作者:Owen, Dave
作者单位:University of California System; University of California San Francisco
作者:Seeholzer, Laura
作者单位:University of California System; University of California San Francisco
摘要:Everything that enters our mouth can flow to the lungs or the stomach. Most of the time, things go in the right direction: Air enters the lungs, and food and liquid are shunted to the gastrointestinal tract. However, within an instant, this process can fail. Each time we eat, drink, or sleep, every breath holds the risk of aspirating food, liquid, or stomach acid into our airway. At best, aspiration evokes temporary panic and mild discomfort as we forcefully clear our airways. At worst, it can...
作者:Muir, J.; Anguiano, M.; Kim, C. K.
作者单位:University of California System; University of California Davis; University of California System; University of California Davis
摘要:To determine how neuronal circuits encode and drive behavior, it is often necessary to measure and manipulate different aspects of neurochemical signaling in awake animals. Optogenetics and calcium sensors have paved the way for these types of studies, allowing for the perturbation and readout of spiking activity within genetically defined cell types. However, these methods lack the ability to further disentangle the roles of individual neuromodulator and neuropeptides on circuits and behavior...
作者:Thorp, H. Holden; Vinson, Valda