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作者:Das, Amiya Prakash; Zhao, Jidong; Sweijen, Thomas
作者单位:Hong Kong University of Science & Technology; Utrecht University
摘要:This paper presents pore unit assembly-discrete element model (PUA-DEM), a pore-scale hydromechanical framework that resolves interactions between mobile granular particles and multiphase fluids in unsaturated granular media. The framework uniquely integrates DEM with pore-scale hydrodynamic models to capture unsaturated flow dynamics, while leveraging a two-way coupling mechanism to ensure bidirectional fluid-grain feedback through stabilized domain partitioning. Further innovations include a...
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作者:Reich, Peter B.; Grace, Kathryn; Agrawal, Arun; Nagendra, Harini
作者单位:University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Minnesota System; University of Minnesota Twin Cities; University of Minnesota System; University of Minnesota Twin Cities; University of Notre Dame; Azim Premji Foundation; Azim Premji University Bengaluru
摘要:Mitigating climate change and social injustice are critical, interwoven challenges. Climate change is driven by grossly unequal contributions to elevated greenhouse gas emissions among individuals, socioeconomic groups, and nations. Yet, its deleterious impacts disproportionately affect poor and less powerful nations, and the poor and the less powerful within each nation. This climate injustice prompts a call for mitigation strategies that buffer the poorest and the most vulnerable against cli...
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作者:Petroff, Zachary J.; Jayaraman, Swapnaa; Smith, Linda B.; Candy, T. Rowan; Bonnen, Kathryn
作者单位:Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington
摘要:The structure of the environment includes more horizontal and vertical (i.e. cardinal) orientations than oblique orientations, meaning that edges tend to be aligned with or perpendicular to the direction of gravity. This bias in the visual scene is associated with a bias in visual sensitivity in adults. Although infants must learn to function in this biased environment, their immature motor control prevents them from consistently orienting themselves, relative to gravity. This study therefore ...
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作者:Daicho, Kazuho; Fujisawa, Shuji; Doi, Yoshinori; Suzuki, Michio; Shiomi, Junichiro; Saito, Tsuguyuki
作者单位:University of Tokyo; University of Tokyo
摘要:Plant cell walls are composed of skeletal cellulose and a filling matrix of hemicelluloses and lignin. Cellulose has slender crystallite units referred to as microfibrils or elementary fibrils, and these crystallites form a dense network skeleton in the cell walls. In this study, we assessed the morphology and crystallinity of individually dispersed microfibrils isolated from the cell walls of wood, cotton, and ramie celluloses. It is well known that microfibrils in higher plants exhibit struc...
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作者:Johnson, Nicole A.; Dickenson, Jessica A.; MacKenzie, Benjamin W. L.; Isakovich, Rodion; Kalker, Anne; Bouten, Janne; Strzalkowski, Nicholas D. J.; Harman, Taylor S.; Holmstrom, Pontus; Kunwar, Ajaya J.; Thakur, Nilam; Dhungel, Sunil; Sherpa, Nima; Bigham, Abigail W.; Brutsaert, Tom; Day, Trevor A.
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作者:Jenewein, Christian; Maiz-Sicilia, Aurora; Rull, Fernando; Gonzalez-Souto, Lorena; Garcia-Ruiz, Juan Manuel
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作者:Karayel, Ozge; Soung, Allison; Gurung, Hem; Schubert, Alexander F.; Klaeger, Susan; Kschonsak, Marc; Al-Maraghi, Aljazi; Bhat, Ajaz A.; Akil, Ammira S. Alshabeeb; Dugger, Debra L.; Webster, Joshua D.; French, Dorothy M.; Anand, Dhullipala; Soni, Naharmal; Fakhro, Khalid A.; Rose, Christopher M.; Harris, Seth F.; Ndoja, Ada; Newton, Kim; Dixit, Vishva M.
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作者:Hou, Jinchao; Magliozzi, Roberta; Chen, Yun; Wu, Junjie; Wulf, John; Strout, Gregory; Fang, Xiangming; Colonna, Marco
作者单位:Zhejiang University; Washington University (WUSTL); Imperial College London; Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Zhejiang University
摘要:We investigated the role of Triggering Receptor Expressed on Myeloid cells 2 (TREM2) in myelin regeneration in the brain. TREM2 is a receptor that activates microglia, which are crucial for clearing myelin debris and promoting remyelination. Previous studies in a mouse model of demyelination induced by the copper-chelating agent Cuprizone (CPZ) have shown that stimulation of TREM2 with a monoclonal antibody reduces demyelination, while deleting the Trem2 gene in mice impairs remyelination. Her...
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作者:Leung, Eugina; Urminsky, Oleg
作者单位:Tulane University; University of Chicago
摘要:Information search platforms, from Google to AI-assisted search engines, have transformed information access but may fail to promote a shared factual foundation. We demonstrate that the combination of users' prior beliefs influencing their search terms and the narrow scope of search algorithms can limit belief updating from search. We test this narrow search effect across 21 studies (14 preregistered) using various topics (e.g., health, financial, societal, political) and platforms (e.g., Goog...
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作者:Kumar, Abhishek; Senechal, David; Tremblay, A. M. S.