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作者:Bierman, Paul R.; Mastro, Halley M.; Peteet, Dorothy M.; Corbett, Lee B.; Steig, Eric J.; Halsted, Chris T.; Caffee, Marc M.; Hidy, Alan J.; Balco, Greg; Bennike, Ole; Rock, Barry
作者单位:University of Vermont; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Goddard Institute for Space Studies; Columbia University; University of Washington; University of Washington Seattle; Williams College; Purdue University System; Purdue University; United States Department of Energy (DOE); Lawrence Livermore National Laboratory; Geological Survey Of Denmark & Greenland; University System Of New Hampshire; University of New Hampshire
摘要:The persistence and size of the Greenland Ice Sheet (GrIS) through the Pleistocene is uncertain. This is important because reconstructing changes in the GrIS determines its contribution to sea level rise during prior warm climate periods and informs future projections. To understand better the history of Greenland's ice, we analyzed glacial till collected in 1993 from below 3 km of ice at Summit, Greenland. The till contains plant fragments, wood, insect parts, fungi, and cosmogenic nuclides s...
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作者:Deguenther, Julius; van der Meer, Jann; Seifert, Udo
作者单位:University of Stuttgart
摘要:The laws of thermodynamics apply to biophysical systems on the nanoscale as described by the framework of stochastic thermodynamics. This theory provides universal, exact relations for quantities like work, which have been verified in experiments where a fully resolved description allows direct access to such quantities. Complementary studies consider partially hidden, coarse-grained descriptions, in which the mean entropy production typically is not directly accessible but can be bounded in t...
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作者:Frank, Mor; Ni, Pengyu; Jensen, Matthew; Gerstein, Mark B.
作者单位:Yale University; Yale University; Yale University; Yale University
摘要:Protein phase transitions (PPTs) from the soluble state to a dense liquid phase (forming droplets via liquid-liquid phase separation) or to solid aggregates (such as amyloids) play key roles in pathological processes associated with age-related diseases such as Alzheimer's disease. Several computational frameworks are capable of separately predicting the formation of droplets or amyloid aggregates based on protein sequences, yet none have tackled the prediction of both within a unified framewo...
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作者:Furumo, Paul R.; Yu, Jevan; Hogan, J. Aaron; de Carvalho, Luis M. Tavares; Brito, Brenda; Lambin, Eric F.
作者单位:Stanford University; Stanford University; Massachusetts Institute of Technology (MIT); United States Department of Agriculture (USDA); United States Forest Service; Universidade Federal de Lavras
摘要:Satellite- based land use monitoring and farm- level traceability offer opportunities for targeted zero- deforestation interventions on private lands. Brazil's Rural Environmental Registry (Cadastro Ambiental Rural, or CAR), a land cadaster based on self- declaration of property boundaries, was created to monitor compliance with national forest laws. It has become an important enabling measure for sustainable supply chain initiatives like the Amazon Soy Moratorium. However, CAR enrollment is i...
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作者:Lou, Chenjie; Liu, Jie; Sun, Xuan; Zhang, Wenda; Xu, Ligang; Luo, Huajie; Chen, Yongjin; Gao, Xiang; Kuang, Xiaojun; Fu, Jipeng; Xu, Jun; Su, Lei; Ma, Jiwei; Tang, Mingxue
作者单位:China Jiliang University; Guilin University of Technology; University of Science & Technology Beijing; Nankai University; Nankai University; Tongji University
摘要:Na5YSi4O12 (NYSO) is demonstrated as a promising electrolyte with high ionic conductivity and low activation energy for practical use in solid Na-ion batteries. Solid- state NMR was employed to identify the six types of coordination of Na+ ions and migration pathway, which is vital to master working mechanism and enhance performance. The assignment of each sodium site is clearly determined from high- quality 23 Na NMR spectra by the aid of Density Functional Theory calculation. Well- resolved ...
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作者:Martinez-Ortiz, L.; Pupo-Santos, R.; Altshuler, P.; Altshuler, E.
作者单位:Universidad de la Habana
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作者:Park, Jeonghwan; Lee, Kangmin; Lee, Jungtaek; Kim, Dawon; Lee, Myounghyun; Seo, Kwanyong
作者单位:Ulsan National Institute of Science & Technology (UNIST); Ulsan National Institute of Science & Technology (UNIST)
摘要:Transparent solar cells (TSCs) hold substantial potential as continuous energy generators, enabling their use in situations where conventional devices may not be feasible. However, research aimed at modularizing TSCs for the purpose of regulating the overall voltage and current they produce, a critical step toward practical application, is still in its nascent stages. In this study, we explored a custom- designed, all- back- contact (ABC) configuration, which situates all electrical contacts o...
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作者:Ravindran, Sandeep
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作者:Shan, Liying; Wang, Wenmeng; Du, Lijuan; Li, Dangdang; Wang, Yunxuan; Xie, Yuyan; Li, Hongyan; Wang, Jiale; Shi, Zhihao; Zhou, Yang; Zhu, Daling; Sui, Guangchao; Liu, Fang
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作者:Zhang, Yi; Lou, Jiacheng; Liu, Yabin; Jin, Peng; Tan, Yun; Song, Huan; Jin, Wen; Wang, Dan; Dong, Fangyi; Wu, Shishuang; Fang, Hai; Chen, Saijuan; Chen, Zhu; Wang, Kankan
作者单位:Shanghai Jiao Tong University; Chinese Academy of Sciences; Dalian Medical University; Shanghai Jiao Tong University
摘要:In acute promyelocytic leukemia (APL), the promyelocytic leukemia- retinoic acid receptor alpha (PML/RAR alpha) fusion protein destroys PML nuclear bodies (NBs), leading to the formation of microspeckles. However, our understanding, largely learned from morphological observations, lacks insight into the mechanisms behind PML/RAR alpha- mediated microspeckle formation and its role in APL leukemogenesis. This study presents evidence uncovering liquid-liquid phase separation (LLPS) as a key mecha...