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作者:Gibney, Elizabeth; Wild, Sarah
摘要:Labour Prime Minister Keir Starmer has placed several experts who aren't politicians into government posts.
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作者:[Anonymous]
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作者:[Anonymous]
摘要:The location of an injury determines whether ants bite off or preserve a damaged limb.
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作者:Lesser, Ellen; Azevedo, Anthony W.; Phelps, Jasper S.; Elabbady, Leila; Cook, Andrew; Syed, Durafshan Sakeena; Mark, Brandon; Kuroda, Sumiya; Sustar, Anne; Moussa, Anthony; Dallmann, Chris J.; Agrawal, Sweta; Lee, Su-Yee J.; Pratt, Brandon; Skutt-Kakaria, Kyobi; Gerhard, Stephan; Lu, Ran; Kemnitz, Nico; Lee, Kisuk; Halageri, Akhilesh; Castro, Manuel; Ih, Dodam; Gager, Jay; Tammam, Marwan; Dorkenwald, Sven; Collman, Forrest; Schneider-Mizell, Casey; Brittain, Derrick; Jordan, Chris S.; Macrina, Thomas; Dickinson, Michael; Lee, Wei-Chung Allen; Tuthill, John C.
作者单位:University of Washington; University of Washington Seattle; Harvard University; Harvard Medical School; University of California System; University of California Santa Barbara; California Institute of Technology; Princeton University; Princeton University; Allen Institute for Brain Science; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Boston Children's Hospital; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要:Animal movement is controlled by motor neurons (MNs), which project out of the central nervous system to activate muscles(1). MN activity is coordinated by complex premotor networks that facilitate the contribution of individual muscles to many different behaviours(2-6). Here we use connectomics(7) to analyse the wiring logic of premotor circuits controlling the Drosophila leg and wing. We find that both premotor networks cluster into modules that link MNs innervating muscles with related func...
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作者:Hautzinger, Matthew P.; Pan, Xin; Hayden, Steven C.; Ye, Jiselle Y.; Jiang, Qi; Wilson, Mickey J.; Phillips, Alan J.; Dong, Yifan; Raulerson, Emily K.; Leahy, Ian A.; Jiang, Chun-Sheng; Blackburn, Jeffrey L.; Luther, Joseph M.; Lu, Yuan; Jungjohann, Katherine; Vardeny, Z. Valy; Berry, Joseph J.; Alberi, Kirstin; Beard, Matthew C.
作者单位:United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; Utah System of Higher Education; University of Utah; Colorado School of Mines; University of Colorado System; University of Colorado Boulder; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite de Lorraine; University of Colorado System; University of Colorado Boulder
摘要:Spin accumulation in semiconductor structures at room temperature and without magnetic fields is key to enable a broader range of optoelectronic functionality1. Current efforts are limited owing to inherent inefficiencies associated with spin injection across semiconductor interfaces2. Here we demonstrate spin injection across chiral halide perovskite/III-V interfaces achieving spin accumulation in a standard semiconductor III-V (AlxGa1-x)0.5In0.5P multiple quantum well light-emitting diode. T...
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作者:Bigagli, Niccolo; Yuan, Weijun; Zhang, Siwei; Bulatovic, Boris; Karman, Tijs; Stevenson, Ian; Will, Sebastian
作者单位:Columbia University; Radboud University Nijmegen
摘要:Ensembles of particles governed by quantum mechanical laws exhibit intriguing emergent behaviour. Atomic quantum gases(1,2), liquid helium(3,4) and electrons in quantum materials(5-7) all exhibit distinct properties because of their composition and interactions. Quantum degenerate samples of ultracold dipolar molecules promise the realization of new phases of matter and new avenues for quantum simulation(8) and quantum computation(9). However, rapid losses(10), even when reduced through collis...
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作者:Coban, Ivo; Lamping, Jan-Philipp; Hirsch, Anna Greta; Wasilewski, Sarah; Shomroni, Orr; Giesbrecht, Oliver; Salinas, Gabriela; Krebber, Heike
作者单位:University of Gottingen; University of Gottingen; UNIVERSITY GOTTINGEN HOSPITAL
摘要:When mRNAs have been transcribed and processed in the nucleus, they are exported to the cytoplasm for translation. This export is mediated by the export receptor heterodimer Mex67-Mtr2 in the yeast Saccharomyces cerevisiae (TAP-p15 in humans)(1,2). Interestingly, many long non-coding RNAs (lncRNAs) also leave the nucleus but it is currently unclear why they move to the cytoplasm(3). Here we show that antisense RNAs (asRNAs) accelerate mRNA export by annealing with their sense counterparts thro...
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作者:Goverde, Casper A.; Pacesa, Martin; Goldbach, Nicolas; Dornfeld, Lars J.; Balbi, Petra E. M.; Georgeon, Sandrine; Rosset, Stephane; Kapoor, Srajan; Choudhury, Jagrity; Dauparas, Justas; Schellhaas, Christian; Kozlov, Simon; Baker, David; Ovchinnikov, Sergey; Vecchio, Alex J.; Correia, Bruno E.
作者单位:State University of New York (SUNY) System; University at Buffalo, SUNY; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; Massachusetts Institute of Technology (MIT); University of Washington; University of Washington Seattle; Howard Hughes Medical Institute
摘要:De novo design of complex protein folds using solely computational means remains a substantial challenge 1 . Here we use a robust deep learning pipeline to design complex folds and soluble analogues of integral membrane proteins. Unique membrane topologies, such as those from G-protein-coupled receptors 2 , are not found in the soluble proteome, and we demonstrate that their structural features can be recapitulated in solution. Biophysical analyses demonstrate the high thermal stability of the...
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作者:[Anonymous]
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作者:Chomaz, Lauriane
作者单位:Ruprecht Karls University Heidelberg
摘要:A gas of molecules that interact over long distances has been cooled to mere nanokelvins, resulting in the emergence of a state known as a Bose-Einstein condensate - the first of its kind in this type of molecular system.