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作者:Jones, Tyler R.; Cuffey, Kurt M.; Steig, Eric J.; Markle, Bradley R.
作者单位:University of Colorado System; University of Colorado Boulder; University of California System; University of California Berkeley; University of Washington; University of Washington Seattle; University of Colorado System; University of Colorado Boulder
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作者:Ghosh, Madhurima; Chatterji, Biswa Prasun
作者单位:Assam Down Town University
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作者:Stoof, Cathelijne; Ribau, Marc Castellnou; Moore, Peter F.; Boustras, Georgios
作者单位:Wageningen University & Research; European University Cyprus
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作者:Speidel, Leo; Silva, Marina; Booth, Thomas; Raffield, Ben; Anastasiadou, Kyriaki; Barrington, Christopher; Gotherstroem, Anders; Heather, Peter; Skoglund, Pontus
作者单位:Francis Crick Institute; University of London; University College London; RIKEN; Uppsala University; Francis Crick Institute; Stockholm University; Swedish Museum of Natural History; Stockholm University; University of London; King's College London
摘要:Many known and unknown historical events have remained below detection thresholds of genetic studies because subtle ancestry changes are challenging to reconstruct. Methods based on shared haplotypes1,2 and rare variants3,4 improve power but are not explicitly temporal and have not been possible to adopt in unbiased ancestry models. Here we develop Twigstats, an approach of time-stratified ancestry analysis that can improve statistical power by an order of magnitude by focusing on coalescences...
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作者:Busch, Wolfgang
作者单位:Salk Institute
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作者:Cheng, Dali; Wang, Kai; Roques-Carmes, Charles; Lustig, Eran; Long, Olivia Y.; Wang, Heming; Fan, Shanhui
作者单位:Stanford University; Stanford University; McGill University; Stanford University
摘要:Non-Abelian gauge fields1 provide a conceptual framework to describe particles having spins, underlying many phenomena in electrodynamics, condensed-matter physics2,3 and particle physics4,5. Lattice models6 of non-Abelian gauge fields allow us to understand their physical implications in extended systems. The theoretical importance of non-Abelian lattice gauge fields motivates their experimental synthesis and explorations7, 8-9. Photons are fundamental particles for which artificial gauge fie...
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作者:Lam, Norman H.; Mukherjee, Arghya; Wimmer, Ralf D.; Nassar, Matthew R.; Chen, Zhe Sage; Halassa, Michael M.
作者单位:Tufts University; Brown University; New York University; New York University; Tufts University
摘要:Making adaptive decisions in complex environments requires appropriately identifying sources of error1,2. The frontal cortex is critical for adaptive decisions, but its neurons show mixed selectivity to task features3 and their uncertainty estimates4, raising the question of how errors are attributed to their most likely causes. Here, by recording neural responses from tree shrews (Tupaia belangeri) performing a hierarchical decision task with rule reversals, we find that the mediodorsal thala...
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作者:Meijerink, Andries
作者单位:Utrecht University
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作者:Woolston, Chris
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作者:Beghini, Francesco; Pullman, Jackson; Alexander, Marcus; Shridhar, Shivkumar Vishnempet; Prinster, Drew; Singh, Adarsh; Juarez, Rigoberto Matute; Airoldi, Edoardo M.; Brito, Ilana L.; Christakis, Nicholas A.
作者单位:Yale University; Yale University; Yale University; Johns Hopkins University; Cornell University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University; Yale University
摘要:When humans assemble into face-to-face social networks, they create an extended social environment that permits exposure to the microbiome of others, thereby shaping the composition and diversity of the microbiome at individual and population levels1-6. Here we use comprehensive social network mapping and detailed microbiome sequencing data in 1,787 adults within 18 isolated villages in Honduras7 to investigate the relationship between network structure and gut microbiome composition. Using bo...