作者：Wang, Chuchu; Jiang, Wenhong; Leitz, Jeremy; Yang, Kailu; Esquivies, Luis; Wang, Xing; Shen, Xiaotao; Held, Richard G.; Adams, Daniel J.; Basta, Tamara; Hampton, Lucas; Jian, Ruiqi; Jiang, Lihua; Stowell, Michael H. B.; Baumeister, Wolfgang; Guo, Qiang; Brunger, Axel T.
作者单位：Stanford University; Stanford University; Stanford University; Stanford University; Stanford University; Howard Hughes Medical Institute; Peking University; Peking University; Stanford University; Stanford University; Nanyang Technological University; University of Colorado System; University of Colorado Boulder; Max Planck Society
摘要：Synaptic vesicles are organelles with a precisely defined protein and lipid composition1,2, yet the molecular mechanisms for the biogenesis of synaptic vesicles are mainly unknown. Here we discovered a well-defined interface between the synaptic vesicle V-ATPase and synaptophysin by in situ cryo-electron tomography and single-particle cryo-electron microscopy of functional synaptic vesicles isolated from mouse brains3. The synaptic vesicle V-ATPase is an ATP-dependent proton pump that establis...
作者：Fang, Zizheng; Mu, Hongfeng; Sun, Zhuo; Zhang, Kaihang; Zhang, Anyang; Chen, Jiada; Zheng, Ning; Zhao, Qian; Yang, Xuxu; Liu, Feng; Wu, Jingjun; Xie, Tao
作者单位：Zhejiang University; Zhejiang University; Zhejiang University; Shanghai Jiao Tong University; Zhejiang University
摘要：Three-dimensional (3D) printing has emerged as an attractive manufacturing technique because of its exceptional freedom in accessing geometrically complex customizable products. Its potential for mass manufacturing, however, is hampered by its low manufacturing efficiency (print speed) and insufficient product quality (mechanical properties). Recent progresses in ultra-fast 3D printing of photo-polymers1-5 have alleviated the issue of manufacturing efficiency, but the mechanical performance of...
作者：Bader, Jackie E.; Wolf, Melissa M.; Lupica-Tondo, Gian Luca; Madden, Matthew Z.; Reinfeld, Bradley I.; Arner, Emily N.; Hathaway, Emma S.; Steiner, KayLee K.; Needle, Gabriel A.; Hatem, Zaid; Landis, Madelyn D.; Faneuff, Eden E.; Blackman, Amondrea; Wolf, Elysa M.; Cottam, Matthew A.; Ye, Xiang; Bates, Madison E.; Smart, Kyra; Wang, Wenjun; Pinheiro, Laura V.; Christofides, Anthos; Smith, Dupreez; Boussiotis, Vassiliki A.; Haake, Scott M.; Beckermann, Kathryn E.; Wellen, Kathryn E.; Reinhart-King, Cynthia A.; Serezani, C. Henrique; Lee, Cheng-Han; Aubrey, Christa; Chen, Heidi; Rathmell, W. Kimryn; Hasty, Alyssa H.; Rathmell, Jeffrey C.
作者单位：Vanderbilt University; Vanderbilt University; Vanderbilt University; Vanderbilt University; Vanderbilt University; Vanderbilt University; University of Pennsylvania; Harvard University; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Harvard Medical School; University of Alberta; Vanderbilt University; University of Pennsylvania; University of Alberta; Vanderbilt University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Tennessee Valley Healthcare System
作者：Ewers, Robert M.; Orme, C. David L.; Pearse, William D.; Zulkifli, Nursyamin; Yvon-Durocher, Genevieve; Yusah, Kalsum M.; Yoh, Natalie; Yeo, Darren C. J.; Wong, Anna; Williamson, Joseph; Wilkinson, Clare L.; Wiederkehr, Fabienne; Webber, Bruce L.; Wearn, Oliver R.; Wai, Leona; Vollans, Maisie; Twining, Joshua P.; Turner, Edgar C.; Tobias, Joseph A.; Thorley, Jack; Telford, Elizabeth M.; Teh, Yit Arn; Tan, Heok Hui; Swinfield, Tom; Svatek, Martin; Struebig, Matthew; Stork, Nigel; Sleutel, Jani; Slade, Eleanor M.; Sharp, Adam; Shabrani, Adi; Sethi, Sarab S.; Seaman, Dave J. I.; Sawang, Anati; Roxby, Gabrielle Briana; Rowcliffe, J. Marcus; Rossiter, Stephen J.; Riutta, Terhi; Rahman, Homathevi; Qie, Lan; Psomas, Elizabeth; Prairie, Aaron; Poznansky, Frederica; Pillay, Rajeev; Picinali, Lorenzo; Pianzin, Annabel; Pfeifer, Marion; Parrett, Jonathan M.; Noble, Ciar D.; Nilus, Reuben; Mustaffa, Nazirah; Mullin, Katherine E.; Mitchell, Simon; Mckinlay, Amelia R.; Maunsell, Sarah; Matula, Radim; Massam, Michael; Martin, Stephanie; Malhi, Yadvinder; Majalap, Noreen; Maclean, Catherine S.; Mackintosh, Emma; Luke, Sarah H.; Lewis, Owen T.; Layfield, Harry J.; lane-Shaw, IsolDe; Kueh, Boon Hee; Kratina, Pavel; Konopik, Oliver; Kitching, Roger; Kinneen, Lois; Kemp, Victoria A.; Jotan, Palasiah; Jones, Nick; Jebrail, Evyen W.; Hrones, Michal; Heon, Sui Peng; Hemprich-Bennett, David R.; Haysom, Jessica K.; Harianja, Martina F.; Hardwick, Jane; Gregory, Nichar; Gray, Ryan; Gray, Ross E. J.; Granville, Natasha; Gill, Richard; Fraser, Adam; Foster, William A.; Folkard-Tapp, Hollie; Fletcher, Robert J.; Fikri, Arman Hadi; Fayle, Tom M.; Faruk, Aisyah; Eggleton, Paul; Edwards, David P.; Drinkwater, Rosie; Dow, Rory A.; Dobert, Timm F.; Didham, Raphael K.; Dickinson, Katharine J. M.; Deere, Nicolas J.; de Lorm, Tijmen; Dawood, Mahadimenakbar M.; Davison, Charles W.; Davies, Zoe G.; Davies, Richard G.; Dancak, Martin; Cusack, Jeremy; Clare, Elizabeth L.; Chung, Arthur; Chey, Vun Khen; Chapman, Philip M.; Cator, Lauren; Carpenter, Daniel; Carbone, Chris; Calloway, Kerry; Bush, Emma R.; Burslem, David F. R. P.; Brown, Keiron D.; Brooks, Stephen J.; Brasington, Ella; Brant, Hayley; Boyle, Michael J. W.; Both, Sabine; Blackman, Joshua; Bishop, Tom R.; Bicknell, Jake E.; Bernard, Henry; Basrur, Saloni; Barclay, Maxwell V. L.; Barclay, Holly; Atton, Georgina; Ancrenaz, Marc; Aldridge, David C.; Daniel, Olivia Z.; Reynolds, Glen; Banks-Leite, Cristina
作者单位：Imperial College London; Universiti Putra Malaysia; University of Bristol; Universiti Malaysia Sabah; Royal Botanic Gardens, Kew; University of Kent; University of Wisconsin System; University of Wisconsin Madison; National University of Singapore; National University of Singapore; University of London; Queen Mary University London; University of London; University College London; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Western Australia; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Health & Biosecurity; University of Oxford; Cornell University; University of Cambridge; University of Edinburgh; Newcastle University - UK; Mendel University in Brno; Griffith University; Vrije Universiteit Brussel; Nanyang Technological University; University of Montana System; University of Montana; World Wildlife Fund; University of Cambridge; Zoological Society of London; University of Oxford; University of Exeter; University of Lincoln; Colorado State University System; Colorado State University Fort Collins; University of Exeter; State University System of Florida; University of Florida; University of Northern British Columbia; Imperial College London; Adam Mickiewicz University; University of East Anglia; Pusat Penyelidikan Hutan; Griffith University; Czech University of Life Sciences Prague; University of Sheffield; University of the Sunshine Coast; University of Nottingham; University of East Anglia; University of Bristol; Laval University; University of Wurzburg; University of Reading; Imperial College London; Palacky University Olomouc; EcoHealth Alliance; Czech Academy of Sciences; Biology Centre of the Czech Academy of Sciences; Royal Botanic Gardens, Kew; Natural History Museum London; University of Sheffield; University of Malaysia Sarawak; Naturalis Biodiversity Center; University of Alberta; University of Otago; Aarhus University; Aarhus University; Palacky University Olomouc; York University - Canada; Royal Botanic Gardens, Kew; University of Aberdeen; University of Hong Kong; University of New England; University of Pretoria; Cardiff University; Monash University; Monash University Malaysia; University of Bristol
摘要：Logged and disturbed forests are often viewed as degraded and depauperate environments compared with primary forest. However, they are dynamic ecosystems(1) that provide refugia for large amounts of biodiversity2,3, so we cannot afford to underestimate their conservation value4. Here we present empirically defined thresholds for categorizing the conservation value of logged forests, using one of the most comprehensive assessments of taxon responses to habitat degradation in any tropical forest...
