2024

最新文章

• Lethal Marburg virus is on the rise in Rwanda: why scientists are worried AI翻译
  作者：Sidik, Saima
  摘要：There is no proven vaccine or treatment for infections with the virus, which is closely related to Ebola virus and causes similar symptoms.
• Conservationists must address how war affects species and ecosystems AI翻译
  作者：Weir, Doug; Durant, Sarah M.; Schulte To Buehne, Henrike; Hoffmann, Michael; Petrovych, Olesya; Sua Carvajal, Beth; Fernandes Elizalde, Sara
  作者单位：University of London; King's College London; Zoological Society of London; Zoological Society of London
• Structure of a fully assembled γδ T cell antigen receptor AI翻译
  作者：Gully, Benjamin S.; Fernandes, Joao Ferreira; Gunasinghe, Sachith D.; Vuong, Mai T.; Lui, Yuan; Rice, Michael T.; Rashleigh, Liam; Lay, Chan-sien; Littler, Dene R.; Sharma, Sumana; Santos, Ana Mafalda; Venugopal, Hariprasad; Rossjohn, Jamie; Davis, Simon J.
  作者单位：Monash University; Monash University; University of Oxford; University of Oxford; Cardiff University
  摘要：T cells in jawed vertebrates comprise two lineages, alpha beta T cells and gamma delta T cells, defined by the antigen receptors they express-that is, alpha beta and gamma delta T cell receptors (TCRs), respectively. The two lineages have different immunological roles, requiring that gamma delta TCRs recognize more structurally diverse ligands1. Nevertheless, the receptors use shared CD3 subunits to initiate signalling. Whereas the structural organization of alpha beta TCRs is understood2,3, t...
• Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle AI翻译
  作者：Caserta, Leonardo C.; Frye, Elisha A.; Butt, Salman L.; Laverack, Melissa; Nooruzzaman, Mohammed; Covaleda, Lina M.; Thompson, Alexis C.; Koscielny, Melanie Prarat; Cronk, Brittany; Johnson, Ashley; Kleinhenz, Katie; Edwards, Erin E.; Gomez, Gabriel; Hitchener, Gavin; Martins, Mathias; Kapczynski, Darrell R.; Suarez, David L.; Morris, Ellen Ruth Alexander; Hensley, Terry; Beeby, John S.; Lejeune, Manigandan; Swinford, Amy K.; Elvinger, Francois; Dimitrov, Kiril M.; Diel, Diego G.
  作者单位：Cornell University; Texas A&M University System; Texas A&M University College Station; United States Department of Agriculture (USDA)
  摘要：The highly pathogenic avian influenza (HPAI) H5N1 virus clade 2.3.4.4b has caused the death of millions of domestic birds and thousands of wild birds in the USA since January 2022 (refs. 1-4). Throughout this outbreak, spillovers to mammals have been frequently documented5-12. Here we report spillover of the HPAI H5N1 virus to dairy cattle across several states in the USA. The affected cows displayed clinical signs encompassing decreased feed intake, altered faecal consistency, respiratory dis...
• Rwanda: seven swift steps for managing Marburg virus AI翻译
  作者：Rwagasore, Edson; Muvunyi, Claude Mambo; Butera, Yvan; Nsanzimana, Sabin; Condo, Jeanine
  作者单位：Rwanda Biomedical Center
• Molecular coupling goes from flat to 3D AI翻译
  作者：Sorbie, Jonathan A.; Diao, Tianning
  作者单位：New York University
• Olfactory neurons selectively respond to related visual and verbal cues AI翻译
  作者：Franks, Kevin M.; Schaefer, Andreas T.
  作者单位：Duke University; Francis Crick Institute
  摘要：What is the neural basis of our perceptual experience? Simultaneous recordings from many individual neurons in humans provide surprising insights into how odours are processed in different regions of the brain.
• Young asteroid families as the primary source of meteorites AI翻译
  作者：Broz, M.; Vernazza, P.; Marsset, M.; DeMeo, F. E.; Binzel, R. P.; Vokrouhlicky, D.; Nesvorny, D.
  作者单位：Charles University Prague; Aix-Marseille Universite; Centre National de la Recherche Scientifique (CNRS); Massachusetts Institute of Technology (MIT); Southwest Research Institute
  摘要：Understanding the origin of bright shooting stars and their meteorite samples is among the most ancient of astronomy-related questions, which at larger scales has human consequences(1-3). As of today, only approximately 6% of meteorite falls have been firmly linked to their sources (Moon, Mars or asteroid (4) Vesta(4-6)). Here we show that approximately 70% of meteorites originate from three recent break-ups of D > 30 km asteroids that occurred 5.8, 7.6 and less than about 40 Myr ago. These br...
• Most of Earth's meteorites come from three young asteroid families AI翻译
  作者：Granvik, Mikael
  作者单位：University of Helsinki; Lulea University of Technology
  摘要：Researchers have narrowed down the sources of the most common types of meteorite to a few collisional events that happened much more recently than was previously thought.
• Electrocatalytic reductive deuteration of arenes and heteroarenes AI翻译
  作者：Bu, Faxiang; Deng, Yuqi; Xu, Jie; Yang, Dali; Li, Yan; Li, Wu; Lei, Aiwen
  作者单位：Wuhan University
  摘要：The incorporation of deuterium in organic molecules has widespread applications in medicinal chemistry and materials science1,2. For example, the deuterated drugs austedo3, donafenib4 and sotyktu5 have been recently approved. There are various methods for the synthesis of deuterated compounds with high deuterium incorporation6. However, the reductive deuteration of aromatic hydrocarbons-ubiquitous chemical feedstocks-to saturated cyclic compounds has rarely been achieved. Here we describe a sc...