8045期

最新文章

• This digital-memory device keeps its cool even at 600 °C AI翻译
  作者：[Anonymous]
• Fetal hepatocytes protect the HSPC genome via fetuin-A AI翻译
  作者：Guo, Xiao-Lin; Wang, Yi-Ding; Liu, Yan-Jun; Chu, Lei; Zhu, Hua; Hu, Ye; Wu, Ren-Yan; Xie, Hong-Yu; Yu, Juan; Li, Shui-Ping; Xiong, Zhao-Yang; Li, Ruo-Yan; Ke, Fang; Chen, Lei; Chen, Guo-Qiang; Chen, Liang; Bai, Fan; Enver, Tariq; Li, Guo-Hong; Li, Huai-Fang; Hong, Deng-Li
  作者单位：Shanghai Jiao Tong University; Tongji University; Shanghai Jiao Tong University; Chinese Academy of Sciences; Institute of Biophysics, CAS; Peking University; Peking University; Chinese Academy of Sciences; Shanghai Jiao Tong University; Shanghai Jiao Tong University; Chinese Academy of Medical Sciences - Peking Union Medical College; Shanghai Jiao Tong University; Chinese Academy of Medical Sciences - Peking Union Medical College; Hainan Medical University; Wuhan University; University of London; University College London; Shanghai Jiao Tong University
  摘要：The maintenance of genomic integrity in rapidly proliferating cells is a substantial challenge during embryonic development(1-3). Although numerous cell-intrinsic mechanisms have been revealed(4-7), little is known about genome-protective effects and influences of developmental tissue microenvironments on tissue-forming cells. Here we show that fetal liver hepatocytes provide protection to haematopoietic stem and progenitor cell (HSPC) genomes. Lineage tracing and depletion in mice demonstrate...
• Pan-genome bridges wheat structural variations with habitat and breeding AI翻译
  作者：Jiao, Chengzhi; Xie, Xiaoming; Hao, Chenyang; Chen, Liyang; Xie, Yuxin; Garg, Vanika; Zhao, Li; Wang, Zihao; Zhang, Yuqi; Li, Tian; Fu, Junjie; Chitikineni, Annapurna; Hou, Jian; Liu, Hongxia; Dwivedi, Girish; Liu, Xu; Jia, Jizeng; Mao, Long; Wang, Xiue; Appels, Rudi; Varshney, Rajeev K.; Guo, Weilong; Zhang, Xueyong
  作者单位：Chinese Academy of Agricultural Sciences; Institute of Crop Sciences, CAAS; Nanjing Agricultural University; China Agricultural University; Murdoch University; Harry Perkins Institute of Medical Research; University of Western Australia; South Metropolitan Health Service; Fiona Stanley Fremantle Hospitals Group; Fiona Stanley Hospital; La Trobe University; Department of Economic Development, Jobs, Transport & Resources
  摘要：Wheat is the second largest food crop with a very good breeding system and pedigree record in China. Investigating the genomic footprints of wheat cultivars will unveil potential avenues for future breeding efforts(1,2). Here we report chromosome-level genome assemblies of 17 wheat cultivars that chronicle the breeding history of China. Comparative genomic analysis uncovered a wealth of structural rearrangements, identifying 249,976 structural variations with 49.03% (122,567) longer than 5 kb....
• Light-harvesting microelectronic devices for wireless electrosynthesis AI翻译
  作者：Gorski, Bartosz; Rein, Jonas; Norris, Samantha; Ji, Yanxin; McEuen, Paul L.; Lin, Song
  作者单位：Cornell University; Cornell University; Cornell University
  摘要：High-throughput experimentation (HTE) has accelerated academic and industrial chemical research in reaction development and drug discovery and has been broadly applied in many domains of organic chemistry(1,2). However, application of HTE in electrosynthesis-an enabling tool for chemical synthesis-has been limited by a dearth of suitable standardized reactors(3-7). Here we report the development of microelectronic devices, which are produced using standard nanofabrication techniques, to enable...
• Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation AI翻译
  作者：Valenstein, Max L.; Lalgudi, Pranav V.; Kedir, Jibril F.; Condon, Kendall J.; Platzek, Anna; Freund, Daniel G.; Taylor, Martin S.; Xu, Yunhan; Chivukula, Raghu R.; Sabatini, David M.
  作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Massachusetts Institute of Technology (MIT); Whitehead Institute; Massachusetts Institute of Technology (MIT); Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Czech Academy of Sciences; Institute of Organic Chemistry & Biochemistry of the Czech Academy of Sciences
• The revolutionary dawn of quantum mechanics AI翻译
  作者：Camilleri, Kristian
  作者单位：University of Melbourne
• Biodiversity credits are more problematic than carbon credits AI翻译
  作者：Law, Kelvin
  作者单位：Nanyang Technological University
• The AI tool that can interpret any spreadsheet instantly AI翻译
  作者：McElfresh, Duncan C.
  作者单位：Stanford University; Stanford Medicine
  摘要：Artificial intelligence is already used extensively to infer outcomes from tables of data, but this typically involves creating a model for each task. A one-size-fits-all model just made the process substantially easier. A generalized model for tabular machine learning.
• Particle exchange statistics beyond fermions and bosons AI翻译
  作者：Wang, Zhiyuan; Hazzard, Kaden R. A.
  作者单位：Rice University; Rice University; Max Planck Society
  摘要：It is commonly believed that there are only two types of particle exchange statistics in quantum mechanics, fermions and bosons, with the exception of anyons in two dimensions(1-5). In principle, a second exception known as parastatistics, which extends outside two dimensions, has been considered(6) but was believed to be physically equivalent to fermions and bosons(7-9). Here we show that non-trivial parastatistics inequivalent to either fermions or bosons can exist in physical systems. These...
• Dread and determination: how climate scientists are preparing for Trump 2.0 AI翻译
  作者：Witze, Alexandra