作者:Winding, Michael; Pedigo, Benjamin D.; Barnes, Christopher L.; Patsolic, Heather G.; Park, Youngser; Kazimiers, Tom; Fushiki, Akira; Andrade, Ingrid V.; Khandelwal, Avinash; Valdes-Aleman, Javier; Li, Feng; Randel, Nadine; Barsotti, Elizabeth; Correia, Ana; Fetter, Richard D.; Hartenstein, Volker; Priebe, Carey E.; Vogelstein, Joshua T.; Cardona, Albert; Zlatic, Marta
作者单位:University of Cambridge; MRC Laboratory Molecular Biology; Howard Hughes Medical Institute; Johns Hopkins University; University of Cambridge; Johns Hopkins University; Johns Hopkins University; Columbia University; University of California System; University of California Los Angeles; Stanford University
摘要:Brains contain networks of interconnected neurons and so knowing the network architecture is essential for understanding brain function. We therefore mapped the synaptic-resolution connectome of an entire insect brain (Drosophila larva) with rich behavior, including learning, value computation, and action selection, comprising 3016 neurons and 548,000 synapses. We characterized neuron types, hubs, feedforward and feedback pathways, as well as cross-hemisphere and brain-nerve cord interactions....
作者:Chittka, Lars; Rossi, Natacha
作者单位:University of London; Queen Mary University London; University of Sussex
作者:Wilsdon, James
作者单位:University of London; University College London
作者:Wolff, Jan O.; Scheiderer, Lukas; Engelhardt, Tobias; Engelhardt, Johann; Matthias, Jessica; Hell, Stefan W.
作者单位:Max Planck Society
摘要:We introduce an interferometric MINFLUX microscope that records protein movements with up to 1.7 nanometer per millisecond spatiotemporal precision. Such precision has previously required attaching disproportionately large beads to the protein, but MINFLUX requires the detection of only about 20 photons from an approximately 1-nanometer-sized fluorophore. Therefore, we were able to study the stepping of the motor protein kinesin-1 on microtubules at up to physiological adenosine-5 ' triphospha...
作者:Fei, Jinyu; Zhou, Ruobo
作者单位:Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park
作者:Jiang, Song; Neuman, Tomas; Boeglin, Alex; Scheurer, Fabrice; Schull, Guillaume
作者单位:Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Physics (INP); Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS)
摘要:Intrinsic optoelectronic properties of atomically precise graphene nanoribbons (GNRs) remain largely unexplored because of luminescence quenching effects that are due to the metallic substrate on which the ribbons are grown. We probed excitonic emission from GNRs synthesized on a metal surface with atomic-scale spatial resolution. A scanning tunneling microscope (STM)-based method to transfer the GNRs to a partially insulating surface was used to prevent luminescence quenching of the ribbons. ...
作者:Warren, Cody J.; Sawyer, Sara L.
作者单位:University System of Ohio; Ohio State University; University of Colorado System; University of Colorado Boulder