作者：Laepple, T.; Muench, T.; Hirsch, N.; Shaw, F.; Hoerhold, M.
作者单位：Helmholtz Association; Alfred Wegener Institute, Helmholtz Centre for Polar & Marine Research; University of Bremen; Helmholtz Association; Alfred Wegener Institute, Helmholtz Centre for Polar & Marine Research
作者：Collingham, Lizzie
作者单位：University of Cambridge
摘要：For centuries we've linked what we consume to how we feel about ourselves. . By Lizzie Collingham
作者：Chun, Hyeon Young; Park, Tae Jung
作者单位：Korea Advanced Institute of Science & Technology (KAIST)
作者：Fardian-Melamed, Natalie; Skripka, Artiom; Ursprung, Benedikt; Lee, Changhwan; Darlington, Thomas P.; Teitelboim, Ayelet; Qi, Xiao; Wang, Maoji; Gerton, Jordan M.; Cohen, Bruce E.; Chan, Emory M.; Schuck, P. James
作者单位：Columbia University; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Autonomous University of Madrid; Utah System of Higher Education; University of Utah; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Oregon State University
摘要：Mechanical force is an essential feature for many physical and biological processes1, 2, 3, 4, 5, 6-7, and remote measurement of mechanical signals with high sensitivity and spatial resolution is needed for diverse applications, including robotics8, biophysics9,10, energy storage11 and medicine12,13. Nanoscale luminescent force sensors excel at measuring piconewton forces, whereas larger sensors have proven powerful in probing micronewton forces14, 15-16. However, large gaps remain in the forc...
作者：Casar, Jason R.; Mclellan, Claire A.; Shi, Cindy; Stiber, Ariel; Lay, Alice; Siefe, Chris; Parakh, Abhinav; Gaerlan, Malaya; Gu, X. Wendy; Goodman, Miriam B.; Dionne, Jennifer A.
作者单位：Stanford University; Stanford University; United States Department of Energy (DOE); Lawrence Livermore National Laboratory; Stanford University; Stanford University; Stanford University; Stanford Medicine; Stanford Medicine; Stanford University; Chan Zuckerberg Initiative (CZI)
摘要：The forces generated by action potentials in muscle cells shuttle blood, food and waste products throughout the luminal structures of the body. Although non-invasive electrophysiological techniques exist1, 2-3, most mechanosensors cannot access luminal structures non-invasively4, 5-6. Here we introduce non-toxic ingestible mechanosensors to enable the quantitative study of luminal forces and apply them to study feeding in living Caenorhabditis elegans roundworms. These optical 'microgauges' co...
