8039期

最新文章

• Is it really a sin if it's hardwired in? The neurological basis for 'bad' behaviour AI翻译
  作者：Peskin, Sara Manning
  作者单位：University of Pennsylvania
  摘要：A captivating examination of the biology that underlies behaviours often considered immoral raises questions about the existence of free will.
• A multi-omic atlas of human embryonic skeletal development AI翻译
  作者：To, Ken; Fei, Lijiang; Pett, J. Patrick; Roberts, Kenny; Blain, Raphael; Polanski, Krzysztof; Li, Tong; Yayon, Nadav; He, Peng; Xu, Chuan; Cranley, James; Moy, Madelyn; Li, Ruoyan; Kanemaru, Kazumasa; Huang, Ni; Megas, Stathis; Richardson, Laura; Kapuge, Rakesh; Perera, Shani L.; Tuck, Elizabeth; Wilbrey-Clark, Anna; Mulas, Ilaria; Memi, Fani; Cakir, Batuhan; Predeus, Alexander, V; Horsfall, David; Murray, Simon; Prete, Martin; Mazin, Pavel; He, Xiaoling; Meyer, Kerstin B.; Haniffe, Muzlifah; Barker, Roger A.; Bayraktar, Omer; Chedotal, Alain; Buckley, Christopher D.; Teichmanns, Sarah A.
  作者单位：Wellcome Trust Sanger Institute; University of Cambridge; Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; University of California System; University of California San Francisco; University of Cambridge; University of Cambridge; University of Cambridge; Newcastle University - UK; Newcastle Upon Tyne Hospitals NHS Foundation Trust; Newcastle University - UK; Newcastle University - UK; Newcastle Upon Tyne Hospitals NHS Foundation Trust; CHU Lyon; Universite Claude Bernard Lyon 1; Institut National de la Sante et de la Recherche Medicale (Inserm); University of Oxford; Kennedy Institute for Rheumatology; Canadian Institute for Advanced Research (CIFAR)
  摘要：Human embryonic bone and joint formation is determined by coordinated differentiation of progenitors in the nascent skeleton. The cell states, epigenetic processes and key regulatory factors that underlie lineage commitment of these cells remain elusive. Here we applied paired transcriptional and epigenetic profiling of approximately 336,000 nucleus droplets and spatial transcriptomics to establish a multi-omic atlas of human embryonic joint and cranium development between 5 and 11 weeks after...
• Perovskite/silicon tandem solar cells with bilayer interface passivation AI翻译
  作者：Liu, Jiang; He, Yongcai; Ding, Lei; Zhang, Hua; Li, Qiaoyan; Jia, Lingbo; Yu, Jia; Lau, Ting Wai; Li, Minghui; Qin, Yuan; Gu, Xiaobing; Zhang, Fu; Li, Qibo; Yang, Ying; Zhao, Shuangshuang; Wu, Xiaoyong; Liu, Jie; Liu, Tong; Gao, Yajun; Wang, Yonglei; Dong, Xin; Chen, Hao; Li, Ping; Zhou, Tianxiang; Yang, Miao; Ru, Xiaoning; Peng, Fuguo; Yin, Shi; Qu, Minghao; Zhao, Dongming; Zhao, Zhiguo; Li, Menglei; Guo, Penghui; Yan, Hui; Xiao, Chuanxiao; Xiao, Ping; Yin, Jun; Zhang, Xiaohong; Li, Zhenguo; He, Bo; Xu, Xixiang
  作者单位：Soochow University - China; Soochow University - China; Hong Kong Polytechnic University; Chinese Academy of Sciences; Ningbo Institute of Materials Technology & Engineering, CAS; Xi'an Jiaotong University; Beijing University of Technology
  摘要：Two-terminal monolithic perovskite/silicon tandem solar cells demonstrate huge advantages in power conversion efficiency compared with their respective single-junction counterparts1,2. However, suppressing interfacial recombination at the wide-bandgap perovskite/electron transport layer interface, without compromising its superior charge transport performance, remains a substantial challenge for perovskite/silicon tandem cells3,4. By exploiting the nanoscale discretely distributed lithium fluo...
• Google uses millions of phones to map Earth's ionosphere and improve GPS AI翻译
  作者：Gibney, Elizabeth
  摘要：Nanosecond-precision measurements from mobile devices could fill in gaps in satellite-navigation systems.
• A spatial human thymus cell atlas mapped to a continuous tissue axis AI翻译
  作者：Yayon, Nadav; Kedlian, Veronika R.; Boehme, Lena; Suo, Chenqu; Wachter, Brianna T.; Beuschel, Rebecca T.; Amsalem, Oren; Polanski, Krzysztof; Koplev, Simon; Tuck, Elizabeth; Dann, Emma; Van Hulle, Jolien; Perera, Shani; Putteman, Tom; Predeus, Alexander V.; Dabrowska, Monika; Richardson, Laura; Tudor, Catherine; Kreins, Alexandra Y.; Engelbert, Justin; Stephenson, Emily; Kleshchevnikov, Vitalii; De Rita, Fabrizio; Crossland, David; Bosticardo, Marita; Pala, Francesca; Prigmore, Elena; Chipampe, Nana-Jane; Prete, Martin; Fei, Lijiang; To, Ken; Barker, Roger A.; He, Xiaoling; Van Nieuwerburgh, Filip; Bayraktar, Omer Ali; Patel, Minal; Davies, E. Graham; Haniffa, Muzlifah A.; Uhlmann, Virginie; Notarangelo, Luigi D.; Germain, Ronald N.; Radtke, Andrea J.; Marioni, John C.; Taghon, Tom; Teichmann, Sarah A.
  作者单位：Wellcome Trust Sanger Institute; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; Ghent University; University of Cambridge; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Division of Intramural Research (DIR); National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Harvard University; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Harvard Medical School; University of London; University College London; Great Ormond Street Hospital for Children NHS Foundation Trust; University of London; University College London; Newcastle University - UK; Newcastle University - UK; Newcastle Freeman Hospital; University of Cambridge; University of Cambridge; Ghent University; Ghent University; Newcastle Upon Tyne Hospitals NHS Foundation Trust; Newcastle University - UK; Newcastle Upon Tyne Hospitals NHS Foundation Trust; Newcastle University - UK; CRUK Cambridge Institute; University of Cambridge; Cancer Research UK; University of Cambridge
  摘要：T cells develop from circulating precursor cells, which enter the thymus and migrate through specialized subcompartments that support their maturation and selection1. In humans, this process starts in early fetal development and is highly active until thymic involution in adolescence. To map the microanatomical underpinnings of this process in pre- and early postnatal stages, we established a quantitative morphological framework for the thymus-the Cortico-Medullary Axis-and used it to perform ...
• Words won't reduce the impact of conflict on nature - what's needed is action AI翻译
  作者：Dunn, Christopher P.; Mackey, Brendan; Gwiazdon, Kathryn
  作者单位：Cornell University; Griffith University; Griffith University - Gold Coast Campus; Northern Illinois University
• Huge carnivorous 'terror bird' rivalled the giant panda in size AI翻译
  作者：[Anonymous]
• Releasing a sugar brake generates sweeter tomato without yield penalty AI翻译
  作者：Zhang, Jinzhe; Lyu, Hongjun; Chen, Jie; Cao, Xue; Du, Ran; Ma, Liang; Wang, Nan; Zhu, Zhiguo; Rao, Jianglei; Wang, Jie; Zhong, Kui; Lyu, Yaqing; Wang, Yanling; Lin, Tao; Zhou, Yao; Zhou, Yongfeng; Zhu, Guangtao; Fei, Zhangjun; Klee, Harry; Huang, Sanwen
  作者单位：Chinese Academy of Agricultural Sciences; Institute of Vegetables & Flowers, CAAS; Chinese Academy of Agricultural Sciences; Agriculture Genomes Institute at Shenzhen, CAAS; China Academy of Chinese Medical Sciences; Institute of Chinese Materia Medica, CACMS; China Agricultural University; Yunnan Normal University; China National Institute of Standardization; China Agricultural University; Chinese Academy of Sciences; Institute of Botany, CAS; Cornell University; Boyce Thompson Institute for Plant Research; Chinese Academy of Tropical Agricultural Sciences
  摘要：In tomato, sugar content is highly correlated with consumer preferences, with most consumers preferring sweeter fruit1-4. However, the sugar content of commercial varieties is generally low, as it is inversely correlated with fruit size, and growers prioritize yield over flavour quality5-7. Here we identified two genes, tomato (Solanum lycopersicum) calcium-dependent protein kinase 27 (SlCDPK27; also known as SlCPK27) and its paralogue SlCDPK26, that control fruit sugar content. They act as su...
• Reply to: Concerns regarding proposed groundwater Earth system boundary AI翻译
  作者：Bunn, S. E.; Stewart-Koster, B.; Ndehedehe, C.; Gordon, C.; Rockstroem, J.; Gupta, J.; Qin, D.; Lade, S. J.
  作者单位：Griffith University; University of Ghana; Helmholtz Association; Helmholtz-Center Potsdam GFZ German Research Center for Geosciences; University of Potsdam; University of Amsterdam; IHE Delft Institute for Water Education; Chinese Academy of Sciences; China Meteorological Administration; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Stockholm University; Australian National University
• World-first stem-cell treatment restores vision in people AI翻译
  作者：Mallapaty, Smriti
  摘要：The treatment, given to four people with damaged corneas, seems safe but needs to be tested in larger trials.