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作者:Samaniego, Luis
作者单位:Helmholtz Association; Helmholtz Center for Environmental Research (UFZ); University of Potsdam
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作者:Cohen, Jon
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作者:Canesso, Maria Cecilia Campos; de Castro, Tiago Bruno Rezende; Nakandakari-Higa, Sandra; Lockhart, Ainsley; Luehr, Julia; Bortolatto, Juliana; Parsa, Roham; Esterhazy, Daria; Lyu, Mengze; Liu, Tian-Tian; Murphy, Kenneth M.; Sonnenberg, Gregory F.; Reis, Bernardo S.; Victora, Gabriel D.; Mucida, Daniel
作者单位:Rockefeller University; Rockefeller University; University of Chicago; Cornell University; Weill Cornell Medicine; Washington University (WUSTL); Rockefeller University; Howard Hughes Medical Institute
摘要:The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal antigens to CD4+ T cells and inducing their differentiation into regulatory (peripheral regulatory T cell) or inflammatory [T helper (Th) cell] subsets. We used a proximity labeling method (LIPSTIC) to identify APCs that presented dietary antigens under tolerizing and inflammatory conditions and to u...
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作者:Gibbons, Ann
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作者:Riel, Bryan
作者单位:Zhejiang University
摘要:A deep-learning model infers large-scale dynamics of Antarctic ice shelves
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作者:O'Grady, Cathleen
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作者:Spezio, Michael
作者单位:Claremont Colleges; Scripps College
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作者:Brown, Zachary; Reisig, Dominic
作者单位:North Carolina State University; North Carolina State University; North Carolina State University
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作者:Navarrete Mendez, Maria Jose; Mena Gonzalez, Gabriela; Ochoa Ochoa, Leticia M.
作者单位:University of California System; University of California Berkeley; Universidad San Francisco de Quito; Universidad Nacional Autonoma de Mexico
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作者:Sun, Wenjian; Zhang, Guang-Wei; Huang, Junxiang J.; Tao, Can; Seo, Michelle B.; Tao, Huizhong Whit; Zhang, Li I.
作者单位:University of Southern California; University of Southern California; University of Southern California; University of Southern California
摘要:Whereas humans exhibit emergency responses to assist unconscious individuals, how nonhuman animals react to unresponsive conspecifics is less well understood. We report that mice exhibit stereotypic behaviors toward unconscious or dead social partners, which escalate from sniffing and grooming to more forceful actions such as mouth or tongue biting and tongue pulling. The latter intense actions, more prominent in familiar pairs, begin after prolonged immobility and unresponsiveness and cease w...