2024

最新文章

• THE TRY-IT-ALL APPROACH TO PRECISION MEDICINE AI翻译
  作者：Dolgin, Elie
• Critical transitions in the Amazon forest system AI翻译
  作者：Flores, Bernardo M.; Montoya, Encarni; Sakschewski, Boris; Nascimento, Nathalia; Staal, Arie; Betts, Richard A.; Levis, Carolina; Lapola, David M.; Esquivel-Muelbert, Adriane; Jakovac, Catarina; Nobre, Carlos A.; Oliveira, Rafael S.; Borma, Laura S.; Nian, Da; Boers, Niklas; Hecht, Susanna B.; ter Steege, Hans; Arieira, Julia; Lucas, Isabella L.; Berenguer, Erika; Marengo, Jose A.; Gatti, Luciana V.; Mattos, Caio R. C.; Hirota, Marina
  作者单位：Universidade Federal de Santa Catarina (UFSC); Consejo Superior de Investigaciones Cientificas (CSIC); Potsdam Institut fur Klimafolgenforschung; Universidade de Sao Paulo; Utrecht University; Met Office - UK; Hadley Centre; University of Exeter; Universidade Estadual de Campinas; University of Birmingham; University of Birmingham; Universidade Federal de Santa Catarina (UFSC); Universidade Estadual de Campinas; Instituto Nacional de Pesquisas Espaciais (INPE); Technical University of Munich; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Naturalis Biodiversity Center; Utrecht University; University of Oxford; Universidade Estadual Paulista; Korea University; National Oceanic Atmospheric Admin (NOAA) - USA; Princeton University; Universidade Federal de Santa Catarina (UFSC)
  摘要：The possibility that the Amazon forest system could soon reach a tipping point, inducing large-scale collapse, has raised global concern1-3. For 65 million years, Amazonian forests remained relatively resilient to climatic variability. Now, the region is increasingly exposed to unprecedented stress from warming temperatures, extreme droughts, deforestation and fires, even in central and remote parts of the system1. Long existing feedbacks between the forest and environmental conditions are bei...
• JWST is most in-demand telescope ever - leaving many astronomers in the cold AI翻译
  作者：Rao, Rahul
• Non-Abelian topological order and anyons on a trapped-ion processor AI翻译
  作者：Iqbal, Mohsin; Tantivasadakarn, Nathanan; Verresen, Ruben; Campbell, Sara L.; Dreiling, Joan M.; Figgatt, Caroline; Gaebler, John P.; Johansen, Jacob; Mills, Michael; Moses, Steven A.; Pino, Juan M.; Ransford, Anthony; Rowe, Mary; Siegfried, Peter; Stutz, Russell P.; Foss-Feig, Michael; Vishwanath, Ashvin; Dreyer, Henrik
  作者单位：California Institute of Technology; California Institute of Technology; Harvard University
  摘要：Non-Abelian topological order is a coveted state of matter with remarkable properties, including quasiparticles that can remember the sequence in which they are exchanged1-4. These anyonic excitations are promising building blocks of fault-tolerant quantum computers5,6. However, despite extensive efforts, non-Abelian topological order and its excitations have remained elusive, unlike the simpler quasiparticles or defects in Abelian topological order. Here we present the realization of non-Abel...
• Single-neuronal elements of speech production in humans AI翻译
  作者：Khanna, Arjun R.; Munoz, William; Kim, Young Joon; Kfir, Yoav; Paulk, Angelique C.; Jamali, Mohsen; Cai, Jing; Mustroph, Martina L.; Caprara, Irene; Hardstone, Richard; Mejdell, Mackenna; Meszena, Domokos; Zuckerman, Abigail; Schweitzer, Jeffrey; Cash, Sydney; Williams, Ziv M.
  作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard Medical School; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard Medical School; Harvard University; Harvard University; Harvard Medical School
  摘要：Humans are capable of generating extraordinarily diverse articulatory movement combinations to produce meaningful speech. This ability to orchestrate specific phonetic sequences, and their syllabification and inflection over subsecond timescales allows us to produce thousands of word sounds and is a core component of language(1,2). The fundamental cellular units and constructs by which we plan and produce words during speech, however, remain largely unknown. Here, using acute ultrahigh-density...
• The Bill Gates Problem: Reckoning with the Myth of the Good Billionaire AI翻译
  作者：Stirling, Andy
  作者单位：University of Sussex
  摘要：Personal priorities are often trumping real needs and skewing where charitable funding goes.
• Coordination of cohesin and DNA replication observed with purified proteins AI翻译
  作者：Murayama, Yasuto; Endo, Shizuko; Kurokawa, Yumiko; Kurita, Ayako; Iwasaki, Sanae; Araki, Hiroyuki
  作者单位：Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan; Japan Science & Technology Agency (JST); Research Organization of Information & Systems (ROIS)
  摘要：Two newly duplicated copies of genomic DNA are held together by the ring-shaped cohesin complex to ensure faithful inheritance of the genome during cell division(1-3). Cohesin mediates sister chromatid cohesion by topologically entrapping two sister DNAs during DNA replication(4,5), but how cohesion is established at the replication fork is poorly understood. Here, we studied the interplay between cohesin and replication by reconstituting a functional replisome using purified proteins. Once DN...
• Best practice for LGBTQ plus data collection by STEM organizations AI翻译
  作者：Bond, Alexander L.; Kelly, Tyler L.
  作者单位：Natural History Museum London; University of Birmingham
  摘要：Letter to the Editor
• Ultracold field-linked tetratomic molecules AI翻译
  作者：Chen, Xing-Yan; Biswas, Shrestha; Eppelt, Sebastian; Schindewolf, Andreas; Deng, Fulin; Shi, Tao; Yi, Su; Hilker, Timon A.; Bloch, Immanuel; Luo, Xin-Yu
  作者单位：Max Planck Society; Wuhan University; Chinese Academy of Sciences; Institute of Theoretical Physics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Beihang University; University of Munich
  摘要：Ultracold polyatomic molecules offer opportunities1 in cold chemistry2,3, precision measurements4 and quantum information processing5,6, because of their rich internal structure. However, their increased complexity compared with diatomic molecules presents a challenge in using conventional cooling techniques. Here we demonstrate an approach to create weakly bound ultracold polyatomic molecules by electroassociation7 (F.D. et al., manuscript in preparation) in a degenerate Fermi gas of microwav...
• A break in mitochondrial endosymbiosis as a basis for inflammatory diseases AI翻译
  作者：Murphy, Michael P.; O'Neill, Luke A. J.
  作者单位：University of Cambridge; University of Cambridge; Trinity College Dublin
  摘要：Mitochondria retain bacterial traits due to their endosymbiotic origin, but host cells do not recognize them as foreign because the organelles are sequestered. However, the regulated release of mitochondrial factors into the cytosol can trigger cell death, innate immunity and inflammation. This selective breakdown in the 2-billion-year-old endosymbiotic relationship enables mitochondria to act as intracellular signalling hubs. Mitochondrial signals include proteins, nucleic acids, phospholipid...