8026期

最新文章

• Transport and inhibition mechanisms of the human noradrenaline transporter AI翻译
  作者：Hu, Tuo; Yu, Zhuoya; Zhao, Jun; Meng, Yufei; Salomon, Kristine; Bai, Qinru; Wei, Yiqing; Zhang, Jinghui; Xu, Shujing; Dai, Qiuyun; Yu, Rilei; Yang, Bei; Loland, Claus J.; Zhao, Yan
  作者单位：Chinese Academy of Sciences; Institute of Biophysics, CAS; Chinese Academy of Sciences; Institute of Biophysics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Peking University; University of Copenhagen; Ocean University of China; Capital Medical University; Capital Medical University
  摘要：The noradrenaline transporter (also known as norepinephrine transporter) (NET) has a critical role in terminating noradrenergic transmission by utilizing sodium and chloride gradients to drive the reuptake of noradrenaline (also known as norepinephrine) into presynaptic neurons(1-3). It is a pharmacological target for various antidepressants and analgesic drugs(4,5). Despite decades of research, its structure and the molecular mechanisms underpinning noradrenaline transport, coupling to ion gr...
• How to win funding to talk about your science AI翻译
  作者：Docter-Loeb, Hannah
  摘要：Many researchers describe public outreach as a labour of love, often carried out in their spare time. But some funders reward these activities.
• Superconductivity paper spurs dispute as field reels from earlier scandal AI翻译
  作者：Garisto, Dan
  摘要：Whistleblowers raise questions about the processing and sharing of raw data.
• Task switching can make AI lose the ability to learn AI翻译
  作者：Lyle, Clare; Pascanu, Razvan
  作者单位：Alphabet Inc.; DeepMind; Alphabet Inc.; Google Incorporated; DeepMind
• The Amazon is relinquishing its carbon - for a surprising reason AI翻译
  作者：[Anonymous]
  摘要：Degradation of the Amazon's tree canopy is the main culprit, although the complete clearance of portions of the forest contributes too.
• What will it take to open South Korean research to the world? AI翻译
  作者：Rashid, Raphael
  摘要：Efforts to join the global ecosystem depend on greater diversity and a more open culture.
• The catalytic asymmetric polyene cyclization of homofarnesol to ambrox AI翻译
  作者：Luo, Na; Turberg, Mathias; Leutzsch, Markus; Mitschke, Benjamin; Brunen, Sebastian; Wakchaure, Vijay N.; Noethling, Nils; Schelwies, Mathias; Pelzer, Ralf; List, Benjamin
  作者单位：Max Planck Society; BASF; BASF
  摘要：Polyene cyclizations are among the most complex and challenging transformations in biology. In a single reaction step, multiple carbon-carbon bonds, ring systems and stereogenic centres are constituted from simple, acyclic precursors(1-3). Simultaneously achieving this kind of precise control over product distribution and stereochemistry poses a formidable task for chemists. In particular, the polyene cyclization of (3E,7E)-homofarnesol to the valuable naturally occurring ambergris odorant (-)...
• Hydrogen sulfide and metal-enriched atmosphere for a Jupiter-mass exoplanet AI翻译
  作者：Fu, Guangwei; Welbanks, Luis; Deming, Drake; Inglis, Julie; Zhang, Michael; Lothringer, Joshua; Ih, Jegug; Moses, Julianne I.; Schlawin, Everett; Knutson, Heather A.; Henry, Gregory; Greene, Thomas; Sing, David K.; Savel, Arjun B.; Kempton, Eliza M. -R.; Louie, Dana R.; Line, Michael; Nixon, Matt
  作者单位：Johns Hopkins University; Arizona State University; Arizona State University-Tempe; University System of Maryland; University of Maryland College Park; California Institute of Technology; University of Chicago; Utah System of Higher Education; Utah Valley University; University of Arizona; Tennessee State University; National Aeronautics & Space Administration (NASA); NASA Ames Research Center; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center
  摘要：As the closest transiting hot Jupiter to Earth, HD 189733b has been the benchmark planet for atmospheric characterization(1-3). It has also been the anchor point for much of our theoretical understanding of exoplanet atmospheres from composition(4), chemistry(5,6), aerosols(7) to atmospheric dynamics(8), escape(9) and modelling techniques(10,11). Previous studies of HD 189733b have detected carbon and oxygen-bearing molecules H2O and CO (refs. 12,13) in the atmosphere. The presence of CO2 and ...
• Chiral kagome superconductivity modulations with residual Fermi arcs AI翻译
  作者：Deng, Hanbin; Qin, Hailang; Liu, Guowei; Yang, Tianyu; Fu, Ruiqing; Zhang, Zhongyi; Wu, Xianxin; Wang, Zhiwei; Shi, Youguo; Liu, Jinjin; Liu, Hongxiong; Yan, Xiao-Yu; Song, Wei; Xu, Xitong; Zhao, Yuanyuan; Yi, Mingsheng; Xu, Gang; Hohmann, Hendrik; Holbaek, Sofie Castro; Duerrnagel, Matteo; Zhou, Sen; Chang, Guoqing; Yao, Yugui; Wang, Qianghua; Guguchia, Zurab; Neupert, Titus; Thomale, Ronny; Fischer, Mark H.; Yin, Jia-Xin
  作者单位：Southern University of Science & Technology; Chinese Academy of Sciences; Institute of Theoretical Physics, CAS; Hong Kong University of Science & Technology; Beijing Institute of Technology; Beijing Institute of Technology; Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Physics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Songshan Lake Materials Laboratory; Chinese Academy of Sciences; Hefei Institutes of Physical Science, CAS; Huazhong University of Science & Technology; Huazhong University of Science & Technology; University of Wurzburg; University of Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; Nanyang Technological University; Nanjing University; Nanjing University; Swiss Federal Institutes of Technology Domain; Paul Scherrer Institute
  摘要：Superconductivity involving finite-momentum pairing(1) can lead to spatial-gap and pair-density modulations, as well as Bogoliubov Fermi states within the superconducting gap. However, the experimental realization of their intertwined relations has been challenging. Here we detect chiral kagome superconductivity modulations with residual Fermi arcs in KV3Sb5 and CsV3Sb5 using normal and Josephson scanning tunnelling microscopy down to 30 millikelvin with a resolved electronic energy difference...
• Author Correction: The enduring world forest carbon sink (vol 2, 2024, 17) AI翻译
  作者：Pan, Yude; Birdsey, Richard A.; Phillips, Oliver L.; Houghton, Richard A.; Fang, Jingyun; Kauppi, Pekka E.; Keith, Heather; Kurz, Werner A.; Ito, Akihiko; Lewis, Simon L.; Nabuurs, Gert-Jan; Shvidenko, Anatoly; Hashimoto, Shoji; Lerink, Bas; Schepaschenko, Dmitry; Castanho, Andrea; Murdiyarso, Daniel
  作者单位：United States Department of Agriculture (USDA); United States Forest Service; University of Leeds; Peking University; University of Helsinki; Swedish University of Agricultural Sciences; Griffith University; Griffith University - Gold Coast Campus; Natural Resources Canada; Canadian Forest Service; University of Tokyo; University of London; University College London; Wageningen University & Research; Wageningen University & Research; International Institute for Applied Systems Analysis (IIASA); Forestry & Forest Products Research Institute - Japan; Bogor Agricultural University