8043期

最新文章

• A dormant overmassive black hole in the early Universe AI翻译
  作者：Juodzbalis, Ignas; Maiolino, Roberto; Baker, William M.; Tacchella, Sandro; Scholtz, Jan; D'Eugenio, Francesco; Witstok, Joris; Schneider, Raffaella; Trinca, Alessandro; Valiante, Rosa; Decoursey, Christa; Curti, Mirko; Carniani, Stefano; Chevallard, Jacopo; de Graaff, Anna; Arribas, Santiago; Bennett, Jake S.; Bourne, Martin A.; Bunker, Andrew J.; Charlot, Stephane; Jiang, Brian; Koudmani, Sophie; Perna, Michele; Robertson, Brant; Sijacki, Debora; Ubler, Hannah; Williams, Christina C.; Willott, Chris
  作者单位：University of Cambridge; University of Cambridge; Sapienza University Rome; Istituto Nazionale Astrofisica (INAF); Sapienza University Rome; University of Arizona; European Southern Observatory; Scuola Normale Superiore di Pisa; University of Oxford; Max Planck Society; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro de Astrobiologia (INTA); Harvard University; University of Cambridge; University of Hertfordshire; Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); University of Cambridge; Simons Foundation; Flatiron Institute; University of California System; University of California Santa Cruz; National Research Council Canada
  摘要：Recent observations have found a large number of supermassive black holes already in place in the first few hundred million years after the Big Bang, many of which seem to be overmassive relative to their host galaxy stellar mass when compared with local relation1, 2, 3, 4, 5, 6, 7, 8-9. Several different models have been proposed to explain these findings, ranging from heavy seeds to light seeds experiencing bursts of high accretion rate10, 11, 12, 13, 14, 15-16. Yet, current datasets are una...
• EXPRESS DELIVERY: ENGINEERED CELLS ZERO IN ON THE BRAIN AI翻译
  作者：[Anonymous]
• Genetic drivers and cellular selection of female mosaic X chromosome loss (vol 631, pg 134, 2024) AI翻译
  作者：Liu, Aoxing; Genovese, Giulio; Zhao, Yajie; Pirinen, Matti; Zekavat, Seyedeh M.; Kentistou, Katherine A.; Yang, Zhiyu; Yu, Kai; Vlasschaert, Caitlyn; Liu, Xiaoxi; Brown, Derek W.; Hudjashov, Georgi; Gorman, Bryan R.; Dennis, Joe; Zhou, Weiyin; Momozawa, Yukihide; Pyarajan, Saiju; Tuzov, Valdislav; Pajuste, Fanny-Dhelia; Aavikko, Mervi; Sipila, Timo P.; Ghazal, Awaisa; Huang, Wen-Yi; Freedman, Neal D.; Song, Lei; Gardner, Eugene J.; Sankaran, Vijay G.; Palotie, Aarno; Ollila, Hanna M.; Tukiainen, Taru; Chanock, Stephen J.; Magi, Reedik; Natarajan, Pradeep; Daly, Mark J.; Bick, Alexander; McCarroll, Steven A.; Terao, Chikashi; Loh, Po-Ru; Ganna, Andrea; Perry, John R. B.; Machiela, Mitchell J.
• Normal breast tissues harbour rare populations of aneuploid epithelial cells AI翻译
  作者：Lin, Yiyun; Wang, Junke; Wang, Kaile; Bai, Shanshan; Thennavan, Aatish; Wei, Runmin; Yan, Yun; Li, Jianzhuo; Elgamal, Heba; Sei, Emi; Casasent, Anna; Rao, Mitchell; Tang, Chenling; Multani, Asha S.; Ma, Jin; Montalvan, Jessica; Nagi, Chandandeep; Winocour, Sebastian; Lim, Bora; Thompson, Alastair; Navin, Nicholas
  作者单位：University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; Baylor College of Medicine; Baylor College of Medicine; University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center
  摘要：Aneuploid epithelial cells are common in breast cancer1,2; however, their presence in normal breast tissues is not well understood. To address this question, we applied single-cell DNA sequencing to profile copy number alterations in 83,206 epithelial cells from the breast tissues of 49 healthy women, and we applied single-cell DNA and assay for transposase-accessible chromatin sequencing co-assays to the samples of 19 women. Our data show that all women harboured rare aneuploid epithelial cel...
• Structural variation in the pangenome of wild and domesticated barley AI翻译
  作者：Jayakodi, Murukarthick; Lu, Qiongxian; Pidon, Helene; Rabanus-Wallace, M. Timothy; Bayer, Micha; Lux, Thomas; Guo, Yu; Jaegle, Benjamin; Badea, Ana; Bekele, Wubishet; Brar, Gurcharn S.; Braune, Katarzyna; Bunk, Boyke; Chalmers, Kenneth J.; Chapman, Brett; Jorgensen, Morten Egevang; Feng, Jia-Wu; Feser, Manuel; Fiebig, Anne; Gundlach, Heidrun; Guo, Wenbin; Haberer, Georg; Hansson, Mats; Himmelbach, Axel; Hoffie, Iris; Hoffie, Robert E.; Hu, Haifei; Isobe, Sachiko; Koenig, Patrick; Kale, Sandip M.; Kamal, Nadia; Keeble-Gagnere, Gabriel; Keller, Beat; Knauft, Manuela; Koppolu, Ravi; Krattinger, Simon G.; Kumlehn, Jochen; Langridge, Peter; Li, Chengdao; Marone, Marina P.; Maurer, Andreas; Mayer, Klaus F. X.; Melzer, Michael; Muehlbauer, Gary J.; Murozuka, Emiko; Padmarasu, Sudharsan; Perovic, Dragan; Pillen, Klaus; Pin, Pierre A.; Pozniak, Curtis J.; Ramsay, Luke; Pedas, Pai Rosager; Rutten, Twan; Sakuma, Shun; Sato, Kazuhiro; Schueler, Danuta; Schmutzer, Thomas; Scholz, Uwe; Schreiber, Miriam; Shirasawa, Kenta; Simpson, Craig; Skadhauge, Birgitte; Spannagl, Manuel; Steffenson, Brian J.; Thomsen, Hanne C.; Tibbits, Josquin F.; Nielsen, Martin Toft Simmelsgaard; Trautewig, Corinna; Vequaud, Dominique; Voss, Cynthia; Wang, Penghao; Waugh, Robbie; Westcott, Sharon; Rasmussen, Magnus Wohlfahrt; Zhang, Runxuan; Zhang, Xiao-Qi; Wicker, Thomas; Dockter, Christoph; Mascher, Martin; Stein, Nils
  作者单位：Leibniz Institut fur Pflanzengenetik und Kulturpflanzenforschung; Institut Agro; INRAE; Centre National de la Recherche Scientifique (CNRS); Universite de Montpellier; James Hutton Institute; Helmholtz Association; Helmholtz-Center Munich - German Research Center for Environmental Health; University of Zurich; Agriculture & Agri Food Canada; Agriculture & Agri Food Canada; University of British Columbia; Leibniz Association; Leibniz Institut fur Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); University of Adelaide; Murdoch University; Western Crop Genetics Alliance; Lund University; Guangdong Academy of Agricultural Sciences; Kazusa DNA Research Institute; La Trobe University; King Abdullah University of Science & Technology; Department of Primary Industries & Regional Development NSW; Yangtze University; Martin Luther University Halle Wittenberg; Technical University of Munich; University of Minnesota System; University of Minnesota Twin Cities; Julius Kuhn-Institut; University of Saskatchewan; University of Saskatchewan; Tottori University; Okayama University; University of Minnesota System; University of Minnesota Twin Cities; University of Dundee; German Research Foundation (DFG); German Centre for Integrative Biodiversity Research (iDiv); University of Alberta; Aarhus University
  摘要：Pangenomes are collections of annotated genome sequences of multiple individuals of a species1. The structural variants uncovered by these datasets are a major asset to genetic analysis in crop plants2. Here we report a pangenome of barley comprising long-read sequence assemblies of 76 wild and domesticated genomes and short-read sequence data of 1,315 genotypes. An expanded catalogue of sequence variation in the crop includes structurally complex loci that are rich in gene copy number variati...
• Andrew V. Schally obituary: Nobel prizewinner who transformed cancer therapies with research into brain hormones AI翻译
  作者：Cai, Renzi; Wangpaichitr, Medhi
  作者单位：Tulane University
• AI weatherman: the DeepMind researcher making faster, more accurate forecasts AI翻译
  作者：Castelvecchi, Davide
• Northern India and Pakistan are yet again engulfed in a haze of pollution - but a lasting solution is possible AI翻译
  作者：Guttikunda, Sarath K.
• Why probability probably doesn't exist (but it is useful to act like it does) AI翻译
  作者：Spiegelhalter, David
  作者单位：University of Cambridge
• Learning from others what cannot be learnt alone AI翻译
  作者：[Anonymous]