6720期

最新文章

• Predicting and anticipating rapid evolution AI翻译
  作者：Nosil, Patrik
  作者单位：Centre National de la Recherche Scientifique (CNRS); Centre National de la Recherche Scientifique (CNRS); Universite PSL; Ecole Pratique des Hautes Etudes (EPHE); Universite de Montpellier; Institut de Recherche pour le Developpement (IRD)
• Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function AI翻译
  作者：Swamynathan, Manojit M.; Kuang, Shan; Watrud, Kaitlin E.; Doherty, Mary R.; Gineste, Charlotte; Mathew, Grinu; Gong, Grace Q.; Cox, Hilary; Cheng, Eileen; Reiss, David; Kendall, Jude; Ghosh, Diya; Reczek, Colleen R.; Zhao, Xiang; Herzka, Tali; Spokaite, Saule; Dessus, Antoine N.; Kim, Seung Tea; Klingbeil, Olaf; Liu, Juan; Nowak, Dawid G.; Alsudani, Habeeb; Wee, Tse-Luen; Park, Youngkyu; Minicozzi, Francesca; Rivera, Keith; Almeida, Ana S.; Chang, Kenneth; Chakrabarty, Ram P.; Wilkinson, John E.; Gimotty, Phyllis A.; Diermeier, Sarah D.; Egeblad, Mikala; Vakoc, Christopher R.; Locasale, Jason W.; Chandel, Navdeep S.; Janowitz, Tobias; Hicks, James B.; Wigler, Michael; Pappin, Darryl J.; Williams, Roger L.; Cifani, Paolo; Tuveson, David A.; Laporte, Jocelyn; Trotman, Lloyd C.
  作者单位：Cold Spring Harbor Laboratory; State University of New York (SUNY) System; Stony Brook University; Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Institut National de la Sante et de la Recherche Medicale (Inserm); University of Nebraska System; University of Nebraska Medical Center; MRC Laboratory Molecular Biology; Northwestern University; Feinberg School of Medicine; North Carolina State University; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; NewYork-Presbyterian Hospital; University College Cork; University College Cork; University of Michigan System; University of Michigan; University of Pennsylvania; University of Otago; Johns Hopkins University; University of Southern California
  摘要：Men taking antioxidant vitamin E supplements have increased prostate cancer (PC) risk. However, whether pro-oxidants protect from PC remained unclear. In this work, we show that a pro-oxidant vitamin K precursor [menadione sodium bisulfite (MSB)] suppresses PC progression in mice, killing cells through an oxidative cell death: MSB antagonizes the essential class III phosphatidylinositol (PI) 3-kinase VPS34-the regulator of endosome identity and sorting-through oxidation of key cysteines, point...
• Pacific science academy starts up AI翻译
  作者：Richter, Hannah
• Retractions for Spanish rector AI翻译
  作者：Richter, Hannah
• Multi-omics landscape and molecular basis of radiation tolerance in a tardigrade AI翻译
  作者：Li, Lei; Ge, Zhengping; Liu, Shihao; Zheng, Kun; Li, Yaqi; Chen, Kaiqi; Fu, Yesheng; Lei, Xiaoguang; Cui, Zeling; Wang, Yifan; Huang, Jin; Liu, Yanyan; Duan, Mingwang; Sun, Zimei; Chen, Jun; Li, Liangwei; Shen, Pan; Wang, Guibin; Chen, Junmiao; Li, Ruochong; Li, Chaoran; Yang, Zhixiang; Ning, Yifan; Luo, Arong; Chen, Baoyu; Seim, Inge; Liu, Xin; Wang, Fei; Yao, Yishan; Guo, Fusheng; Yang, Maojun; Liu, Cui Hua; Fan, Guangyi; Wang, Lizhi; Yang, Dong; Zhang, Lingqiang
  作者单位：Qingdao University; Southern Theater Command General Hospital; Peking University; Shenzhen Bay Laboratory; University of South China; Anhui Medical University; Beijing Genomics Institute (BGI); Tsinghua University; Hebei University; Chinese Academy of Sciences; Institute of Zoology, CAS; Shaanxi Xueqian Normal University; Chinese Academy of Sciences; Institute of Deep-Sea Science & Engineering, CAS; Academy of Military Medical Sciences - China; Chinese Academy of Sciences; Institute of Microbiology, CAS
  摘要：Tardigrades are captivating organisms known for their resilience in extreme environments, including ultra-high-dose radiation, but the underlying mechanisms of this resilience remain largely unknown. Using genome, transcriptome, and proteome analysis of Hypsibius henanensis sp. nov., we explored the molecular basis contributing to radiotolerance in this organism. A putatively horizontally transferred gene, DOPA dioxygenase 1 (DODA1), responds to radiation and confers radiotolerance by synthesi...
• Wall of fame AI翻译
  作者：Getzler, Yutan
  作者单位：University System of Ohio; Kenyon College
• Reductive pathways in molten inorganic salts enable colloidal synthesis of III-V semiconductor nanocrystals AI翻译
  作者：Ondry, Justin C.; Zhou, Zirui; Lin, Kailai; Gupta, Aritrajit; Chang, Jun Hyuk; Wu, Haoqi; Jeong, Ahhyun; Hammel, Benjamin F.; Wang, Di; Fry, H. Christopher; Yazdi, Sadegh; Dukovic, Gordana; Schaller, Richard D.; Rabani, Eran; Talapin, Dmitri V.
  作者单位：University of Chicago; University of Chicago; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of Colorado System; University of Colorado Boulder; United States Department of Energy (DOE); Argonne National Laboratory; University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder; Northwestern University; Tel Aviv University; University of Chicago
  摘要：Colloidal quantum dots, with their size-tunable optoelectronic properties and scalable synthesis, enable applications in which inexpensive high-performance semiconductors are needed. Synthesis science breakthroughs have been key to the realization of quantum dot technologies, but important group III-group V semiconductors, including colloidal gallium arsenide (GaAs), still cannot be synthesized with existing approaches. The high-temperature molten salt colloidal synthesis introduced in this wo...
• Open with care AI翻译
  作者：Ravindran, Sandeep
• A genetics gap in biodiversity AI翻译
  作者：Richter, Hannah
• Twenty years of microplastic pollution research-what have we learned? AI翻译
  作者：Thompson, Richard C.; Courtene-Jones, Winnie; Boucher, Julien; Pahl, Sabine; Raubenheimer, Karen; Koelmans, Albert A.
  作者单位：University of Plymouth; University of Vienna; University of Vienna; University of Wollongong; Wageningen University & Research
  摘要：Twenty years after the first publication that used the term microplastic, we review current understanding, refine definitions, and consider future prospects. Microplastics arise from multiple sources, including tires, textiles, cosmetics, paint, and the fragmentation of larger items. They are widely distributed throughout the natural environment, with evidence of harm at multiple levels of biological organization. They are pervasive in food and drink and have been detected throughout the human...