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作者：Guillaume, Sophie M.
作者单位：Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite de Rennes
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作者：Zhou, Li; Zhang, Zhen; Shi, Changxia; Scoti, Miriam; Barange, Deepak K.; Gowda, Ravikumar R.; Chen, Eugene Y. -X.
作者单位：Colorado State University System; Colorado State University Fort Collins; University of Naples Federico II
摘要：Polyhydroxyalkanoates (PHAs) have attracted increasing interest as sustainable plastics because of their biorenewability and biodegradability in the ambient environment. However, current semicrystalline PHAs face three long-standing challenges to broad commercial implementation and application: lack of melt processability, mechanical brittleness, and unrealized recyclability, the last of which is essential for achieving a circular plastics economy. Here we report a synthetic PHA platform that ...
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作者：Ge, Yan
作者单位：Northeast Agricultural University - China
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作者：Zecha, Jana; Bayer, Florian P.; Wiechmann, Svenja; Woortman, Julia; Berner, Nicola; Mueller, Julian; Schneider, Annika; Kramer, Karl; Abril-Gil, Mar; Hopf, Thomas; Reichart, Leonie; Chen, Lin; Hansen, Fynn M.; Lechner, Severin; Samaras, Patroklos; Eckert, Stephan; Lautenbacher, Ludwig; Reinecke, Maria; Hamood, Firas; Prokofeva, Polina; Vornholz, Larsen; Falcomata, Chiara; Dorsch, Madeleine; Schroeder, Ayla; Venhuizen, Anton; Wilhelm, Stephanie; Medard, Guillaume; Stoehr, Gabriele; Ruland, Juergen; Gruener, Barbara M.; Saur, Dieter; Buchner, Maike; Ruprecht, Benjamin; Hahne, Hannes; The, Matthew; Wilhelm, Mathias; Kuster, Bernhard
作者单位：Technical University of Munich; Helmholtz Association; German Cancer Research Center (DKFZ); Technical University of Munich; Technical University of Munich; University of Duisburg Essen; Helmholtz Association; German Cancer Research Center (DKFZ); German Center for Infection Research; Max Planck Society
摘要：Although most cancer drugs modulate the activities of cellular pathways by changing posttranslational modifications (PTMs), little is known regarding the extent and the time-and dose-response characteristics of drug-regulated PTMs. In this work, we introduce a proteomic assay called decryptM that quantifies drug-PTM modulation for thousands of PTMs in cells to shed light on target engagement and drug mechanism of action. Examples range from detecting DNA damage by chemotherapeutics, to identif...
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作者：Li, Jinglei; Qu, Wanbo; Daniels, John; Wu, Haijun; Liu, Linjing; Wu, Jie; Wang, Mingwen; Checchia, Stefano; Yang, Shuai; Lei, Haobin; Lv, Rui; Zhang, Yang; Wang, Danyang; Li, Xuexin; Ding, Xiangdong; Sun, Jun; Xu, Zhuo; Chang, Yunfei; Zhang, Shujun; Li, Fei
作者单位：Xi'an Jiaotong University; Xi'an Jiaotong University; Xi'an Jiaotong University; University of New South Wales Sydney; Harbin Institute of Technology; European Synchrotron Radiation Facility (ESRF); Xi'an Jiaotong University; University of Wollongong
摘要：The piezoelectric properties of lead zirconate titanate [Pb(Zr,Ti)O-3 or PZT] ceramics could be enhanced by fabricating textured ceramics that would align the crystal grains along specific orientations. We present a seed-passivated texturing process to fabricate textured PZT ceramics by using newly developed Ba(Zr,Ti)O-3 microplatelet templates. This process not only ensures the template-induced grain growth in titanium-rich PZT layers but also facilitates desired composition through interlaye...
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作者：Offersgaard, Anna; Bukh, Jens; Gottwein, Judith M.
作者单位：University of Copenhagen; University of Copenhagen
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作者：Wagoner, Kaira
作者单位：University of North Carolina; University of North Carolina Greensboro
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作者：Abdul-Ghani, Rashad
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作者：Eker, Sibel
作者单位：Radboud University Nijmegen; International Institute for Applied Systems Analysis (IIASA)
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作者：Waiho, Khor
作者单位：Universiti Malaysia Terengganu
