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作者：Brainard, Jeffrey
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作者：Brainard, Jeffrey
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作者：Ma, Jiaqiang; Wu, Yingcheng; Ma, Lifeng; Yang, Xupeng; Zhang, Tiancheng; Song, Guohe; Li, Teng; Gao, Ke; Shen, Xia; Lin, Jian; Chen, Yamin; Liu, Xiaoshan; Fu, Yuting; Gu, Xixi; Chen, Zechuan; Jiang, Shan; Rao, Dongning; Pan, Jiaomeng; Zhang, Shu; Zhou, Jian; Huang, Chen; Shi, Si; Fan, Jia; Guo, Guoji; Zhang, Xiaoming; Gao, Qiang
作者单位：Fudan University; Fudan University; Zhejiang University; Zhejiang University; Chinese Academy of Sciences; Shanghai Institute of Immunity and Infection, CAS; Shanghai Jiao Tong University; Fudan University
摘要：INTRODUCTION Tumor-infiltrating B cells have emerged as important players in cancer immunity and served as predictors of response to immunotherapy. These B cells display multiple functions, primarily through their ability to differentiate into plasma cells to produce antibodies, but vary spatiotemporally across different cancer types. Dissecting the abundance and differentiation states of B cells across diverse cancer types holds promise for improving the immunotherapeutic response. RATIONALE ...
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作者：Ortega, Rodrigo Perez
摘要：If elected, Claudia Sheinbaum Pardo would bring an extensive background in science and engineering to Mexico's presidency. But many researchers are anxious about how she would govern
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作者：Khan, Tauheed Ullah; Ahmad, Shahid
作者单位：Guangdong Academy of Sciences; Institute of Zoology, Guangdong Academy of Sciences; Hainan University
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作者：Li, Peiyun; Sun, Wenxi; Li, Jiulong; Chen, Ju-Peng; Wang, Xinyue; Mei, Zi; Jin, Guanyu; Lei, Yuqiu; Xin, Ruiyun; Yang, Mo; Xu, Jingcao; Pan, Xiran; Song, Cheng; Deng, Xin-Yu; Lei, Xun; Liu, Kai; Wang, Xiu; Zheng, Yuting; Zhu, Jia; Lv, Shixian; Zhang, Zhi; Dai, Xiaochuan; Lei, Ting
作者单位：Peking University; Tsinghua University; Peking University; Peking University; Chinese Academy of Sciences; National Center for Nanoscience & Technology, CAS
摘要：Hydrogels are an attractive category of biointerfacing materials with adjustable mechanical properties, diverse biochemical functions, and good ionic conductivity. Despite these advantages, their application in electronics has been restricted because of their lack of semiconducting properties, and they have traditionally only served as insulators or conductors. We developed single- and multiple-network hydrogels based on a water-soluble n-type semiconducting polymer, endowing conventional hydr...
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作者：Brainard, Jeffrey
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作者：Carlton, Jane M.; Cunnington, Aubrey J.
作者单位：Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Imperial College London
摘要：Natural infections are distinct from those of laboratory-or zombie-strains Considered one of the big three global infectious diseases-together with HIV/AIDS and tuberculosis-malaria caused by Plasmodium falciparum and Plasmodium vivax continues to substantially affect the poorest communities of sub-Saharan Africa and Southeast Asia (1). Development of resistance to almost all antimalarial drugs by the parasite, resistance of the Anopheles mosquito (which transmits the parasite) to commonly use...
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作者：Cohen, Jon; Enserink, Martin
摘要：New measures to control H5N1 in cows are a drop in the bucket, scientists say
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作者：Kumar, Arun; Vaca-Dempere, Mireia; Mortimer, Thomas; Deryagin, Oleg; Smith, Jacob G.; Petrus, Paul; Koronowski, Kevin B.; Greco, Carolina M.; Segales, Jessica; Andres, Eva; Lukesova, Vera; Zinna, Valentina M.; Welz, Patrick-Simon; Serrano, Antonio L.; Perdiguero, Eusebio; Sassone-Corsi, Paolo; Benitah, Salvador Aznar; Munoz-Canoves, Pura
作者单位：Pompeu Fabra University; Barcelona Institute of Science & Technology; Institute for Research in Biomedicine - IRB Barcelona; University of Texas System; University of Texas at San Antonio; Karolinska Institutet; Humanitas University; Hospital del Mar Research Institute; Hospital del Mar; ICREA
摘要：A molecular clock network is crucial for daily physiology and maintaining organismal health. We examined the interactions and importance of intratissue clock networks in muscle tissue maintenance. In arrhythmic mice showing premature aging, we created a basic clock module involving a central and a peripheral (muscle) clock. Reconstituting the brain-muscle clock network is sufficient to preserve fundamental daily homeostatic functions and prevent premature muscle aging. However, achieving whole...
