity in the ecosystems surrounding them. Explicating these relationships is critical to forestall and mitigate the effects of biodiversity declines on food and nutrition security. Here, we quantify how biodiversity filters from ecosystems to household harvest, consumption, and sale, and how ecological t...
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作者:Kianishahvandi, Mostafa Kiani; Adhikari, Surendra; Dumberry, Mathieu; Mishra, Siddhartha; Soja, Benedikt
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich; California Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); University of Alberta; Swiss Federal Institutes of Technology Domain; ETH Zurich
摘要:The melting of ice sheets and global glaciers results in sea-level rise, a pole-to-equator mass transport increasing Earth's oblateness and resulting in an increase in the length of day (LOD). Here, we use observations and reconstructions of mass variations at the Earth's surface since 1900 to show that the climate-induced LOD trend hovered between 0.3 and 1.0 ms/cy in the 20th century, but has accelerated to 1.33 +/- 0.03 ms/cy since 2000. We further show that surface mass transport fully exp...
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作者:Petrone, Mary E.; Grove, Joe; Melade, Julien; Mifsud, Jonathon C. O.; Parry, Rhys H.; Marzinelli, Ezequiel M.; Holmes, Edward C.
作者单位:University of Sydney; University of Glasgow; University of Queensland; University of Sydney
摘要:It is commonly held that there is a fundamental relationship between genome size and error rate, manifest as a notional error threshold that sets an upper limit on genome sizes. The genome sizes of RNA viruses, which have intrinsically high mutation rates due to a lack of mechanisms for error correction, must therefore be small to avoid accumulating an excessive number of deleterious mutations that will ultimately lead to population extinction. The proposed exceptions to this evolutionary rule...