作者：Arseni, Diana; Nonaka, Takashi; Jacobsen, Max H.; Murzin, Alexey G.; Cracco, Laura; Peak-Chew, Sew Y.; Garringer, Holly J.; Kawakami, Ito; Suzuki, Hisaomi; Onaya, Misumoto; Saito, Yuko; Murayama, Shigeo; Geula, Changiz; Vidal, Ruben; Newell, Kathy L.; Mesulam, Marsel; Ghetti, Bernardino; Hasegawa, Masato; Ryskeldi-Falcon, Benjamin
作者单位：MRC Laboratory Molecular Biology; Tokyo Metropolitan Institute of Medical Science; Indiana University System; Indiana University Indianapolis; Northwestern University; Feinberg School of Medicine
摘要：Neurodegenerative diseases are characterized by the abnormal filamentous assembly of specific proteins in the central nervous system1. Human genetic studies have established a causal role for protein assembly in neurodegeneration2. However, the underlying molecular mechanisms remain largely unknown, which is limiting progress in developing clinical tools for these diseases. Recent advances in cryo-electron microscopy have enabled the structures of the protein filaments to be determined from th...
作者：Alfaro, R.; Alvarez, C.; Arteaga-Velazquez, J. C.; Rojas, D. Avila; Solares, H. A. Ayala; Babu, R.; Belmont-Moreno, E.; Caballero-Mora, K. S.; Capistran, T.; Carraminana, A.; Casanova, S.; Cotti, U.; Cotzomi, J.; de Leon, S. Coutino; De la Fuente, E.; Depaoli, D.; Di Lalla, N.; Diaz Hernandez, R.; Dingus, B. L.; DuVernois, M. A.; Durocher, M.; Diaz-Velez, J. C.; Engel, K.; Espinoza, C.; Fan, K. L.; Fang, K.; Fraija, N.; Fraija, S.; Garcia-Gonzalez, J. A.; Garcias, F.; Gonzalez Munoz, A.; Gonzalez, M. M.; Goodman, J. A.; Groetsch, S.; Harding, J. P.; Herzog, I; Hinton, J.; Huang, D.; Hueyotl-Zahuantitla, F.; Huntemeyer, P.; Iriarte, A.; Joshi, V; Kaufmann, S.; Kieda, D.; de Leon, C.; Lee, J.; Leon Vargas, H.; Linnemann, J. T.; Longinotti, A. L.; Luis-Raya, G.; Malone, K.; Martinez, O.; Martinez-Castro, J.; Matthews, J. A.; Miranda-Romagnoli, P.; Morales-Soto, J. A.; Moreno, E.; Mostafa, M.; Nayerhoda, A.; Nellen, L.; Newbold, M.; Nisa, M. U.; Noriega-Papaqui, R.; Olivera-Nieto, L.; Omodei, N.; Osorio, M.; Perez Araujo, Y.; Perez-Perez, E. G.; Rho, C. D.; Rosa-Gonzalez, D.; Ruiz-Velasco, E.; Salazar, H.; Salazar-Gallegos, D.; Sandoval, A.; Schneider, M.; Serna-Franco, J.; Smith, A. J.; Son, Y.; Springer, R. W.; Tibolla, O.; Tollefson, K.; Torres, I; Torres-Escobedo, R.; Turner, R.; Urena-Mena, F.; Varela, E.; Villasenor, L.; Wang, X.; Watson, I. J.; Willox, E.; Yun-Carcamo, S.; Zhou, H.
作者单位：Universidad Nacional Autonoma de Mexico; Universidad Autonoma de Chiapas; Universidad Michoacana de San Nicolas de Hidalgo; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Michigan Technological University; Universidad Nacional Autonoma de Mexico; Instituto Nacional de Astrofisica, Optica y Electronica; Polish Academy of Sciences; Institute of Nuclear Physics - Polish Academy of Sciences; Benemerita Universidad Autonoma de Puebla; University of Wisconsin System; University of Wisconsin Madison; Universidad de Guadalajara; Max Planck Society; Stanford University; United States Department of Energy (DOE); Los Alamos National Laboratory; University System of Maryland; University of Maryland College Park; Tecnologico de Monterrey; Michigan State University; University of Erlangen Nuremberg; Utah System of Higher Education; University of Utah; University of Seoul; United States Department of Energy (DOE); Los Alamos National Laboratory; Instituto Politecnico Nacional - Mexico; University of New Mexico; Universidad Autonoma del Estado de Hidalgo; Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University; Universidad Nacional Autonoma de Mexico; Sungkyunkwan University (SKKU); Shanghai Jiao Tong University
摘要：Microquasars are laboratories for the study of jets of relativistic particles produced by accretion onto a spinning black hole. Microquasars are near enough to allow detailed imaging of spatial features across the multiwavelength spectrum. The recent extension measurement of the spatial morphology of a microquasar, SS433, to TeV gamma rays(1) localizes the acceleration of electrons at shocks in the jet far from the black hole(2). V4641Sagittarii (V4641Sgr) is a similar binary system with a bla...
作者：Zhang, Feng; Zhang, Bo; Wang, Yuying; Jiang, Runmin; Liu, Jin; Wei, Yuexian; Gao, Xinyue; Zhu, Yichao; Wang, Xinli; Sun, Mao; Kang, Junjun; Liu, Yingying; You, Guoxing; Wei, Ding; Xin, Jiajia; Bao, Junxiang; Wang, Meiqing; Gu, Yu; Wang, Zhe; Ye, Jing; Guo, Shuangping; Huang, Hongyan; Sun, Qiang
作者单位：Air Force Medical University; Academy of Military Medical Sciences - China; Chinese Academy of Medical Sciences - Peking Union Medical College; Capital Medical University; Air Force Medical University; Air Force Medical University; Air Force Medical University; Air Force Medical University; Academy of Military Medical Sciences - China; Air Force Medical University; Air Force Medical University; Air Force Medical University; Air Force Medical University
