2025

最新文章

• Fungal small RNAs suppress plant immunity by hijacking host RNA interference pathways (Vol 342, pg 118, 2013) AI翻译
  作者：Weinberg, A.
• Buried salt is abetting Arctic thaw AI翻译
  作者：Appenzeller, Tim
• Earthquakes in the blind spot AI翻译
  作者：Brodsky, Emily E.; Ruiz, Sergio
  作者单位：University of California System; University of California Santa Cruz; Universidad de Chile
• The vitality of old age AI翻译
  作者：Goldman, Michael A.
  作者单位：California State University System; San Francisco State University
• What if NIH had been 40% smaller? AI翻译
  作者：Azoulay, Pierre; Clancy, Matthew; Li, Danielle; Sampat, Bhaven N.
  作者单位：Massachusetts Institute of Technology (MIT); National Bureau of Economic Research; Johns Hopkins University; Johns Hopkins University
• An inheritance of long life AI翻译
  作者：Bohnert, K. Adam
  作者单位：Louisiana State University System; Louisiana State University
• Corporate tourism threatens protected areas AI翻译
  作者：O'Bryan, Christopher J.; Allan, James R.; Dapash, Meitamei Ole
  作者单位：Maastricht University
• What to Expect When You're Dead: An Ancient Tour of Death and the Afterlife AI翻译
  作者：Riedl, Rachel Beatty
  作者单位：Cornell University
• Identification of short-range ordering motifs in semiconductors AI翻译
  作者：Vogl, Lilian M.; Chen, Shunda; Schweizer, Peter; Jin, Xiaochen; Yu, Shui-Qing; Liu, Jifeng; Li, Tianshu; Minor, Andrew M.
  作者单位：University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; George Washington University; University of Arkansas System; University of Arkansas Fayetteville; Dartmouth College
  摘要：Chemical short-range ordering is expected to be a key factor for tuning the electronic structure of semiconductors. However, experimental evidence of short-range ordering is still lacking due to the challenge of characterizing atomic-scale ordering motifs. Here, we determined the presence of short-range order in a ternary GeSiSn semiconductor system using advanced energy-filtered four-dimensional scanning transmission electron microscopy and large-scale atomistic models generated by a machine ...
• Dynamic U2AF cycling defines two phases of cotranscriptional pre-mRNA splicing AI翻译
  作者：Shao, Changwei; Hao, Yajing; Jiang, Li; Wang, Dong; Wang, Rui; Li, Yuanjun; Wang, Hui; Ge, Yaping; Bai, Rui; Du, Xiangjuan; Chen, Xizi; Wu, Tan; Gou, Lan-Tao; Wan, Ruixue; Xu, Yanhui; Ji, Xiong; Fu, Xiang-Dong
  作者单位：Westlake Laboratory; Westlake University; Westlake University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Beijing Institute of Genomics, CAS; University of California System; University of California San Diego; Peking University; Fudan University; Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS
  摘要：Distinguishing functional splice sites from abundant cryptic sites in precursor messenger RNAs (pre-mRNAs) represents a fundamental challenge in decoding mammalian genomes. We demonstrate that the specific RNA polymerase II (Pol II) subunit RPB9 directly interacts with the 3 ' AG dinucleotide binding factor U2AF1 to initiate 3 ' splice site recognition. Combined with recent structural insights into Pol II-mediated 5 ' splice site selection, these findings support a cotranscriptional mechanism ...