2024

最新文章

• Antibiotics overused in pandemic AI翻译
  作者：Brainard, Jeffrey
• Darwin meets Dickinson The biologist and the poet shared deep sensibilities about the natural world AI翻译
  作者：Mondello, Kaitlin; Dickinson, Emily; Darwin, Charles
  作者单位：Pennsylvania State System of Higher Education (PASSHE); Millersville University of Pennsylvania
  摘要：The biologist and the poet shared deep sensibilities about the natural world
• Climbing out of the pit AI翻译
  作者：Hart, Will
  作者单位：University of Virginia
• Conductive hydrogels put electrons in charge AI翻译
  作者：Gao, Dace; Fabiano, Simone
  作者单位：Linkoping University
  摘要：Semiconductor hydrogels enable active bioelectronics
• Human telomere length is chromosome end-specific and conserved across individuals AI翻译
  作者：Karimian, Kayarash; Groot, Aljona; Huso, Vienna; Kahidi, Ramin; Tan, Kar-Tong; Sholes, Samantha; Keener, Rebecca; McDyer, John F.; Alder, Jonathan K.; Li, Heng; Rechtsteiner, Andreas; Greider, Carol W.
  作者单位：Johns Hopkins University; Johns Hopkins University; University of California System; University of California Santa Cruz; University of Calgary; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Johns Hopkins University; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard Medical School; Merck & Company; Merck & Company USA
  摘要：Short telomeres cause age-related disease, and long telomeres contribute to cancer; however, the mechanisms regulating telomere length are unclear. We developed a nanopore-based method, which we call Telomere Profiling, to determine telomere length at nearly single-nucleotide resolution. Mapping telomere reads to chromosome ends showed chromosome end-specific length distributions that could differ by more than six kilobases. Examination of telomere lengths in 147 individuals revealed that cert...
• A pandemic agreement is within reach AI翻译
  作者：Cicero, Anita; Phelan, Alexandra
  作者单位：Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health
  摘要：At the end of May, 194 member states of the World Health Organization (WHO) will meet for the World Health Assembly. Negotiations underway now will determine whether they vote then to adopt a pandemic agreement. For the past 2 years, discussions have focused on articulating essential components of a robust and equitable architecture for pandemic preparedness and response. Despite this, talks have failed to produce sufficient consensus on a detailed draft, prompting the intergovernmental negoti...
• Noncharismatic species also need protection AI翻译
  作者：Xing, Daochao; Gouveia, Ana; Huang, Yuxiong; Chen, Ciara Chun; Zhu, Xiaoshan
  作者单位：Tsinghua University; Shantou University; Hainan University
• Bacteria could tame plastic waste AI翻译
  作者：Brainard, Jeffrey
• A single cell atlas of sexual development in Plasmodium falciparum AI翻译
  作者：Dogga, Sunil Kumar; Rop, Jesse C.; Cudini, Juliana; Farr, Elias; Dara, Antoine; Ouologuem, Dinkorma; Djimde, Abdoulaye A.; Talman, Arthur M.; Lawniczak, Mara K. N.
  作者单位：Wellcome Trust Sanger Institute; Ruprecht Karls University Heidelberg; University of Science & Technology of Bamako; Institut de Recherche pour le Developpement (IRD); Universite de Montpellier; Centre National de la Recherche Scientifique (CNRS)
  摘要：The developmental decision made by malaria parasites to become sexual underlies all malaria transmission. Here, we describe a rich atlas of short- and long-read single-cell transcriptomes of over 37,000 Plasmodium falciparum cells across intraerythrocytic asexual and sexual development. We used the atlas to explore transcriptional modules and exon usage along sexual development and expanded it to include malaria parasites collected from four Malian individuals naturally infected with multiple ...
• Atomic physics on a 50-nm scale: Realization of a bilayer system of dipolar atoms AI翻译
  作者：Du, Li; Barral, Pierre; Cantara, Michael; de Hond, Julius; Lu, Yu-Kun; Ketterle, Wolfgang
  作者单位：Massachusetts Institute of Technology (MIT); Amazon.com
  摘要：Controlling ultracold atoms with laser light has greatly advanced quantum science. The wavelength of light sets a typical length scale for most experiments to the order of 500 nanometers (nm) or greater. In this work, we implemented a super-resolution technique that localizes and arranges atoms on a sub-50-nm scale, without any fundamental limit in resolution. We demonstrate this technique by creating a bilayer of dysprosium atoms and observing dipolar interactions between two physically separ...