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作者：Lin, Ruei-Zeng; Im, Gwang-Bum; Luo, Allen Chilun; Zhu, Yonglin; Hong, Xuechong; Neumeyer, Joseph; Tang, Hong-Wen; Perrimon, Norbert; Melero-Martin, Juan M.
作者单位：Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; Howard Hughes Medical Institute; Harvard University; Harvard Medical School; Harvard University
摘要：Ischaemic diseases such as critical limb ischaemia and myocardial infarction affect millions of people worldwide1. Transplanting endothelial cells (ECs) is a promising therapy in vascular medicine, but engrafting ECs typically necessitates co-transplanting perivascular supporting cells such as mesenchymal stromal cells (MSCs), which makes clinical implementation complicated2,3. The mechanisms that enable MSCs to facilitate EC engraftment remain elusive. Here we show that, under cellular stress...
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作者：Ghosh, Pratyush; Alvertis, Antonios M.; Chowdhury, Rituparno; Murto, Petri; Gillett, Alexander J.; Dong, Shengzhi; Sneyd, Alexander J.; Cho, Hwan-Hee; Evans, Emrys W.; Monserrat, Bartomeu; Li, Feng; Schnedermann, Christoph; Bronstein, Hugo; Friend, Richard H.; Rao, Akshay
作者单位：University of Cambridge; National Aeronautics & Space Administration (NASA); NASA Ames Research Center; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of Cambridge; Jilin University; Swansea University; University of Cambridge
摘要：The coupling of excitons in pi-conjugated molecules to high-frequency vibrational modes, particularly carbon-carbon stretch modes (1,000-1,600 cm-1) has been thought to be unavoidable 1,2 . These high-frequency modes accelerate non-radiative losses and limit the performance of light-emitting diodes, fluorescent biomarkers and photovoltaic devices. Here, by combining broadband impulsive vibrational spectroscopy, first-principles modelling and synthetic chemistry, we explore exciton-vibration co...
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作者：Tollefson, Jeff
摘要：Some scientists argue that it's time to rethink the blanket policy of letting blazes burn themselves out in northern wildernesses.
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作者：Doan, Alexander E.; Mueller, Katherine P.; Chen, Andy Y.; Rouin, Geoffrey T.; Chen, Yingshi; Daniel, Bence; Lattin, John; Markovska, Martina; Mozarsky, Brett; Arias-Umana, Jose; Hapke, Robert; Jung, In-Young; Wang, Alice; Xu, Peng; Klysz, Dorota; Zuern, Gabrielle; Bashti, Malek; Quinn, Patrick J.; Miao, Zhuang; Sandor, Katalin; Zhang, Wenxi; Chen, Gregory M.; Ryu, Faith; Logun, Meghan; Hall, Junior; Tan, Kai; Grupp, Stephan A.; Mcclory, Susan E.; Lareau, Caleb A.; Fraietta, Joseph A.; Sotillo, Elena; Satpathy, Ansuman T.; Mackall, Crystal L.; Weber, Evan W.
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作者：Chung, Changuk; Yang, Xiaoxu; Hevner, Robert F.; Kennedy, Katie; Vong, Keng Ioi; Liu, Yang; Patel, Arzoo; Nedunuri, Rahul; Barton, Scott T.; Noel, Geoffroy; Barrows, Chelsea; Stanley, Valentina; Mittal, Swapnil; Breuss, Martin W.; Schlachetzki, Johannes C. M.; Kingsmore, Stephen F.; Gleeson, Joseph G.
作者单位：University of California System; University of California San Diego; Utah System of Higher Education; University of Utah; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of Colorado System; University of Colorado Anschutz Medical Campus; University of California System; University of California San Diego
摘要：Debate remains around the anatomical origins of specific brain cell subtypes and lineage relationships within the human forebrain1-7. Thus, direct observation in the mature human brain is critical for a complete understanding of its structural organization and cellular origins. Here we utilize brain mosaic variation within specific cell types as distinct indicators for clonal dynamics, denoted as cell-type-specific mosaic variant barcode analysis. From four hemispheres and two different human ...
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作者：Chawla, Dalmeet Singh
摘要：Browser plug-in alerts users when studies - or their references - have been posted on a site known for raising integrity concerns. Browser plug-in alerts users when studies - or their references - have been posted on a site known for raising integrity concerns. A magnifying glass illuminated by the screen of a partial open laptop in the dark.
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作者：Montano, Simone; Siena, Federica; Strona, Giovanni
作者单位：University of Milano-Bicocca; European Commission Joint Research Centre; EC JRC ISPRA Site
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作者：Williams, Ziv
作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard Medical School
摘要：How does the human brain temporarily store information without losing track of it? Neuroscientists have discovered that neurons in the frontal and temporal lobes work together to hold information in working memory.
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作者：[Anonymous]
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作者：Ding, S.; Garofalo, A. M.; Wang, H. Q.; Weisberg, D. B.; Li, Z. Y.; Jian, X.; Eldon, D.; Victor, B. S.; Marinoni, A.; Hu, Q. M.; Carvalho, I. S.; Odstrcil, T.; Wang, L.; Hyatt, A. W.; Osborne, T. H.; Gong, X. Z.; Qian, J. P.; Huang, J.; McClenaghan, J.; Holcomb, C. T.; Hanson, J. M.
作者单位：General Atomics & Affiliated Companies; United States Department of Energy (DOE); Lawrence Livermore National Laboratory; Massachusetts Institute of Technology (MIT); Princeton University; United States Department of Energy (DOE); Princeton Plasma Physics Laboratory; Chinese Academy of Sciences; Hefei Institutes of Physical Science, CAS; Columbia University
摘要：The tokamak approach, utilizing a toroidal magnetic field configuration to confine a hot plasma, is one of the most promising designs for developing reactors that can exploit nuclear fusion to generate electrical energy(1,2). To reach the goal of an economical reactor, most tokamak reactor designs(3-10) simultaneously require reaching a plasma line-averaged density above an empirical limit-the so-called Greenwald density(11)-and attaining an energy confinement quality better than the standard ...
