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作者:Karatas, Mustafa; Cutright, Keisha M.
作者单位:Nazarbayev University; Duke University
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作者:Pecheva, Diliana; Smith, Diana M.; Casey, B. J.; Woodward, Lianne J.; Dale, Anders M.; Filippi, Christopher G.; Watts, Richard
作者单位:University of California System; University of California San Diego; University of California System; University of California San Diego; Columbia University; University of Canterbury; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of Toronto; Hospital for Sick Children (SickKids); University of Toronto; Hospital for Sick Children (SickKids)
摘要:Some mental health problems such as depression and anxiety are more common in females, while others such as autism and attention deficit/hyperactivity (AD/H) are more common in males. However, the neurobiological origins of these sex differences are poorly understood. Animal studies have shown substantial sex differences in neuronal and glial cell structure, while human brain imaging studies have shown only small differences, which largely reflect overall body and brain size. Advanced diffusio...
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作者:Cheng, Chen; Xing, Zhiyao; Zhang, Wenxin; Zheng, Lei; Zhao, Hongting; Zhang, Xiao; Ding, Yibing; Qiao, Tong; Li, Yi; Meyron-Holtz, Esther G.; Missirlis, Fanis; Fan, Zhiwen; Li, Kuanyu
作者单位:Nanjing University; Nanjing University; Nanjing University; Technion Israel Institute of Technology; CINVESTAV - Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional; Nanjing University
摘要:Colorectal cancer and Crohn's disease patients develop pyogenic liver abscesses due to failures of immune cells to fight off bacterial infections. Here, we show that mice lacking when the intestinal tissue was injured with dextran sodium sulfate treatment. Further studies demonstrated that Irp2 is required for lysosomal acidification and biogenesis, both of which are crucial for bacterial clearance. In Irp2- deficient liver tissue or macrophages, the nuclear location of transcription factor EB...
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作者:Moore, Don A.; Schroeder, Juliana; Bailey, Erica R.; Gershon, Rachel; Moore, Joshua E.; Simmons, Joseph P.
作者单位:University of California System; University of California Berkeley; Carleton College; University of Pennsylvania
摘要:There are some limitations to our approach. First, we attempted to replicate only the five online experiments, not the three additional experiments. Further, we cannot identify why the published effects may not have replicated; our close adherence to the authors' original procedures means that any potential moderators are well hidden. Does thinking about God increase reliance on AI in decisionmaking? The results of our replications suggest that the evidence is less compelling than the original...
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作者:Xia, Tao; Chen, Danni; Zeng, Shengzi; Yao, Ziqing; Liu, Jing; Qin, Shaozheng; Paller, Ken A.; Platas, S. Gabriela Torres; Antony, James W.; Hu, Xiaoqing
作者单位:University of Hong Kong; Harvard University; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Harvard University; Harvard Medical School; Hong Kong Polytechnic University; Beijing Normal University; Beijing Normal University; Northwestern University; California State University System; California Polytechnic State University San Luis Obispo; The University of Hong Kong Shenzhen Institute of Research & Innovation; University of Hong Kong
摘要:Recollecting painful or traumatic experiences can be deeply troubling. Sleep may offer an opportunity to reduce such suffering. We developed a procedure to weaken older aversive memories by reactivating newer positive memories during sleep. Participants viewed 48 nonsense words each paired with a unique aversive image, followed by an overnight sleep. In the next evening, participants learned associations between half of the words and additional positive images, creating interference. During th...
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作者:Che, Shun; Guan, Xun; Rodrigues, Roselyn; Yu, Yaochun; Xie, Yongchao; Liu, Chong; Men, Yujie
作者单位:University of California System; University of California Riverside; University of Illinois System; University of Illinois Urbana-Champaign; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Stanford University; Gonzaga University; Swiss Federal Institutes of Technology Domain; Swiss Federal Institute of Aquatic Science & Technology (EAWAG)
摘要:Per- and polyfluoroalkyl substances (PFAS), particularly the perfluorinated ones, are recalcitrant to biodegradation. By integrating an enrichment culture of reductive defluorination with biocompatible electrodes for the electrochemical process, a deeper defluorination of a C6- perfluorinated unsaturated PFAS was achieved compared to the biological or electrochemical system alone. Two synergies in the bioelectrochemical system were identified: i) The in- series microbial- electrochemical deflu...
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作者:Davies, Liam Courtney-; Fiorentini, Marco; Dalstra, Hilke; Hagemann, Steffen; Ramanaidou, Erick; Danisik, Martin; Evans, Noreen J.; Rankenburg, Kai; Mcinnes, Brent I. A.
作者单位:Curtin University; University of Western Australia; Rio Tinto; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Mineral Resources
摘要:Banded iron formations (BIFs) archive the relationship between Earth's lithosphere, hydrosphere, and atmosphere through time. However, constraints on the origin of Earth's largest ore deposits, hosted by BIFs, are limited by the absence of direct geochronology. Without this temporal context, genetic models cannot be correlated with tectono-thermal and atmospheric drivers responsible for BIF upgrading through time. Utilizing in situ iron oxide U-Pb geochronology, we provide a direct timeline of...
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作者:Delecroix, Clara; van Nes, Egbert H.; Scheffer, Marten; van de Leemput, Ingrid A.
作者单位:Wageningen University & Research
摘要:The possibility to anticipate critical transitions through detecting loss of resilience has attracted attention in many fields. Resilience indicators rely on the mathematical concept of critical slowing down, which means that a system recovers more slowly from external perturbations when it gets closer to tipping point. This decrease in recovery rate can be reflected in rising autocorrelation and variance in data. To test whether resilience is changing, resilience indicators are often calculat...
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作者:Singh, Abhishek; Chakraborty, Janardan; Pal, Sumit; Das, Dibyendu
作者单位:Indian Institute of Science Education & Research (IISER) - Kolkata; Indian Institute of Science Education & Research (IISER) - Kolkata
摘要:The evolution of complex chemical inventory from Darwin's nutrient- rich warm pond necessitated rudimentary yet efficient catalytic folds. Short peptides and their self- organized microstructures, ranging from spherical colloids to amyloidogenic aggregates might have played a crucial role in the emergence of contemporary catalytic entities. However, the question of how short peptide fragments had functions akin to contemporary complex enzymes to catalyze cleavage and formation of highly stable...
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作者:Farahvash, Ardavan; Willard, Adam P.
作者单位:Massachusetts Institute of Technology (MIT)
摘要:In this manuscript, we provide a general theory for how surface phonons couple to molecular adsorbates. Our theory maps the extended dynamics of a surface's atomic vibrational motions to a generalized Langevin equation, and by doing so captures these dynamics in a single quantity: the non-Markovian friction. The different frequency components of this friction are the phonon modes of the surface slab weighted by their coupling to the adsorbate degrees of freedom. Using this formalism, we demons...