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作者：[Anonymous]
摘要：From petrol to plastics, oil-derived products define modern life. A bold plan to change that comes with huge costs - but researchers and policymakers should take it seriously.
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作者：Li, Jing; Cheng, Rui; Wang, Zhiming; Yuan, Wuliu; Xiao, Jun; Zhao, Xinyuan; Du, Xinran; Xia, Shiyu; Wang, Lianrong; Zhu, Bin; Wang, Longfei
作者单位：Wuhan University; Wuhan University; Wuhan University; Wuhan University; Wuhan University; Huazhong University of Science & Technology; Wuhan University; California Institute of Technology; Wuhan University
摘要：Prokaryotes have evolved intricate innate immune systems against phage infection1-7. Gabija is a highly widespread prokaryotic defence system that consists of two components, GajA and GajB8. GajA functions as a DNA endonuclease that is inactive in the presence of ATP9. Here, to explore how the Gabija system is activated for anti-phage defence, we report its cryo-electron microscopy structures in five states, including apo GajA, GajA in complex with DNA, GajA bound by ATP, apo GajA-GajB, and Ga...
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作者：Callaway, Ewen
摘要：Some of the AI-designed gene editors could be more versatile than those found in nature.
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作者：Castelvecchi, Davide
摘要：The first set of results from a pioneering cosmic-mapping project hints that the repulsive force known as dark energy has changed over 11 billion years, which would alter ideas about how the Universe has evolved and what its future will be.
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作者：Montano, Simone; Siena, Federica; Strona, Giovanni
作者单位：University of Milano-Bicocca; European Commission Joint Research Centre; EC JRC ISPRA Site
摘要：Letter to the Editor
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作者：Prichard, Max L.; Spar, Benjamin M.; Morera, Ivan; Demler, Eugene; Yan, Zoe Z.; Bakr, Waseem S.
作者单位：Princeton University; University of Barcelona; University of Barcelona; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Chicago; University of Chicago
摘要：The emergence of quasiparticles in quantum many-body systems underlies the rich phenomenology in many strongly interacting materials. In the context of doped Mott insulators, magnetic polarons are quasiparticles that usually arise from an interplay between the kinetic energy of doped charge carriers and superexchange spin interactions1-8. However, in kinetically frustrated lattices, itinerant spin polarons-bound states of a dopant and a spin flip-have been theoretically predicted even in the a...
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作者：Abbott, Alison
摘要：Our immune system falters over time, which could explain the negative effects of ageing.
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作者：Lorenzo-Martin, L. Francisco; Huebscher, Tania; Bowler, Amber D.; Broguiere, Nicolas; Langer, Jakob; Tillard, Lucie; Nikolaev, Mikhail; Radtke, Freddy; Lutolf, Matthias P.
作者单位：Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Institute Experimental Cancer Research; Swiss School of Public Health (SSPH+); Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要：Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of both tumour and microenvironmental structures(1-3). This has enabled better modelling of low-complexity cancer cell behaviours that occur over relatively short periods of time(4). However, available organoid systems do not capture the intricate evolutionary process of cancer development in terms of tissue architecture, cell diversity, homeostasis and ...
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作者：Lindenmayer, David; Zylstra, Philip
作者单位：Australian National University
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作者：Maiuri, Margherita
作者单位：Polytechnic University of Milan
摘要：The development of high-performance organic LEDs and other devices that emit near-infrared light has been hindered by seemingly fundamental features of the light-emitting molecules. A potential solution has been identified.
