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作者:Matarese, Giuseppe
作者单位:University of Naples Federico II; Consiglio Nazionale delle Ricerche (CNR); Istituto per Endocrinologia e Oncologia Gaetano Salvatore (IEOS-CNR)
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作者:Metz, Eva-Marie; Vardag, Sanam N.; Basu, Sourish; Jung, Martin; Ahrens, Bernhard; El-Madany, Tarek; Sitch, Stephen; Arora, Vivek K.; Briggs, Peter R.; Friedlingstein, Pierre; Goll, Daniel S.; Jain, Atul K.; Kato, Etsushi; Lombardozzi, Danica; Nabel, Julia E. M. S.; Poulter, Benjamin; Seferian, Roland; Tian, Hanqin; Wiltshire, Andrew; Yuan, Wenping; Yue, Xu; Zaehle, Soenke; Deutscher, Nicholas M.; Griffith, David W. T.; Butz, Andre
作者单位:Ruprecht Karls University Heidelberg; Ruprecht Karls University Heidelberg; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; University System of Maryland; University of Maryland College Park; Max Planck Society; University of Exeter; Environment & Climate Change Canada; Canadian Centre for Climate Modelling & Analysis (CCCma); Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Oceans & Atmosphere; University of Exeter; Institut Polytechnique de Paris; Ecole Polytechnique; Universite Paris Saclay; Universite PSL; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Earth Sciences & Astronomy (INSU); Sorbonne Universite; Universite Paris Saclay; Universite Paris Cite; CEA; Centre National de la Recherche Scientifique (CNRS); University of Illinois System; University of Illinois Urbana-Champaign; National Center Atmospheric Research (NCAR) - USA; Max Planck Society; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Centre National de la Recherche Scientifique (CNRS); Universite de Toulouse; Boston College; Met Office - UK; Hadley Centre; Southern Marine Science & Engineering Guangdong Laboratory; Southern Marine Science & Engineering Guangdong Laboratory (Zhuhai); Sun Yat Sen University; Nanjing University of Information Science & Technology; University of Wollongong; Ruprecht Karls University Heidelberg
摘要:The Australian continent contributes substantially to the year-to-year variability of the global terrestrial carbon dioxide (CO2) sink. However, the scarcity of in situ observations in remote areas prevents the deciphering of processes that force the CO2 flux variability. In this study, by examining atmospheric CO2 measurements from satellites in the period 2009-2018, we find recurrent end-of-dry-season CO2 pulses over the Australian continent. These pulses largely control the year-to-year var...
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作者:Curry, Andrew
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作者:del Valle, Andrea
作者单位:Karolinska Institutet
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作者:Normile, Dennis
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作者:Schraml, Barbara U.
作者单位:University of Munich; University of Munich
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作者:Curry, Andrew
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作者:Brainard, Jeffrey
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作者:Mukadam, Aamir S.; Miller, Lauren V. C.; Smith, Annabel E.; Vaysburd, Marina; Sakya, Siri A.; Sanford, Sophie; Keeling, Sophie; Tuck, Benjamin J.; Katsinelos, Taxiarchis; Green, Chris; Skov, Lise; Kaalund, Sanne S.; Foss, Stian; Mayes, Keith; 'Connell, Kevin; Wing, Mark; Knox, Claire; Banbury, Jessica; Avezov, Edward; Rowe, James B.; Goedert, Michel; Andersen, Jan Terje; James, Leo C.; McEwan, William A.
作者单位:University of Cambridge; MRC Laboratory Molecular Biology; University of Oslo; University of Oslo; National Hospital Norway; University of Oslo; University of Oslo; University of Oslo; University of Cambridge; University of Copenhagen; Bispebjerg Hospital
摘要:Aggregates of the protein tau are proposed to drive pathogenesis in neurodegenerative diseases. Tau can be targeted by using passively transferred antibodies (Abs), but the mechanisms of Ab protection are incompletely understood. In this work, we used a variety of cell and animal model systems and showed that the cytosolic Ab receptor and E3 ligase TRIM21 (T21) could play a role in Ab protection against tau pathology. Tau-Ab complexes were internalized to the cytosol of neurons, which enabled ...
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作者:Cullen, Thomas M.; Larson, Derek W.; Witton, Mark P.; Scott, Diane; Maho, Tea; Brink, Kirstin S.; Evans, David C.; Reisz, Robert
作者单位:Auburn University System; Auburn University; University of Ottawa; Carleton University; Field Museum of Natural History (Chicago); University of Toronto; University of Portsmouth; Jilin University; Jilin University; University of Toronto; University Toronto Mississauga; University of Manitoba; Royal Ontario Museum
摘要:Large theropod dinosaurs are often reconstructed with their marginal dentition exposed because of the enormous size of their teeth and their phylogenetic association to crocodylians. We tested this hypothesis using a multiproxy approach. Regressions of skull length and tooth size for a range of theropods and extant varanid lizards confirm that complete coverage of theropod dinosaur teeth with extraoral tissues (gingiva and labial scales) is both plausible and consistent with patterns observed ...