8039期

最新文章

• A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS AI翻译
  作者：Ocon, Borja; Xiang, Menglan; Bi, Yuhan; Tan, Serena; Brulois, Kevin; Ayesha, Aiman; Kunte, Manali; Zhou, Catherine; Lajevic, Melissa; Lazarus, Nicole; Mengoni, Francesca; Sharma, Tanya; Montgomery, Stephen; Hooper, Jody E.; Huang, Mian; Handel, Tracy; Dawson, John R. D.; Kufareva, Irina; Zabel, Brian A.; Pan, Junliang; Butcher, Eugene C.
  作者单位：Stanford University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Palo Alto Health Care System; University of Verona; University of Verona; University of California System; University of California San Diego
  摘要：Tissue-selective chemoattractants direct lymphocytes to epithelial surfaces to establish local immune environments, regulate immune responses to food antigens and commensal organisms, and protect from pathogens. Homeostatic chemoattractants for small intestines, colon and skin are known1,2, but chemotropic mechanisms selective for respiratory tract and other non-intestinal mucosal tissues remain poorly understood. Here we leveraged diverse omics datasets to identify GPR25 as a lymphocyte recep...
• Emissions from private jets are soaring AI翻译
  作者：Kudiabor, Helena
• Direct magnetic imaging of fractional Chern insulators in twisted MoTe2 AI翻译
  作者：Redekop, Evgeny; Zhang, Canxun; Park, Heonjoon; Cai, Jiaqi; Anderson, Eric; Sheekey, Owen; Arp, Trevor; Babikyan, Grigory; Salters, Samuel; Watanabe, Kenji; Taniguchi, Takashi; Huber, Martin E.; Xu, Xiaodong; Young, Andrea F.
  作者单位：University of California System; University of California Santa Barbara; University of Washington; University of Washington Seattle; National Institute for Materials Science; National Institute for Materials Science; University of Colorado System; University of Colorado Denver; University of Washington; University of Washington Seattle
  摘要：Orbital magnetization provides a sensitive probe of topology and interactions, with particularly rich phenomenology in Chern insulators in which the topological edge states carry large equilibrium currents. Here we use a nanoscale superconducting sensor1,2 to map the magnetic fringe fields in twisted bilayers of MoTe2, in which transport3,4 and optical sensing5,6 experiments have revealed the formation of fractional Chern insulator (FCI) states at zero magnetic field. We observe oscillations i...
• An integrated transcriptomic cell atlas of human neural organoids AI翻译
  作者：He, Zhisong; Dony, Leander; Fleck, Jonas Simon; Szalata, Artur; Li, Katelyn X.; Sliskovic, Irena; Lin, Hsiu-Chuan; Santel, Malgorzata; Atamian, Alexander; Quadrato, Giorgia; Sun, Jieran; Pasca, Sergiu P.; Camp, J. Gray; Theis, Fabian J.; Treutlein, Barbara
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; Max Planck Society; Technical University of Munich; Roche Holding; Technical University of Munich; University of Southern California; University of Southern California; Stanford University; University of Basel
  摘要：Human neural organoids, generated from pluripotent stem cells in vitro, are useful tools to study human brain development, evolution and disease. However, it is unclear which parts of the human brain are covered by existing protocols, and it has been difficult to quantitatively assess organoid variation and fidelity. Here we integrate 36 single-cell transcriptomic datasets spanning 26 protocols into one integrated human neural organoid cell atlas totalling more than 1.7 million cells1-26. Mapp...
• AI protein-prediction tool AlphaFold3 is now more open AI翻译
  作者：Callaway, Ewen
  摘要：The code underlying the Nobel-prize-winning tool for modelling protein structures can now be downloaded by academics.
• Health of people who are displaced in their own countries is a neglected global crisis AI翻译
  作者：Cantor, David; Roberts, Bayard; Swartz, Jina
  作者单位：University of London; University of London; London School of Hygiene & Tropical Medicine
  摘要：Compared with cross-border refugees, people who are internally displaced receive little attention - despite their dire health needs.
• Communicate the risk as well as the promise of weight-loss drugs AI翻译
  作者：Li, Bo; Li, Yu; Zhao, Zhihe; Li, Longjiang
  作者单位：Sichuan University
• Nobel research says don't dismantle DEI initiatives AI翻译
  作者：Shirani, Afsaneh
  作者单位：University of Nebraska System; University of Nebraska Medical Center
• Should Alzheimer's be diagnosed with a blood test? Proposal sparks controversy AI翻译
  作者：Kozlov, Max
  摘要：Proponents say that early diagnosis is beneficial. But opponents fear distress for people who might never develop symptoms.
• Global influence of soil texture on ecosystem water limitation AI翻译
  作者：Wankmuller, F. J. P.; Delval, L.; Lehmann, P.; Baur, M. J.; Cecere, A.; Wolf, S.; Or, D.; Javaux, M.; Carminati, A.
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Cambridge; University of Cambridge; Nevada System of Higher Education (NSHE); University of Nevada Reno; Helmholtz Association; Research Center Julich
  摘要：Low soil moisture and high vapour pressure deficit (VPD) cause plant water stress and lead to a variety of drought responses, including a reduction in transpiration and photosynthesis1,2. When soils dry below critical soil moisture thresholds, ecosystems transition from energy to water limitation as stomata close to alleviate water stress3,4. However, the mechanisms behind these thresholds remain poorly defined at the ecosystem scale. Here, by analysing observations of critical soil moisture t...