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作者:Ewbank, Jonathan
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作者:Reglade, U.; Bocquet, A.; Gautier, R.; Cohen, J.; Marquet, A.; Albertinale, E.; Pankratova, N.; Hallen, M.; Rautschke, F.; Sellem, L. -A.; Rouchon, P.; Sarlette, A.; Mirrahimi, M.; Campagne-Ibarcq, P.; Lescanne, R.; Jezouin, S.; Leghtas, Z.
作者单位:Inria; Sorbonne Universite; Universite Paris Cite; Universite PSL; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Ecole Normale Superieure de Lyon (ENS de LYON); Centre National de la Recherche Scientifique (CNRS)
摘要:Quantum bits (qubits) are prone to several types of error as the result of uncontrolled interactions with their environment. Common strategies to correct these errors are based on architectures of qubits involving daunting hardware overheads(1). One possible solution is to build qubits that are inherently protected against certain types of error, so the overhead required to correct the remaining errors is greatly reduced(2-7). However, this strategy relies on one condition: any quantum manipul...
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作者:Diaz, Nuria; Perez, Carlos; Escribano, Ana Maria; Sanz, Gema; Priego, Julian; Lafuente, Celia; Barberis, Mario; Calle, Luis; Espinosa, Juan Felix; Priest, Birgit T.; Zhang, Hong Y.; Nosie, Amanda K.; Haas, Joseph V.; Cannady, Ellen; Borel, Anthony; Schultze, Albert E.; Sauder, J. Michael; Hendle, Joerg; Weichert, Ken; Nicholls, Stephen J.; Michael, Laura F.
作者单位:Eli Lilly; Lilly Research Laboratories; Eli Lilly; Lilly Research Laboratories; Eli Lilly; Lilly Research Laboratories; Monash University
摘要:Lipoprotein(a) (Lp(a)), an independent, causal cardiovascular risk factor, is a lipoprotein particle that is formed by the interaction of a low-density lipoprotein (LDL) particle and apolipoprotein(a) (apo(a))(1,2). Apo(a) first binds to lysine residues of apolipoprotein B-100 (apoB-100) on LDL through the Kringle IV (K-IV) 7 and 8 domains, before a disulfide bond forms between apo(a) and apoB-100 to create Lp(a) (refs. 3-7). Here we show that the first step of Lp(a) formation can be inhibited...
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作者:Warren, Audrey L.; Lankri, David; Cunningham, Michael J.; Serrano, Inis C.; Parise, Lyonna F.; Kruegel, Andrew C.; Duggan, Priscilla; Zilberg, Gregory; Capper, Michael J.; Havel, Vaclav; Russo, Scott J.; Sames, Dalibor; Wacker, Daniel
作者单位:Icahn School of Medicine at Mount Sinai; Columbia University; Icahn School of Medicine at Mount Sinai; Columbia University
摘要:Psychedelic substances such as lysergic acid diethylamide (LSD) and psilocybin show potential for the treatment of various neuropsychiatric disorders1-3. These compounds are thought to mediate their hallucinogenic and therapeutic effects through the serotonin (5-hydroxytryptamine (5-HT)) receptor 5-HT2A (ref. 4). However, 5-HT1A also plays a part in the behavioural effects of tryptamine hallucinogens5, particularly 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), a psychedelic found in the toxin ...
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作者:Conroy, Gemma
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作者:Zhou, Sai; Gao, Xiaoxiang; Park, Geonho; Yang, Xinyi; Qi, Baiyan; Lin, Muyang; Huang, Hao; Bian, Yizhou; Hu, Hongjie; Chen, Xiangjun; Wu, Ray S.; Liu, Boyu; Yue, Wentong; Lu, Chengchangfeng; Wang, Ruotao; Bheemreddy, Pranavi; Qin, Siyu; Lam, Arthur; Wear, Keith A.; Andre, Michael; Kistler, Erik B.; Newell, David W.; Xu, Sheng
作者单位:University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; US Food & Drug Administration (FDA); University of California System; University of California San Diego; University of California System; University of California San Diego
摘要:Accurate and continuous monitoring of cerebral blood flow is valuable for clinical neurocritical care and fundamental neurovascular research. Transcranial Doppler (TCD) ultrasonography is a widely used non-invasive method for evaluating cerebral blood flow(1), but the conventional rigid design severely limits the measurement accuracy of the complex three-dimensional (3D) vascular networks and the practicality for prolonged recording(2). Here we report a conformal ultrasound patch for hands-fre...
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作者:[Anonymous]
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作者:Riris, Philip; Silva, Fabio; Crema, Enrico; Palmisano, Alessio; Robinson, Erick; Siegel, Peter E.; French, Jennifer C.; Jorgensen, Erlend Kirkeng; Maezumi, Shira Yoshi; Solheim, Steinar; Bates, Jennifer; Davies, Benjamin; Oh, Yongje; Ren, Xiaolin
作者单位:Bournemouth University; University of Cambridge; University of Turin; Nevada System of Higher Education (NSHE); Desert Research Institute NSHE; Arizona State University; Arizona State University-Tempe; Montclair State University; University of Liverpool; Max Planck Society; University of Oslo; Seoul National University (SNU); Tufts University; Chinese Academy of Sciences; Institute for the History of Natural Science, CAS
摘要:The record of past human adaptations provides crucial lessons for guiding responses to crises in the future 1-3 . To date, there have been no systematic global comparisons of humans' ability to absorb and recover from disturbances through time 4,5 . Here we synthesized resilience across a broad sample of prehistoric population time-frequency data, spanning 30,000 years of human history. Cross-sectional and longitudinal analyses of population decline show that frequent disturbances enhance a po...
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作者:Bardgett, Richard D.
作者单位:University of Manchester
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作者:Conlon, Anne Marie
摘要:Researchers find ways to interweave faith and science, from discussing Ramadan fasts with colleagues to applying religious parables to lab work.